Abstract: The present invention provides a method of preparing a lipid nanoparticle dispersion using a twin screw extruder. The inventive lipid nanoparticle dispersion includes greater than 25% lipophilic content in the form of lipidic nanoparticles with volume average particle size less than 120 nm dispersed in a continuous aqueous matrix with greater than 0.1 percent of tetrahydrocannabinol.

Abstract: The present invention provides a nanoparticle dispersion for topical delivery to skin of a mammal. The nanoparticle dispersion includes: one or more hydrophobic bioactive agents or one or more hydrophobic drugs; one or more surfactants; one or more water immiscible oils; and water. Methods of preparing nanoparticle dispersions by hot melt extrusion are also provided.

Abstract: The present invention provides nanoparticle dispersion for topical delivery to skin of a mammal. The nanoparticle dispersion includes: a sorbitan ester surfactant; one or more poly(ethoxylate) surfactants, one or more lipids; and ibuprofen. Methods of preparing various water continuous dispersion of nanoparticles are also provided.

Abstract: The present invention provides a water continuous dispersion of nanoparticles. The water continuous dispersion includes: one or more aromatic amide anesthetic compounds; one or more polyethoxylated high HLB surfactants; one or more low HLB surfactants; one or more oils, wherein one or more nanoparticles of a dispersed phase include a lipid bilayer, and wherein ratio of oil to surfactant is between about 0.12:1 to about 3.5:1. Methods of preparing various water continuous dispersion of nanoparticles are also provided.

Abstract: The present invention provides a water continuous dispersion of nanoparticles including Ibuprofen; one or more high HLB surfactants; one or more low HLB surfactants; and one or more oils. Methods of preparing various water continuous dispersion of nanoparticles are also provided.

Abstract: A progressive cavity pump system on a well includes a holdback apparatus. The holdback apparatus has a housing and a one-way bearing in the housing. The housing attaches to the drive head on the well. The one-way bearing allows the motor to drive the pump. The one-way bearing prevents reverse rotation, preventing the sucker rod from unwinding and fluid above the pump from draining, when the pump loses power.

Abstract: The present invention provides a water continuous dispersion of nanoparticles including Ibuprofen; one or more high HLB surfactants; one or more low HLB surfactants; and one or more oils. Methods of preparing various water continuous dispersion of nanoparticles are also provided.

Abstract: A progressive cavity pump system on a well includes a holdback apparatus. The holdback apparatus has a housing and a one-way bearing in the housing. The housing attaches to the drive head on the well. The one-way bearing allows the motor to drive the pump. The one-way bearing prevents reverse rotation, preventing the sucker rod from unwinding and fluid above the pump from draining, when the pump loses power.

Abstract: A circuit interruption device includes at least one constriction zone. The constriction zone provides for interference with arcing of an electrical signal. The device may include at least one expansion zone. The device may include at least one movable component to assist in creation of the at least one constriction zone. A method of fabrication is provided.

Abstract: The present invention provides a niosomal composition having including: one or more high Kow pharmacologically active compounds; one or more water immiscible oils; one or more low HLB surfactants; one or more polyethoxylated high HLB surfactants; water, and wherein the niosomal composition includes an external phase and a dispersed phase, the particles of the dispersed phase including an oil swollen lipid bilayer. Methods of preparing niosomal compositions by hydration of lamellar phase microemulsions and methods of using these compositions to treat various disorders in a patient in need thereof are also provided.

Abstract: A circuit interruption device includes at least one constriction zone. The constriction zone provides for interference with arcing of an electrical signal. The device may include at least one expansion zone. The device may include at least one movable component to assist in creation of the at least one constriction zone. A method of fabrication is provided.

Abstract: A circuit interruption device includes at least one constriction zone. The constriction zone provides for interference with arcing of an electrical signal. The device may include at least one expansion zone. The device may include at least one movable component to assist in creation of the at least one constriction zone. A method of fabrication is provided.

Abstract: A circuit interruption device includes at least one constriction zone. The constriction zone provides for interference with arcing of an electrical signal. The device may include at least one expansion zone. The device may include at least one movable component to assist in creation of the at least one constriction zone. A method of fabrication is provided.

Abstract: Connectors for modular framing systems having T-shaped slots are disclosed. The connectors connect framing members to each other or connect floor panels to framing members. Architectural structures and modular framing systems containing the connectors are also disclosed.

Abstract: The passage of a container along a conveyor is lubricated by applying to the container or conveyor a composition comprising a water-miscible silicone material wherein the composition comprises a stoichiometric amount of an organic acid. The compatibility of the lubricating composition with polyethylene terephthalate is increased because of the presence of a stoichiometric amount of acid.

Abstract: The passage of a container along a conveyor is lubricated by applying to the container or conveyor a composition comprising a water-miscible silicone material wherein the composition has good wetting to polyethylene terephthalate surfaces. The compatibility of the lubricating composition with polyethylene terephthalate is increased because the wetting of the composition to polyethylene terephthalate is improved.

Abstract: The passage of a container along a conveyor is lubricated by applying to the container or conveyor a lubricant composition comprising a water-miscible silicone material having a silicone emulsion wherein the silicone emulsion contains less than 500 ppm of a triethanolamine salts of alkyl benzene sulfonic acid compounds.

Abstract: The passage of a container along a conveyor is lubricated by applying to the container or conveyor a mixture of a water-miscible silicone material and a water-miscible lubricant. The mixture can be applied in relatively low amounts, to provide thin, substantially non-dripping lubricating films. In contrast to dilute aqueous lubricants, the lubricants of the invention provide drier lubrication of the conveyors and containers, a cleaner conveyor line and reduced lubricant usage, thereby reducing waste, cleanup and disposal problems.

Abstract: Improved organophotoreceptor comprises an electrically conductive substrate and a photoconductive element on the electrically conductive substrate, the photoconductive element comprising: (a) a charge transport material having the formula X-Z-X? where X and X? are, each independently, a (9-fluorenylidene)malononitrile group, and Z is a linking group; and (b) a charge generating compound. Corresponding electrophotographic apparatuses and imaging methods are described.

Abstract: A liquid ink comprises (a) a carrier liquid having a Kauri-Butanol number less than 30; (b) a graft copolymer comprising a (co)polymeric steric stabilizer covalently bonded to a thermoplastic (co)polymeric core that is insoluble in the carrier liquid; and (c) a colorant, wherein the steric stabilizer comprises units derived from 3,3,5-trimethylcyclohexyl methacrylate, and the thermoplastic (co)polymeric core comprising units derived from at least a polymerizable monomer selected from the group consisting of (meth)acrylates having aliphatic amino radicals, nitrogen-containing heterocyclic vinyl monomers, N-vinyl substituted ring-like amide monomers, aromatic substituted ethylene monomers containing amino radicals, and nitrogen-containing vinylether monomers. The organosol provides improved liquid electrophotographic and electrographic ink compositions with improved dispersion stability, chargeability, and blocking resistance so that improved print quality or ink transfer performance are obtained.