Abstract: The present disclosure relates to an oral, extended release, abuse deterrent dosage form containing a controlled release agent, a second agent and/or polyethylene glycol, and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is stable at high temperatures and abuse deterrent to oral and parenteral administration via dose dumping, extraction, and purification. The present disclosure also relates to processes of preparing the dosage form.

Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent liquid filled capsule containing polyethylene glycol and at least one active pharmaceutical ingredient susceptible to abuse. The dosage form is abuse deterrent to parenteral administration. The present disclosure also relates to processes of preparing the dosage form.

Abstract: An apparatus and method for unfreezing a window from a window seal are disclosed. According to some embodiments of the present disclosure, the apparatus includes a vehicle door assembly including a vehicle door and a window. The apparatus further includes a window seal that receives an upper edge of the window and a heating element coupled to the upper edge or the window seal. The system further includes a power source that provides an electrical current to the heating element and a control module configured to receive a remote unlock signal from a remote device, obtain a temperature signal indicating a temperature in response to the remote unlock signal, compare the temperature indicated by the temperature signal to a temperature threshold, and cause the power source to provide the electrical current to the heating element when the temperature is less than the temperature threshold.

Abstract: The present disclosure relates to an oral, extended release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a matrix used to deter abuse. The pill can be prepared using a hot melt extrusion process and a forming unit. The formed pill meets regulatory guidelines for extended release formulations and is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.

Abstract: The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.

Abstract: The invention relates to the field of depositing agents on surfaces using highly volatile silicone solvents. Particularly, the invention relates to novel compositions useful for depositing agents on skin and other surfaces.

Abstract: An apparatus and method for unfreezing a window from a window seal are disclosed. According to some embodiments of the present disclosure, the apparatus includes a vehicle door assembly including a vehicle door and a window. The apparatus further includes a window seal that receives an upper edge of the window and a heating element coupled to the upper edge or the window seal. The system further includes a power source that provides an electrical current to the heating element and a control module configured to receive a remote unlock signal from a remote device, obtain a temperature signal indicating a temperature in response to the remote unlock signal, compare the temperature indicated by the temperature signal to a temperature threshold, and cause the power source to provide the electrical current to the heating element when the temperature is less than the temperature threshold.