Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The implantable prosthetic device can be used to repair a native valve, such as a native mitral valve.

Abstract: An implantable device includes an adjustable spacer and at least one anchor. The adjustable spacer is configured to be positioned between native heart valve leaflets to reduce regurgitation therebetween. An clastic or stretchable cover is part of or disposed over the adjustable spacer.

Abstract: An implantable prosthetic device has a coaptation element. At least a portion of the coaption element is formed from the strip of material. A pair of paddles are connected to the coaption element. The paddles are movable between an open position and a closed position. The paddles are configured to attach to the native valve of the patient.

Abstract: A new composition of matter has the molecular structure [I]: Formula (I) wherein R1 is an alkyl, cycloalkyl, aralkyl group having ?1 to ?10 carbon atoms; R2 is selected from the group consisting of an aliphatic C1-C10 group, an unsaturated C1-C10 chain, C4-C9 group with a cyclic portion and C4-C10 group with an aromatic portion, and combinations thereof; R3 is selected from the group consisting of hydrogen, an aliphatic C1-C10 group, an unsaturated C2-C10 chain, a C4-C10 group with a cyclic portion, C4-C10 group with an aromatic portion, and combinations thereof; and R4 is a terminal functional group selected from the group consisting of amide [—CONH2], acid [—COOH], amine [—CH2—NH2], guanamine [—(C3N3)—(NH2)2], organic heterocyclic [—CHN4], and combinations thereof; and wherein said composition of matter of the molecular structure [I] excludes 2-[(3-amino-1-ethylpropyl)amino]ethanol.

Abstract: In accordance with at least selected embodiments, a battery separator or separator membrane comprises one or more co-extruded multi-microlayer membranes optionally laminated or adhered to another polymer membrane. The separators described herein may provide improved strength, for example, improved puncture strength, particularly at a certain thickness, and may exhibit improved shutdown and/or a reduced propensity to split.

Abstract: A bicycle includes a front wheel and a rear wheel and a frameset supported on the front wheel and the rear wheel. The frameset includes a main frame and a front fork rotationally coupled to the main frame. The main frame includes a top tube, a head tube rotationally supporting the front fork, a down tube coupling the head tube to a bottom bracket, a seat tube extending downward from the top tube and including a lower end spaced from the bottom bracket, a seatstay extending rearward from the lower end of the seat tube, and a strut member extending forward from the lower end of the seat tube and connecting the seat tube to the down tube.

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The clasps include a fixed arm and a plurality of movable arms. The implantable prosthetic device can be used to repair a native valve, such as a native mitral valve.

Abstract: A prosthetic heart valve configured to be expanded within a native valve annulus, engage surrounding tissue, and constricted tissue inward to enhance contact between the tissue and the valve. The heart valve may have a structural valve stent with an outer constricting structure having tissue-engaging members or anchors. The constricting structure may be intrinsic or extrinsic. One intrinsic version includes a plurality of arms that are arranged to constrict inward toward a central valve portion, or a fabric structure with tissue anchors and surrounding an inner valve member may be cinched to pull the tissue inward. The anchors may engage tissue around the annulus in the atrium, or surround leaflets in the ventricle, or grasp leaflets from within.

Abstract: A system is provided that comprises an inlet fluid conduit, an outer frame, and an inner frame coupled to the outer frame via at least one mass measurement device, where the inner frame includes an opening. A bi-directional scale is pivotally connected to the inner frame along an axis of rotation, where the bi-directional scale comprises filter media positioned between a first material receiving receptable and a second material receiving receptable. The first material receiving receptacle is configured to receive a fluid mixture from the inlet fluid conduit. The system comprises a separator pivoting system coupled to the bi-directional scale. The separator pivoting system is configured to: rotate the bi-directional scale about the axis of rotation, wherein following rotation of the bi-directional scale, the second material receiving receptacle is positioned to receive the fluid mixture from the inlet fluid conduit.

Abstract: Apparatuses, systems, and methods for prosthetic valves. The prosthetic valves disclosed herein may be utilized for improved deployment, sealing, and anchoring to an implantation site. An implantation site may comprise a native heart valve or another implantation site in examples. Examples of prosthetic valves may include a proximal tensioning body positioned at a proximal portion of the prosthetic valve and a distal tensioning body positioned at a distal portion of the prosthetic valve. A sealing skirt may have a proximal end portion coupled to the proximal tensioning body and a distal end portion coupled to the distal tensioning body. The sealing skirt may be tensioned by the proximal tensioning body and the distal tensioning body and deflectable to conform to a shape of the native valve.

Abstract: A locking case comprising a base and a lid, where the base and/or the lid comprises a double wall design including a first wall, a second wall, and a channel formed between the first and the second wall; a gasket positioned within the channel; at least one pressure equalization element integrated into the case; a latch comprising a first end and a second end, and a first one or more protrusions positioned between the first end and the second end, the second end comprising a second protrusion configured for removably engaging with a third protrusion of the base, where the first end is rotatably coupled to the lid; and where, closure of the latch is configured to cause the first one or more protrusions of the latch to interface with one or more of the base and the lid to compress the gasket between the base and the lid.

Abstract: A locking case including a base and a lid includes a latch recess integrated into an outer profile of the case, and a latch installed within the latch recess. The latch includes a latch handle including a first end, rotatably coupled with the lid, and a second end including an end protrusion configured for removably engaging with a first portion of the base. The latch also includes a passthrough feature for accommodating a lock mechanism therethrough. The latch handle is larger than the locking mechanism. The latch recess fully accommodates the latch and most or all of the lock mechanism therein when the second end of the latch handle is engaged with the first portion of the base and the lock mechanism is installed through the passthrough feature such that the latch and the lock mechanism do not substantially protrude from the outer profile of the case.

Abstract: An organizer system for use with a case including a base and a lid configured to be matingly coupled together for containing an object therein is disclosed. The organizer system includes a panel system including at least one panel, the at least one panel including a plurality of cutouts formed therein, and a plurality of mounting blocks, each one of the plurality of mounting blocks including a block body and at least one stud. The stud is configured to be removably insertable into one of the plurality of cutouts. When the mounting blocks are inserted into the cutouts adjacent to the object then the base and the lid are coupled together, the panel system and the mounting blocks cooperate to prevent shifting of the object within the case. A method for storing an object in a case using an organizer system is also disclosed.

Abstract: A sensor bearing unit comprising: a bearing comprising first and second rings, each provided with an outer cylindrical surface, an inner cylindrical surface, and lateral surfaces, and an impulse ring provided with a target holder being axially mounted against one of said lateral surfaces, and comprising a fixing portion secured to the first ring and coming into radial contact with said one of cylindrical surfaces and an abutment portion coming into axial contact with said lateral surface. Besides, at least one of the lateral and cylindrical surfaces is provided with a textured area comprising a plurality of ribs, and the abutment portion and/or the fixing portion of the target holder is made of a hard material and comprise a soft coating covering the hard material and inside which the ribs are engaged.

Abstract: An implantable device includes an adjustable spacer and at least one anchor. The adjustable spacer is configured to be positioned between native heart valve leaflets to reduce regurgitation therebetween. The adjustable spacer can comprise a first side and a second side opposite the first side. Each side can be adjustable between a first width and a second width. Each side can be independently moved between the first width and the second width. The adjustable spacer can be made from a sponge material.

Abstract: This disclosure describes systems, methods, and apparatus for a locking folding knife having a handle lock and a safety switch arranged around and rotatable around a pivot axis of the knife. In an engaged position the switch overlaps at least a portion of the handle lock and prevents it from moving into an unlocked position. A spring, such as a wire form spring, can be arranged within a pocket of the switch, and when the switch is moved between engaged and disengaged positions the spring can be compressed generating a rotational bias on the switch urging the switch toward either the engaged or disengaged position.

Abstract: A valve repair device for repairing a native valve of a patient can include a coaptationm element. The valve repair device can include a pair of paddles. The coaption element can comprise a fabric. The pair of paddles can be connected to the coaption element. The paddles are movable between an open position and a closed position. The paddles are configured to attach to the native valve of the patient.

Abstract: An implantable prosthetic device includes a coaption portion, paddles, and clasps. The paddles are moveable from a closed position to an open position. The clasps are also moveable from an open position to a closed position. The implantable prosthetic device can be used to repair a native valve, such as a native mitral valve. Other embodiments are also described.