Patents by Inventor Eric Miska

Eric Miska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of miRNA Activity
    Publication number: 20120184457
    Abstract: Provided is a method of identifying a compound which modulates miRNA activity comprising (i) determining the ability of a test compound to alter the polyuridylation activity of a ZCCHC polypeptide wherein a test compound which alters the polyuridylation activity is useful in modulating miRNA activity; or (ii) determining the ability of a test compound to alter the binding of a ZCCHC polypeptide to a LIN28 polypeptide, wherein a test compound which alters said binding may be useful in modulating miRNA activity; or (iii) determining the ability of a test compound to bind to a ZCCHC polypeptide, wherein a test compound which binds to the ZCCHC polypeptide may be useful in modulating miRNA activity.
    Type: Application
    Filed: August 6, 2010
    Publication date: July 19, 2012
    Applicant: Cambridge Enterprise Limited
    Inventors: Eric Miska, Nicolas Lehrbach, Javier Armisen-Garrido, Shankar Balasubramanian
  • High throughput methods relating to microRNA expression analysis
    Patent number: 7635563
    Abstract: The invention relates to methods and compositions for microRNA expression analysis using microarrays.
    Type: Grant
    Filed: June 30, 2005
    Date of Patent: December 22, 2009
    Assignee: Massachusetts Institute of Technology
    Inventors: H. Robert Horvitz, Eric A. Miska, Ezequiel A. Alvarez-Saavedra
  • Solution-based methods for RNA expression profiling
    Publication number: 20070065844
    Abstract: The present invention is directed to novel high-throughput, low-cost, and flexible solution-based methods for RNA expression profiling, including expression of microRNAs and mRNAs.
    Type: Application
    Filed: June 8, 2006
    Publication date: March 22, 2007
    Applicants: Massachusetts Institute of Technology, Dana-Farber Cancer Institute, Inc.,
    Inventors: Todd Golub, Justin Lamb, David Peck, Jun Lu, Eric Miska
  • High throughput methods relating to microRNA expression analysis
    Publication number: 20060019286
    Abstract: The invention relates to methods and compositions for microRNA expression analysis using microarrays.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 26, 2006
    Inventors: H. Horvitz, Eric Miska, Ezequiel Alvarez-Saavedra