Patents by Inventor Eric Murtfeldt

Eric Murtfeldt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEOSIDE TRIPHOSPHATES WITH MODIFIED PHOSPHATE CHAINS, AND METHODS OF SYNTHESIZING THE SAME
    Publication number: 20240317793
    Abstract: In some examples, a nucleoside triphosphate analogue may include a sugar, a nucleobase coupled to the sugar, a triphosphate group coupled to the sugar, a heteroatom coupled to an alpha phosphate of the triphosphate group, and a first substituent coupled to the heteroatom. The heteroatom may be selected from the group consisting of oxygen, nitrogen, and carbon. The first substituent may include at least one of an alkyl chain or a polymer.
    Type: Application
    Filed: March 18, 2024
    Publication date: September 26, 2024
    Applicant: Illumina, Inc.
    Inventors: Hassan Bohra, Xiangyuan Yang, Ramesh Neelakandan, Yin Nah Teo, Abdul Sadeer Abd Salam, Eric Murtfeldt
  • Polymerases, compositions, and methods of use
    Patent number: 12077789
    Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain low pre-phasing rates when using ambiently stored polymerases, as well as methods and kits using the same.
    Type: Grant
    Filed: June 1, 2022
    Date of Patent: September 3, 2024
    Assignee: ILLUMINA, INC.
    Inventors: Misha Golynskiy, Mariko Matsuura, Saurabh Nirantar, Hamed Tabatabaei Ghomi, Seth McDonald, Ryan Craig, Sergio Peisajovich, Kyrie Johnson, Kay Klausing, Eric Murtfeldt, Alexandra Exner
  • POLYMERASES, COMPOSITIONS, AND METHODS OF USE
    Publication number: 20240141427
    Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain low error rate, low phasing rate, or increased incorporation rate for a second generation ffN under reduced incorporation times, as well as methods and kits using the same.
    Type: Application
    Filed: September 27, 2023
    Publication date: May 2, 2024
    Applicant: ILLUMINA, INC.
    Inventors: Misha Golynskiy, Rahman Rahman Pour, Jiawen Li, Ryan Craig, Hamed Tabatabaei Ghomi, Saurabh Nirantar, Hsu Myat Noe, Lin Hui Chang, Yvonne Devadas, Jing Wen Lim, Kay Klausing, Humberto Rojo, Eric Murtfeldt, Chris Garcia
  • Compositions and Methods for Assessing DNA Damage in a Library and Normalizing Amplicon Size Bias
    Publication number: 20240026431
    Abstract: Described herein are standards and methods of normalizing amplicon size bias. These standards may comprise unique molecular identifiers. In some embodiments, the standards and methods are for use with next generation sequencing (NGS) assays. Also described herein are methods for quantifying DNA damage in a sample comprising DNA using fluorescence or for determining the presence of DNA damage in a library.
    Type: Application
    Filed: September 25, 2023
    Publication date: January 25, 2024
    Applicant: Illumina, Inc.
    Inventors: Andrew B. Kennedy, Lena Storms, Fei Shen, Olivia Benice, Eric Murtfeldt, Kaitlin Pugliese, Michael Howard
  • POLYMERASES, COMPOSITIONS, AND METHODS OF USE
    Publication number: 20230047225
    Abstract: Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain low pre-phasing rates when using ambiently stored polymerases, as well as methods and kits using the same.
    Type: Application
    Filed: June 1, 2022
    Publication date: February 16, 2023
    Applicants: ILLUMINA, INC., ILLUMINA CAMBRIDGE LIMITED, ILLUMINA SINGAPORE PTE. LTD.
    Inventors: Misha Golynskiy, Mariko Matsuura, Saurabh Nirantar, Hamed Tabatabaei Ghomi, Seth McDonald, Ryan Craig, Sergio Peisajovich, Kyrie Johnson, Kay Klausing, Eric Murtfeldt, Alexandra Exner