Abstract: A method of preventing paravalvular leakage includes concurrent delivery of a heart valve prosthesis and an annular sealing component. During delivery, the sealing component is moved from a first position to a second position of the heart valve prosthesis which is longitudinally spaced apart from the first position of the heart valve prosthesis. The sealing component is secured around the heart valve prosthesis at the second position by a contoured outer surface of the heart valve prosthesis. The sealing component may be a flexible ring or may be a cylindrical flexible sleeve having a plurality of ribs longitudinally extending over the cylindrical sleeve. The ribs operate to deploy the sealing component such that at least a portion of the cylindrical sleeve buckles outwardly away from the outer surface of the heart valve prosthesis.

Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.

Abstract: Systems and methods for broadcasting a video stream are disclosed. The systems and methods can receive a video stream from a broadcaster, process the video steam, store the video streaming, and deliver the video stream to a viewer as a live video stream or a video on demand. The viewer may use an access token to access the video stream. The systems and methods may include an error detection mechanism for detecting an interrupt in the video stream. The systems and methods can restore the access token to its original state if an error is detected. The systems and methods can also include one or more link sharing mechanisms for sharing links to a video stream. The shareable links may be associated with share tokens.

Abstract: A method of preventing paravalvular leakage includes concurrent delivery of a heart valve prosthesis and an annular sealing component. During delivery, the sealing component is moved from a first position to a second position of the heart valve prosthesis which is longitudinally spaced apart from the first position of the heart valve prosthesis. The sealing component is secured around the heart valve prosthesis at the second position by a contoured outer surface of the heart valve prosthesis. The sealing component may be a flexible ring or may be a cylindrical flexible sleeve having a plurality of ribs longitudinally extending over the cylindrical sleeve. The ribs operate to deploy the sealing component such that at least a portion of the cylindrical sleeve buckles outwardly away from the outer surface of the heart valve prosthesis.

Abstract: Medication packaging includes a body defining a cavity for disposal of medication. A closure member is disposed with the body. The closure member includes an advancement mechanism and a window that displays indicia of a medication dosage regimen. The closure member is rotatable between a medication accessible configuration and a closed configuration that includes a sealing position and an advance position to incrementally advance the indicia. Systems and methods of use are disclosed.

Abstract: A medicament dispensing container includes a first wall connected with a second wall and defines a cavity therebetween. The walls are movable between an open configuration and a closed configuration. At least one member is disposable in the cavity and defines at least one dose receptacle configured for disposal of at least one dose of at least one medication. At least one fixation member connects the at least one member to at least one of the walls such that the at least one member is movable relative to the wall. Systems and methods of use are disclosed.

Abstract: Systems and methods for broadcasting a video stream are disclosed. The systems and methods can receive a video stream from a broadcaster, process the video steam, store the video streaming, and deliver the video stream to a viewer as a live video stream or a video on demand. The viewer may use an access token to access the video stream. The systems and methods may include an error detection mechanism for detecting an interrupt in the video stream. The systems and methods can restore the access token to its original state if an error is detected. The systems and methods can also include one or more link sharing mechanisms for sharing links to a video stream. The shareable links may be associated with share tokens.

Abstract: Medication packaging includes a housing. A medication container is attached with the housing by a tether. The medication container is engageable with the housing between a child resistant configuration and a medication accessible configuration. Systems and methods of use are disclosed.

Abstract: A medicament dispensing container includes a first wall connected with a second wall and defines a cavity therebetween. The walls are movable between an open configuration and a closed configuration. At least one member is disposable in the cavity and defines at least one dose receptacle configured for disposal of at least one dose of at least one medication. At least one fixation member connects the at least one member to at least one of the walls such that the at least one member is movable relative to the wall. Systems and methods of use are disclosed.

Abstract: A personal electronic device case, and method for making such personal electronic device case, created by a method of bonding a resin-type material to a selected material otherwise unsuitable for protection of a personal electronic device, and carving the resulting composition into a desired shape of personal electronic device case. The resulting phone case is both aesthetically pleasing and offers improved protection for the personal electronic device.

Abstract: Systems and methods for broadcasting a video stream are disclosed. The systems and methods can receive a video stream from a broadcaster, process the video steam, store the video streaming, and deliver the video stream to a viewer as a live video stream or a video on demand. The viewer may use an access token to access the video stream. The systems and methods may include an error detection mechanism for detecting an interrupt in the video stream. The systems and methods can restore the access token to its original state if an error is detected. The systems and methods can also include one or more link sharing mechanisms for sharing links to a video stream. The shareable links may be associated with share tokens.

Abstract: A method for evaluating the depth of a burn wound in a subject comprises (a) receiving an imaging video of the burn wound collected by an ultrasound transducer, (b) evaluating nodes and edges connecting the nodes in a plurality of layers of the burn wound in a plurality of frames of the imaging video, with a classifier system, the classifier system comprising a convolutional neural network that compares the nodes and edges of the burn wound with nodes and edges in a plurality of layers of a plurality of historical burn wounds of known depth, and (c) assigning a depth to the burn wound, the assigned depth being an average of depths associated with a plurality of the historical burn wounds having a predetermined minimum similarity of nodes and edges to the nodes and edges of the burn wound.

Abstract: Medication packaging includes a body defining a cavity for disposal of medication. A closure member is disposed with the body. The closure member includes an advancement mechanism and a window that displays indicia of a medication dosage regimen. The closure member is rotatable between a medication accessible configuration and a closed configuration that includes a sealing position and an advance position to incrementally advance the indicia. Systems and methods of use are disclosed.

Abstract: A medicament dispensing container includes a first wall connected with a second wall and defines a cavity therebetween. The walls are movable between an open configuration and a closed configuration. At least one member is disposable in the cavity and defines at least one dose receptacle configured for disposal of at least one dose of at least one medication. At least one fixation member connects the at least one member to at least one of the walls such that the at least one member is movable relative to the wall. Systems and methods of use are disclosed.

Abstract: A personal electronic device case, and method for making such personal electronic device case, created by a method of bonding a resin-type material to a selected material otherwise unsuitable for protection of a personal electronic device, and carving the resulting composition into a desired shape of personal electronic device case. The resulting phone case is both aesthetically pleasing and offers improved protection for the personal electronic device.

Abstract: A method of preventing paravalvular leakage includes concurrent delivery of a heart valve prosthesis and an annular sealing component. During delivery, the sealing component is moved from a first position to a second position of the heart valve prosthesis which is longitudinally spaced apart from the first position of the heart valve prosthesis. The sealing component is secured around the heart valve prosthesis at the second position by a contoured outer surface of the heart valve prosthesis. The sealing component may be a flexible ring or may be a cylindrical flexible sleeve having a plurality of ribs longitudinally extending over the cylindrical sleeve. The ribs operate to deploy the sealing component such that at least a portion of the cylindrical sleeve buckles outwardly away from the outer surface of the heart valve prosthesis.

Abstract: Methods and apparatus for simulating risk tolerance and associated adversary costs in a distributed business process are disclosed. The methods and apparatus simulate an interdependent business process, such as a financial transaction system, in a secure distributed manner. Each business entity that is part of the interdependent business process models itself on a local client device at any chosen level of detail. A simulation server connects the separate client based simulations into one large simulation. Details of each local simulation may be hidden from other simulation participants. However, interruptions in business flow caused by simulated disruptions introduced at the simulation server and/or a client device are propagated to all of the effected simulation participants via the simulation server. In addition, the simulation server receives inputs from users indicative of risk tolerance levels and associated response actions.

Abstract: The invention relates to a system for testing heart valve leaflets. The system includes a leaflet support assembly with a support post for receiving and supporting a leaflet to be tested, the post being disposed in a target region of the support assembly. The system also has a transmitter assembly that includes a light source and is configured and arranged to direct light from the light source onto the target region. The system further includes a receiver assembly that has an image sensor configured and arranged to sense an image of the target region and generate image information indicative of the sensed image, such as leaflet droop.