Patents by Inventor Eric POZSGAI

Eric POZSGAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systemic delivery of adeno-associated virus vector expressing gamma-sarcoglycan and the treatment of muscular dystrophy
    Patent number: 11925675
    Abstract: Described herein are methods of treating muscular dystrophy comprising administering to a subject a recombinant AAV (rAAV) scAAVrh74.MHCK7.hSGCG vector, methods of expressing gamma-sarcoglycan gene in a patient, pharmaceutical compositions comprising the rAAV scAAVrh74.MHCK7.hSGCG for usage in such methods, the doses and the ranges thereof for such methods, and methods of generating and producing the rAAV scAAVrh74.MHCK7.hSGCG.
    Type: Grant
    Filed: September 7, 2021
    Date of Patent: March 12, 2024
    Assignee: Sarepta Therapeutics, Inc.
    Inventors: Louise Rodino-Klapac, Eric Pozsgai
  • COMPOSITIONS AND METHODS FOR RESTORING AND MAINTAINING THE DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX (DAPC)
    Publication number: 20230040544
    Abstract: Disclosed herein are methods of repairing or restoring a sarcoglycan complex or DAPC, stabilizing DAPC, restoring DAPC function, or increasing or enhancing expression of one or more components of a sarcoglycan complex or DAPC in a subject suffering from a muscular dystrophy.
    Type: Application
    Filed: December 15, 2020
    Publication date: February 9, 2023
    Inventors: Eric Pozsgai, Louise Rodino-Klapac
  • SYSTEMIC DELIVERY OF ADENO-ASSOCIATED VIRUS VECTOR EXPRESSING GAMMA-SARCOGLYCAN AND THE TREATMENT OF MUSCULAR DYSTROPHY
    Publication number: 20220088123
    Abstract: Described herein are methods of treating muscular dystrophy comprising administering a recombinant AAV (rAAV) scAAVrh74.MHCK7.hSGCG vector, methods of expressing gamma-sarcoglycan gene in a patient, pharmaceutical compositions comprising the rAAV, and methods of generating the rAAV.
    Type: Application
    Filed: September 7, 2021
    Publication date: March 24, 2022
    Inventors: Louise RODINO-KLAPAC, Eric POZSGAI