Patents by Inventor Eric P. Brass

Eric P. Brass has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides and methods for inducing cell death
    Patent number: 9562083
    Abstract: The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein. In some aspects, the method can be used in the diagnosis, prevention, or treatment of a disease, such as an infection, cancer, autoimmune disease, or inflammatory disease.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: February 7, 2017
    Assignee: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
    Inventors: Michael R. Yeaman, Nannette Y. Yount, Eric P. Brass
  • PEPTIDES AND METHODS FOR INDUCING CELL DEATH
    Publication number: 20150232521
    Abstract: The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein. In some aspects, the method can be used in the diagnosis, prevention, or treatment of a disease, such as an infection, cancer, autoimmune disease, or inflammatory disease.
    Type: Application
    Filed: January 29, 2015
    Publication date: August 20, 2015
    Inventors: Michael R. YEAMAN, Nannette Y. YOUNT, Eric P. BRASS
  • PEPTIDES AND METHODS FOR INDUCING CELL DEATH
    Publication number: 20140227767
    Abstract: The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein. In some aspects, the method can be used in the diagnosis, prevention, or treatment of a disease, such as an infection, cancer, autoimmune disease, or inflammatory disease.
    Type: Application
    Filed: May 1, 2013
    Publication date: August 14, 2014
    Inventors: Michael R. YEAMAN, Nannette Y. YOUNT, Eric P. BRASS
  • Multifunctional context-activated protides and methods of use
    Patent number: 8592375
    Abstract: This invention is directed to multifunctional, context-activated protides that have two or more effectors with individually distinct biological functions and one or more corresponding activator sites that can each initiate or amplify the biological function of one or more effectors upon context-activation. The context-activated protides of the invention are useful in the diagnosis, prophylaxis, and therapy of a broad range of pathological conditions.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: November 26, 2013
    Assignee: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
    Inventors: Michael R. Yeaman, Nannette Y. Yount, John E. Edwards, Jr., Eric P. Brass
  • Peptides and methods for inducing cell death
    Patent number: 8492333
    Abstract: The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein. In some aspects, the method can be used in the diagnosis, prevention, or treatment of a disease, such as an infection, cancer, autoimmune disease, or inflammatory disease.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: July 23, 2013
    Assignee: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
    Inventors: Michael R. Yeaman, Nannette Y. Yount, Eric P. Brass
  • Peptides and methods for inducing cell death
    Publication number: 20110288006
    Abstract: The invention provide isolated peptides, protides and conjugates having novel peptide sequences which are able to induce antimicrobial, anti-cancer, anti-inflammatory, anti-proliferative or programmed cell death activity. The invention also provides a method of inducing programmed cell death in a cell by contacting the cell with an isolated peptide, protide or conjugate described herein. In some aspects, the method can be used in the diagnosis, prevention, or treatment of a disease, such as an infection, cancer, autoimmune disease, or inflammatory disease.
    Type: Application
    Filed: February 22, 2011
    Publication date: November 24, 2011
    Applicant: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
    Inventors: Michael R. Yeaman, Nannette Y. Yount, Eric P. Brass
  • Multifunctional context-activated protides and methods of use
    Patent number: 7067621
    Abstract: This invention is directed to multifunctional, context-activated protides that have two or more effectors with individually distinct biological functions and one or more corresponding activator sites that can each initiate or amplify the biological function of one or more effectors upon context-activation. The context-activated protides of the invention are useful in the diagnosis, prophylaxis, and therapy of a broad range of pathological conditions.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: June 27, 2006
    Assignee: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
    Inventors: Michael R. Yeaman, Nannette Y. Yount, John E. Edwards, Jr., Eric P. Brass