Abstract: A display system configured to communicate tissue proximity data from a plurality of electrodes includes a display. The display outputs a circular graphical representation. The circular graphical representation includes a plurality of color areas forming a first circular shape. Each of the color areas communicate a categorized value for a respective electrode indicative of tissue proximity for the respective electrode. A plurality of graph areas form a second circular shape. Each of the graph areas communicate a relative value for the respective electrode indicative of the tissue proximity for the respective electrode.

Abstract: Steerable catheter control handles and catheter assemblies that include pull wires and direction and magnitude controls on the handle operable such that adjustment of the direction and magnitude controls adjusts a direction and degree of catheter flex, thereby to steer the catheter as an operator directs.

Abstract: Provided herein are devices and methods for isolation and detection of an analyte from a sample. In some embodiments, provided herein are devices and methods of use thereof for vertical flow-based isolation and detection of analytes in a liquid sample, such as a urine sample.

Abstract: The present disclosure relates to aerosol delivery devices, methods of forming such devices, and elements of such devices. In some embodiments, the present disclosure provides a heating member that can be formed of a heating element conformed to a heater substrate configured as a truncated cone (or similar shape) having a first end of a first size and a second end of greater size. In some embodiments, the disclosure provides methods of forming an aerosol delivery device, which can include providing a shell, providing a heating member formed of a heating element conformed to a substrate, configuring the heating member as a truncated cone (or similar shape) having a first end of a first size and a second end of greater size, and inserting the heating member within the shell.

Abstract: A wireless system includes memory configured to store information of physical layer rates associated with power levels between a client device and respective access points. The power levels comprise information of amounts of power in signals received by the client device from the respective access points. The system includes one or more processors configured to: during a communication session between the client device and a first access point, determine a current power level between the client device and a second access point, access the information based on the current power level to determine an expected physical layer rate between the client device and the second access point, determine a current physical layer rate between the client device and the first access point, and determine whether to switch the communication session to the second access point based on the expected physical layer rate and the current physical layer rate.

Abstract: The present disclosure relates to methods for detecting unique genetic signatures derived from markers such as, for example, mutations, somatic or germ-line, in nucleic acids obtained from biological samples. The sensitivity of the methods provides for detection of mutations associated with a disease, e.g., cancer mutations, or with inherited disease, e.g., an autosomal recessive disease, in a noninvasive manner at ultra-low proportions of sequences carrying mutations to sequences carrying normal, e.g., non-cancer sequences, or a reference sequence, e.g., a human reference genome.

Abstract: Methods, systems and apparatus for associating electronic devices together based on received audio commands are described. Methods for associating an audio-controlled device with a physically separate display screen device such that information responses can then be provided in both audio and graphic formats using the two devices in conjunction with each other are described. The audio-controlled device can receive audio commands that can be analyzed to determine the author, which can then be used to further streamline the association operation.

Abstract: A valve repair devices and systems for repairing a native valve of a patient include a spacer, a plurality of paddles, and a plurality of moveable clasp arms. The plurality of moveable clasp arms are disposed between the plurality of paddles and the spacer. The moveable clasp arms are configured to attach to leaflets of a heart valve.

Abstract: A method for electronic device virtualization and management includes transmitting a signal to a server from a client. The signal is initiated by a user of a user interface of the client. The user interface of the client presents at least two devices to the user, which the user may interact with. The signal may include a power cycling instruction directed to at least one of the devices. When the server receives a communication back from the at least one device, it may send the information to the client, where the user interface may be updated in response to the communication. The devices may be controlled with other instructions, such as scheduling instructions, firmware update instructions, and configuration backup instructions. If a power device is virtualized, it may be controlled on a port-by-port basis.

Abstract: Methods and apparatus, including computer program products, are provided for remote monitoring. In some example implementations, there is provided a method. The method may include receiving, at a remote monitor, a notification message representative of an event detected, by a server, from analyte sensor data obtained from a receiver monitoring an analyte state of a host; presenting, at the remote monitor, the notification message to activate the remote monitor, wherein the remote monitor is configured by the server to receive the notification message to augment the receiver monitoring of the analyte state of the host; accessing, by the remote monitor, the server, in response to the presenting of the notification message; and receiving, in response to the accessing, information including at least the analyte sensor data. Related systems, methods, and articles of manufacture are also disclosed.

Abstract: An apparatus includes a first substrate, a second substrate, and an intermediate layer disposed between the first and second substrates. The intermediate layer is configured to be a first point of failure or breakage of the apparatus under an applied force. The apparatus can further include a bonding layer disposed between the first and second substrates. The bonding layer is configured to bond the intermediate layer to the first and second substrates. The apparatus can further include a fastener coupled to the first and second substrates. The fastener is configured to secure the intermediate layer to the first and second substrates. The intermediate layer can include a coating applied to the first substrate or the second substrate. The apparatus can further include a second intermediate layer disposed between the first substrate and the fastener or the second substrate and the fastener.

Abstract: The present disclosure relates to a laboratory execution system that provides for automation of laboratory processes. A centralized data management system may be dynamically updated and used to facilitate management of components of the laboratory execution system, such as an automation system and an analytics results management system that may facilitate complex analytical functions, such as synthesizing raw test data. Potential workflows include the detection of specific molecules of interest.

Abstract: A valve repair system for repairing a native valve of a patient during a non-open-heart procedure includes a delivery device and a valve repair device. The valve repair device include a pair of paddles, first gripping member, a second gripping member, and a spacer. First and second gripping member controls or first and second gripping member control portions are coupled to the first and second gripping members to move the gripping members. The spacer element is configured to close a gap in the native valve of the patient when the valve repair device is attached to the native valve.

Abstract: A valve repair device for repairing a native valve of a patient. The valve repair device includes a compressible spacer element, a pair of paddles, and a pair of gripping members. The pair of paddles are coupled to the spacer element. The pair of gripping members are disposed between the pair of paddles. The paddles and the gripping members are configured to attach to leaflets of a heart valve.

Abstract: Described herein, are battery separators, comprising the following: a microporous polymeric film; and an optional coating layer on at least one side of the microporous polymeric film, wherein at least one of the microporous polymeric film and the optional coating comprises an additive. The additive is selected from the group consisting of a lubricating agent, a plasticizing agent, a nucleating agent, a shrinkage reducing agent, a surfactant, an SEI improving agent, a cathode protection agent, a flame retardant additive, LiPF6 salt stabilizer, an overcharge protector, an aluminum corrosion inhibitor, a lithium deposition agent or improver, or a solvation enhancer, an aluminum corrosion inhibitor, a wetting agent, and a viscosity improver. Also, described herein are batteries, including lithium-ion batteries, comprising one or more of the described separators. Methods for making the battery separators are also described.

Abstract: A system for communicating slippage experienced by at least one traction device of a work machine, to a remote operator interface for controlling the work machine through the remote operator interface is described. The system includes a controller configured to receive data associated with a speed of the at least one traction device of the work machine and determine a slippage condition of the at least one traction device based on the data. The controller is further configured to activate a visual overlay over a virtual image, of the at least one traction device, displayed in a video feed to represent the slippage condition on the remote operator interface. The video feed is a real-time video feed, indicating one or more operations of the work machine, displayed on the remote operator interface.

Abstract: The present disclosure relates to aerosol delivery devices, methods of forming such devices, and elements of such devices. In some embodiments, the present disclosure provides a heating member that can be formed of a heating element conformed to a heater substrate configured as a truncated cone (or similar shape) having a first end of a first size and a second end of greater size. In some embodiments, the disclosure provides methods of forming an aerosol delivery device, which can include providing a shell, providing a heating member formed of a heating element conformed to a substrate, configuring the heating member as a truncated cone (or similar shape) having a first end of a first size and a second end of greater size, and inserting the heating member within the shell.

Abstract: The present invention relates to new pyrrolopyridine compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibition of JAK1 and JAK3 kinase activity in a human or animal subject are also provided for the treatment diseases such as pruritus, alopecia, androgenetic alopecia, alopecia areata, vitiligo and psoriasis.

Abstract: Components for valve treatment systems are disclosed. Valve treatment systems can include a delivery system for an implantable device. The delivery system can include one or more of clasp control components slidably disposed on a catheter handle, a control element for opening and closing the implantable device, a catheter assembly with features to reduce friction with another catheter assembly, grips for attaching catheter assemblies to clamps, catheter assemblies with features that stiffen or provide variable stiffness, and catheter assemblies with one or more steering control lumens incorporated into a reinforcement layer.

Abstract: An aqueous treating medium may include water; an acid selected from the group consisting of: HCl, HBr, HNO3, H2SO4, H2SO3, H3PO4, H3PO2, HOAc, citric acid, tartaric acid, ascorbic acid, EDTA, methanesulfonic acid, toluenesulfonic acid, and combinations thereof, wherein a concentration of the acid in the aqueous treating medium is from 0.5 M to 1.5 M; a salt, wherein a concentration of the salt in the aqueous treating medium is from greater than 0 M to 2 M; a fluoride-containing compound selected from the group consisting of: HF, NaF, NH4HF2, and combinations thereof, wherein a concentration of the fluoride-containing compound in the aqueous treating medium is from 0.026 M to 0.26 M; and silica, wherein the aqueous treating medium is saturated with silica.