Abstract: The invention involves the provision of recombinant algal mutants that have a genetic modification to a nucleic acid sequence encoding a trehalose biosynthetic enzyme, and/or a genetic modification to a nucleic acid encoding an RNA binding domain And in some embodiments either of these algal mutants can further have a genetic mutation to a nucleic acid sequence encoding an SGI1 polypeptide. Attenuation of one, two, or all three of these genes results in a mutant organism with increased lipid productivity. It was also discovered that one, two, three, or more genetic mutations can be accumulated or “stacked” in a particular mutant cell or organism to result in further increases in the production of lipid products. The lipid products of these mutants are useful as biofuels or for other specialty chemical products.

Abstract: A spinal implant template includes a shaft extending along an axis between a proximal end and a distal end. An engagement portion is configured for insertion between vertebrae of a patient. The engagement portion includes a rod extending from the distal end at an acute angle relative to the longitudinal axis to facilitate ease of entry around a spinal cord of the patient. Systems, surgical instruments, spinal implants and methods are disclosed.

Abstract: A spinal implant template includes a shaft extending along an axis between a proximal end and a distal end. An engagement portion is configured for insertion between vertebrae of a patient. The engagement portion includes a rod extending from the distal end at an acute angle relative to the longitudinal axis to facilitate ease of entry around a spinal cord of the patient. Systems, surgical instruments, spinal implants and methods are disclosed.

Abstract: A surgical instrument includes a body extending between a first end and a second end and includes at least one mating element engageable with an interbody implant. A first member is disposed with the body and engageable with the interbody implant to move the interbody implant between a first configuration and a second, expanded configuration. A second member is disposed with the body and engageable with the interbody implant to fix the interbody implant in a selected second configuration. Systems and methods are disclosed.

Abstract: A system and method for a procedure that can be performed on any appropriate subject. Procedures can include assembling any appropriate work piece or installing members into a work piece, such as an airframe, autoframe, etc. Regardless of the subject, generally the procedure can have a selected result that is efficacious. The efficacious result may be the desired or best result for the procedure. The system and method can be used in confirming a selected result that can be efficacious.

Abstract: A surgical instrument includes a body extending between a first end and a second end and includes at least one mating element engageable with an interbody implant. A first member is disposed with the body and engageable with the interbody implant to move the interbody implant between a first configuration and a second, expanded configuration. A second member is disposed with the body and engageable with the interbody implant to fix the interbody implant in a selected second configuration. Systems and methods are disclosed.

Abstract: A system and method for a procedure that can be performed on any appropriate subject. Procedures can include assembling any appropriate work piece or installing members into a work piece, such as an airframe, autoframe, etc. Regardless of the subject, generally the procedure can have a selected result that is efficacious. The efficacious result may be the desired or best result for the procedure. The system and method can be used in confirming a selected result that can be efficacious.

Abstract: A system and method for a procedure that can be performed on any appropriate subject. Procedures can include assembling any appropriate work piece or installing members into a work piece, such as an airframe, autoframe, etc. Regardless of the subject, generally the procedure can have a selected result that is efficacious. The efficacious result may be the desired or best result for the procedure. The system and method can be used in confirming a selected result that can be efficacious.

Abstract: Embodiments of the invention include expandable, implantable devices and methods. Devices expand linearly to provide secure fixation between or among anatomical structures. In some embodiments, an implant replaces one or more vertebral bodies of the spine.

Abstract: A motion-sensing mechanism is provided that facilitates numerous aspects of the medical industry. In one aspect, the motion-sensing mechanism is used to track instruments and personnel in a field of view relative to a patient such that the instrument or personnel may be displayed on a heads-up display showing a model of the patient's anatomy. In another aspect, the motion-sensing mechanism makes a reference image of a patient, visitor, or staff such that when the subject of the reference images passes another (or the same) motion-sensing mechanism, the identity of the subject is determined or recognized. In still other aspects, the motion-sensing mechanism monitors motion of a portion of a patient's anatomy and compares the same to an expected motion for diagnostic evaluation of pain generators, physical therapy effectiveness, and the like.

Abstract: An expandable medical implant for supporting bone structures includes a curved outer member to cooperatively engage a first bone structure and a curved inner member configured to cooperatively engage a second bone structure. The curved inner member is receivable within and movable relative to the curved outer member along an arc bounded by the curvature of the curved outer member. One of the curved outer and inner members may include a tapered surface and the other of the curved outer and inner members may include a scalloped surface. The implant may include a locking element disposed between the tapered and scalloped surface. The locking element is movable between a locked position engaging the tapered surface and a roughened locking surface to inhibit a decrease in the overall height of the implant and an unlocked position permitting at least an increase in the overall height of the implant.

Abstract: Embodiments of the invention include expandable, implantable devices and methods. Devices expand linearly to provide secure fixation between or among anatomical structures. In some embodiments, an implant replaces one or more vertebral bodies of the spine.

Abstract: An expandable medical implant for supporting bone structures is disclosed. The implant may include an outer member and an inner member receivable in the outer member. One of the outer and inner members includes a tapered surface and the other of the outer and inner members includes a scalloped surface. The implant may also include a locking element disposed between the tapered surface and the scalloped surface. The tapered surface may be movable relative to the locking element to transversely shift the locking element into engagement with the scalloped surface to inhibit a decrease in the overall implant height.

Abstract: Implants sized to be inserted into an intervertebral space between first and second vertebral members. The implants may include a body with opposing first and second ends. An end cap may be connected to the body and include a first side with a contact surface that faces away from the body and is configured to contact against one of the first and second vertebral members when the implant is positioned in the intervertebral space. The end cap may also include a second side that faces towards the body. A connection mechanism may connect the end cap and the body for the end cap to pivot to adjust an angular position of the end cap relative to the body. The body and the end cap may each include locking features that engage together to lock an angular position of the end cap. The locking features may be configured to overlap at each of the angular positions to engage together and maintain the angular position of the end cap relative to the body when the implant is positioned in the intervertebral space.

Abstract: A system and method for a procedure that can be performed on any appropriate subject. Procedures can include assembling any appropriate work piece or installing members into a work piece, such as an airframe, autoframe, etc. Regardless of the subject, generally the procedure can have a selected result that is efficacious. The efficacious result may be the desired or best result for the procedure. The system and method can be used in confirming a selected result that can be efficacious.

Abstract: Embodiments of the invention include expandable, implantable devices and methods. Devices expand linearly to provide secure fixation between or among anatomical structures. In some embodiments, an implant replaces one or more vertebral bodies of the spine.

Abstract: Embodiments of the invention include expandable, implantable devices and methods. Devices expand linearly to provide secure fixation between or among anatomical structures. In some embodiments, an implant replaces one or more vertebral bodies of the spine.

Abstract: Embodiments of the invention include expandable, implantable devices and methods. Devices expand linearly to provide secure fixation between or among anatomical structures. In some embodiments, an implant replaces one or more vertebral bodies of the spine.

Abstract: An expandable medical implant for supporting skeletal structures. The medical implant having a length along its expandable dimension. The implant having a first tubular member with a connection end, an opposite skeletal interface end, and a central expansion instrument opening. Also, the implant has a second tubular member with a connection end configured to engage with the connection end of the first tubular member. The second tubular member having an opposite skeletal interface end. Additionally, an expansion instrument is insertable through the central expansion instrument opening and expandable against the first tubular member and the connection end of the second tubular member to expand the medical implant. The combined first and second tubular members are of a greater dimension along the length of the implant than the combined first and second tubular members are in any dimension perpendicular to their length.

Abstract: Implants sized to be inserted into an intervertebral space between first and second vertebral members. The implants may include a body with opposing first and second ends. An end cap may be connected to the body and include a first side with a contact surface that faces away from the body and is configured to contact against one of the first and second vertebral members when the implant is positioned in the intervertebral space. The end cap may also include a second side that faces towards the body. A connection mechanism may connect the end cap and the body for the end cap to pivot to adjust an angular position of the end cap relative to the body. The body and the end cap may each include locking features that engage together to lock an angular position of the end cap. The locking features may be configured to overlap at each of the angular positions to engage together and maintain the angular position of the end cap relative to the body when the implant is positioned in the intervertebral space.