Abstract: Disclosed herein is an electroporation system including a catheter shaft, at least one electrode coupled to the catheter shaft at a distal end thereof, and an electroporation generator coupled in communication with the at least one electrode. The electroporation generator configured to supply a biphasic pulse signal to the at least one electrode. The biphasic pulse signal includes a first phase having a first polarity and a first pulse duration, and a second phase having a second polarity opposite to the first polarity, and a second pulse duration. Each of the first phase and second phase has a voltage amplitude of at least 500 volts and a pulse duration of less than 20 microseconds. The second phase is generated at a non-zero interval following the first phase.

Abstract: A rotorcraft includes a drive shaft coupled to an engine; a sprag clutch coupled the drive shaft; and an output shaft coupled to the sprag clutch, wherein the sprag clutch physically contacts a first contact surface of the output shaft during operation, wherein a first cross-sectional thickness of the output shaft near the middle of the first contact surface is greater than a second cross-sectional thickness of the output shaft near a first edge of the first contact surface.

Abstract: A vocational vehicle includes a chassis, a cab supported by the chassis, a body supported by the chassis and defining a compartment, a lift assembly coupled to the body so that the lift assembly is configured to move between a lowered position and a raised position along a path, a sensor defining a field of view that at least partially includes the path of the lift assembly, and a vehicle control system in communication with the lift assembly and the sensor. The vehicle control system includes a controller having a processor and at least one memory. The controller is configured to detect that the lift assembly is activated to move and disable the sensor.

Abstract: CRISPR/Cas9-mediated genome editing holds clinical potential for treating genetic diseases, such as Duchenne muscular dystrophy (DMD), which is caused by mutations in the dystrophin gene. Here, an improved variant of SpCas9 is provided that exhibits increase capacity to target genomic loci and drive CRISPR-mediated gene editing and a higher efficiency, particular for the treatment of DMD.

Abstract: Compositions for treatment of discogenic pain are discussed herein. In various embodiments, the composition includes PMMA microparticles, Pluronic® surfactant, PBS, and a radio marker. In some embodiments, the PMMA microparticles have a particle size distribution between 25-125 microns and are nonlinearly cross-linked. The composition may be stored at a cooled temperature and upon injection, the composition warms and transitions to a gel state. The composition may also include about 50% PMMA microparticles, about 10% Pluronic®, about 30% PBS, and about 10% of a radio marker.

Abstract: A system includes a refuse vehicle, multiple refuse containers, and a remote computing system. The refuse vehicle includes a telematics unit. The refuse containers are positioned at different customer locations. Each of the refuse containers include a sensor configured to measure a fill level and a wireless transceiver. The remote computing system includes processing circuitry configured to obtain a status of the refuse vehicle from the telematics unit. The processing circuitry is also configured to obtain sensor data from the refuse containers indicating the fill level of each of the refuse containers. The processing circuitry is also configured to determine a route for the refuse vehicle based on the status of the refuse vehicle and the sensor data obtained from the refuse containers. The processing circuitry is also configured to transmit the route to the telematics unit of the refuse vehicle.

Abstract: A refuse vehicle, comprising a chassis, a user input device, at least one tractive element, at least one sensor for receiving sensor data related to the surrounding environment, and at least one processor. The processor receives the sensor data and processes it to identify non-drivable bounding areas. Additionally, the processor receives an indication from the user input device to autonomously operate the vehicle in reverse. In response to this indication, the processor autonomously adjusts one or more operating parameters to operate the vehicle in reverse and avoid the non-drivable bounding areas.

Abstract: A includes a camera and processing circuitry. The camera can be oriented outwards from the refuse vehicle and is configured to obtain image data of a refuse container. The processing circuitry can be configured to obtain the image data. The processing circuitry can also configured to predict, based on the image data, a type of refuse in the refuse container. The processing circuitry can also be configured to, responsive to determining that the refuse vehicle is configured to collect the type of refuse in the refuse container, operate a lift apparatus of the refuse vehicle to empty the refuse in the refuse container into a hopper of the refuse vehicle.

Abstract: A system for monitoring an operation of a refuse vehicle includes a device configured to collect data pertaining to operations of the refuse vehicle and a performance of an operator, and one or more processing circuits in communication with the device. The one or more processing circuits are configured to receive, from the device, the data pertaining to operations of the refuse vehicle and the performance of the operator, analyze the data based on baseline data, the baseline data pertaining to a baseline value of the operations of the refuse vehicle and the performance of the operator, generate, based on an analysis of the data, an operator score, and provide, via a display, a user interface that includes the operator score.

Abstract: A refuse vehicle includes a chassis a body assembly coupled to the chassis, the body assembly including a tailgate and a refuse compartment, the tailgate pivotably coupled with the refuse compartment and positioned at a rear of the refuse compartment, and a spray system coupled to the body assembly and configured to selectively activate to spray a fluid at a target, the target including at least one of the tailgate or the refuse compartment.

Abstract: A refuse vehicle includes a body, a hopper, a robotic arm implement, multiple cameras, and processing circuitry. The body defines a pair of refuse compartments. The hopper receives refuse and direct the refuse into one of the pair of refuse compartments. The cameras are positioned at the hopper. The processing circuitry obtains image data of the hopper from the cameras. The processing circuitry detects an object to be separated from other refuse in the hopper based on the image data. The processing circuitry is also configured to operate the robotic arm implement to move the object from a first part of the hopper to a second part of the hopper for storage in one of the pair of refuse compartments separate from other refuse. The processing circuitry may be configured to obtain at least part of the image data from a camera positioned within a customer's refuse container.

Abstract: A refuse vehicle includes a chassis, a body coupled to the chassis, a compaction system, a camera, and one or more processing circuits. The body defines a refuse compartment configured to store refuse therein. The one or more processing circuits are configured to acquire, from the camera, image data corresponding to an object associated with refuse acquired by the refuse vehicle, determine, based on the image data, a refuse category associated with the object, determine, based on the refuse category, a first packing profile for the compaction system, and operate the compaction system according to the first packing profile. The first packing profile includes at least one packing parameter associated with operation of the compaction system.

Abstract: A refuse vehicle includes a chassis, a body coupled to the chassis and defining a refuse compartment, a lift assembly configured to lift a refuse container to dump contents thereof into the refuse compartment, a display interface, a plurality of cameras positioned to capture a plurality of different views from the refuse vehicle, and a controller. The controller is configured to assign priority values to the plurality of different views, compare the priority values, and display, on the display interface, at least one of the plurality of different views based on the comparison of the priority values.

Abstract: 1. A system for detecting a refuse can including at least one sensor and one or more processing circuits communicably coupled to the sensor. The one or more processing circuits are configured to capture, from the at least one sensor, data regarding a pickup location associated with a refuse can, determine, based on the data, if the refuse can is present at the pickup location, upon determining that the refuse can is absent from the pickup location, generate an indication that the refuse can is absent from the pickup location, and upon determining that the refuse can is present at the pickup location, generate a command to initiate a refuse collection operation.

Abstract: A refuse vehicle includes a chassis, a body coupled to the chassis and defining a refuse compartment, a tailgate pivotally coupled to the body at a rear of the refuse compartment, a first camera coupled to the tailgate at a first location, a second camera coupled to the tailgate at a second location lower than the first location, and a controller. The controller is configured to detect a reverse operation of the refuse vehicle, cause the first camera to capture a first image during the reverse operation when the tailgate is at a closed position, and cause the second camera to capture a second image during the reverse operation when the tailgate is at a fully open position.

Abstract: A refuse collection system includes a deployable refuse collection vehicle and a control system. The deployable refuse collection vehicle is configured to deploy from a refuse vehicle. The deployable refuse collection vehicle includes a chassis, a drive system coupled to the chassis, one or more sensors configured to acquire data to facilitate detecting a refuse can, a grip apparatus configured to engage the refuse can. The control system is configured to detect the refuse can based on the data, control the drive system to navigate the deployable refuse collection vehicle to the refuse can, and control the grip apparatus to engage with the refuse can.

Abstract: A system for directing vehicles in a refuse transfer station comprising: an electronic device; a communication hub; and one or more processors configured to: receive an indication from the electronic device of a first location of at least one object and a second location of at least one vehicle; map the location of the first location and the second location; determine a path between the first location and the second location; and transmit, through the communication hub, to the at least one vehicle the path between the first location and the second location.