Patents by Inventor Eric Roche

Eric Roche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
    Patent number: 11957698
    Abstract: Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising a synergistic combination of thermolysin and at least one aminoglycoside antibacterial agent.
    Type: Grant
    Filed: July 8, 2022
    Date of Patent: April 16, 2024
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Aleksa Jovanovic, Lei Shi, Eric Roche, Paul Renick
  • USE OF THERMOLYSIN TO REDUCE OR ELIMINATE BACTERIAL BIOFILMS FROM SURFACES
    Publication number: 20230346898
    Abstract: Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising thermolysin.
    Type: Application
    Filed: March 13, 2023
    Publication date: November 2, 2023
    Inventors: Lei SHI, Catherine VAN DER KAR, Aleksa JOVANOVIC, Eric ROCHE
  • SYNERGISTIC ANTIBACTERIAL ACTIVITY OF MEDIUM POLARITY OILS IN COMBINATION WITH ANTIBACTERIAL AGENTS ON BACTERIAL BIOFILMS
    Publication number: 20230345938
    Abstract: The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.
    Type: Application
    Filed: April 3, 2023
    Publication date: November 2, 2023
    Inventors: Aleksa JOVANOVIC, Lei SHI, Eric ROCHE, Paul RENICK
  • SYNERGISTIC COMBINATION OF THERMOLYSIN AND AN ANTIBACTERIAL AGENT TO REDUCE OR ELIMINATE BACTERIAL BIOFILMS FROM SURFACES
    Publication number: 20230201229
    Abstract: Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising a synergistic combination of thermolysin and at least one aminoglycoside antibacterial agent.
    Type: Application
    Filed: July 8, 2022
    Publication date: June 29, 2023
    Inventors: Aleksa JOVANOVIC, Lei SHI, Eric ROCHE, Paul RENICK
  • Synergistic antibacterial activity of medium polarity oils in combination with antibacterial agents on bacterial biofilms
    Patent number: 11641856
    Abstract: The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: May 9, 2023
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Aleksa Jovanovic, Lei Shi, Eric Roche, Paul Renick
  • Use of thermolysin to reduce or eliminate bacterial biofilms from surfaces
    Patent number: 11628207
    Abstract: Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising thermolysin.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: April 18, 2023
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Lei Shi, Catherine Van Der Kar, Aleksa Jovanovic, Eric Roche
  • Synergistic combination of thermolysin and an antibacterial agent to reduce or eliminate bacterial biofilms from surfaces
    Patent number: 11413300
    Abstract: Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising a synergistic combination of thermolysin and at least one aminoglycoside antibacterial agent.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: August 16, 2022
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Aleksa Jovanovic, Lei Shi, Eric Roche, Paul Renick
  • SYNERGISTIC ANTIBACTERIAL ACTIVITY OF MEDIUM POLARITY OILS IN COMBINATION WITH ANTIBACTERIAL AGENTS ON BACTERIAL BIOFILMS
    Publication number: 20220192191
    Abstract: The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.
    Type: Application
    Filed: December 8, 2021
    Publication date: June 23, 2022
    Applicant: SMITH & NEPHEW, INC.
    Inventors: Aleksa JOVANOVIC, Lei SHI, Eric ROCHE, Paul RENICK
  • Synergistic antibacterial activity of medium polarity oils in combination with antibacterial agents on bacterial biofilms
    Patent number: 11197476
    Abstract: The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: December 14, 2021
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Aleksa Jovanovic, Lei Shi, Eric Roche, Paul Renick
  • Use of seaprose to remove bacterial biofilm
    Patent number: 11096992
    Abstract: A method of disrupting a bacterial biofilm present on a surface, comprising applying a composition that includes a semi-alkaline protease produced by the fermentation of the fungus Aspergillus melleus (Seaprose) to the bacterial biofilm, wherein application of the composition to the bacterial biofilm disrupts the matrix of the bacterial biofilm.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: August 24, 2021
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Lei Shi, Aleksa Jovanovic, Catherine Van Der Kar, Eric Roche
  • Polyamide beads and method for the production thereof
    Patent number: 10940612
    Abstract: Certain polyamide beads or granules are useful as a sustaining material for underground natural or artificial cracks of the earth's crust essentially employed for the extraction of hydrocarbons such as crude oil or natural gas; such polyamide beads have a spherical or ellipsoidal shape and have a surface free of concave portions, advantageously having a uniform shape, and having a mean diameter lower than or equal to 1.7 mm and a porosity lower than 0.1 ml/g, and are produced using a particular cutting device/extruder.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: March 9, 2021
    Assignees: Performance Polyamides S.A.S., Gala Industries. Inc.
    Inventors: Jean-Francois Estur, Eric Roche, Michael Eloo, Berthold Druschel
  • SYNERGISTIC ANTIBACTERIAL ACTIVITY OF MEDIUM POLARITY OILS IN COMBINATION WITH ANTIBACTERIAL AGENTS ON BACTERIAL BIOFILMS
    Publication number: 20200085044
    Abstract: The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.
    Type: Application
    Filed: August 1, 2019
    Publication date: March 19, 2020
    Applicant: SMITH & NEPHEW, INC.
    Inventors: Aleksa JOVANOVIC, Lei SHI, Eric ROCHE, Paul RENICK
  • SYNERGISTIC COMBINATION OF THERMOLYSIN AND AN ANTIBACTERIAL AGENT TO REDUCE OR ELIMINATE BACTERIAL BIOFILMS FROM SURFACES
    Publication number: 20190365791
    Abstract: Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising a synergistic combination of thermolysin and at least one aminoglycoside antibacterial agent.
    Type: Application
    Filed: January 26, 2018
    Publication date: December 5, 2019
    Applicant: SMITH & NEPHEW, INC.
    Inventors: Aleksa JOVANOVIC, Lei SHI, Eric ROCHE, Paul RENICK
  • USE OF THERMOLYSIN TO REDUCE OR ELIMINATE BACTERIAL BIOFILMS FROM SURFACES
    Publication number: 20190262437
    Abstract: Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising thermolysin.
    Type: Application
    Filed: July 26, 2017
    Publication date: August 29, 2019
    Applicant: SMITH & NEPHEW, INC.
    Inventors: Lei SHI, Catherine VAN DER KAR, Aleksa JOVANOVIC, Eric ROCHE
  • POLYAMIDE BEADS AND METHOD FOR THE PRODUCTION THEREOF
    Publication number: 20190152096
    Abstract: Certain polyamide beads or granules are useful as a sustaining material for underground natural or artificial cracks of the earth's crust essentially employed for the extraction of hydrocarbons such as crude oil or natural gas; such polyamide beads have a spherical or ellipsoidal shape and have a surface free of concave portions, advantageously having a uniform shape, and having a mean diameter lower than or equal to 1.7 mm and a porosity lower than 0.1 ml/g, and are produced using a particular cutting device/extruder.
    Type: Application
    Filed: January 30, 2019
    Publication date: May 23, 2019
    Inventors: JEAN-FRANCOIS ESTUR, ERIC ROCHE, MICHAEL ELOO, BERTHOLD DRUSCHEL
  • SYNERGISTIC ANTIBACTERIAL ACTIVITY OF MEDIUM POLARITY OILS IN COMBINATION WITH ANTIBACTERIAL AGENTS ON BACTERIAL BIOFILMS
    Publication number: 20180289003
    Abstract: The compositions of the present invention comprise at least one medium polarity oil and at least one antibacterial agent, the combination of which produces a synergistic antibacterial effect against bacterial biofilms. Methods are disclosed for the reduction of bacteria in and/or elimination of bacterial biofilms on biological and non-biological surfaces, as well as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms.
    Type: Application
    Filed: August 23, 2016
    Publication date: October 11, 2018
    Applicant: SMITH & NEPHEW, INC.
    Inventors: Aleksa JOVANOVIC, Lei SHI, Eric ROCHE, Paul RENICK
  • POLYAMIDE BEADS AND METHOD FOR THE PRODUCTION THEREOF
    Publication number: 20170239844
    Abstract: Certain polyamide beads or granules are useful as a sustaining material for underground natural or artificial cracks of the earth's crust essentially employed for the extraction of hydrocarbons such as crude oil or natural gas; such polyamide beads have a spherical or ellipsoidal shape and have a surface free of concave portions, advantageously having a uniform shape, and having a mean diameter lower than or equal to 1.7 mm and a porosity lower than 0.1 ml/g, and are produced using a particular cutting device/extruder.
    Type: Application
    Filed: May 8, 2017
    Publication date: August 24, 2017
    Inventors: JEAN-FRANCOIS ESTUR, ERIC ROCHE, MICHAEL ELOO, BERTHOLD DRUSCHEL
  • Polyamide beads and method for the production thereof
    Patent number: 9676121
    Abstract: Certain polyamide beads or granules are useful as a sustaining material for underground natural or artificial cracks of the earth's crust essentially employed for the extraction of hydrocarbons such as crude oil or natural gas; such polyamide beads have a spherical or ellipsoidal shape and have a surface free of concave portions, advantageously having a uniform shape, and having a mean diameter lower than or equal to 1.7 mm and a porosity lower than 0.1 ml/g, and are produced using a particular cutting device/extruder.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: June 13, 2017
    Assignees: RHODIA OPERATIONS, GALA INDUSTRIES, INC.
    Inventors: Jean-Francois Estur, Eric Roche, Michael Eloo, Berthold Druschel
  • POLYAMIDE BEADS AND METHOD FOR THE PRODUCTION THEREOF
    Publication number: 20150151452
    Abstract: Certain polyamide beads or granules are useful as a sustaining material for underground natural or artificial cracks of the earth's crust essentially employed for the extraction of hydrocarbons such as crude oil or natural gas; such polyamide beads have a spherical or ellipsoidal shape and have a surface free of concave portions, advantageously having a uniform shape, and having a mean diameter lower than or equal to 1.7 mm and a porosity lower than 0.1 ml/g, and are produced using a particular cutting device/extruder.
    Type: Application
    Filed: December 1, 2014
    Publication date: June 4, 2015
    Inventors: Jean-Francois ESTUR, Eric Roche, Michael Eloo, Berthold Druschel
  • USE OF SEAPROSE TO REMOVE BACTERIAL BIOFILM
    Publication number: 20150118219
    Abstract: Disclosed are compositions and methods for their use in disrupting a bacterial biofilm present on a surface, comprising applying a composition that includes Seaprose to the bacterial biofilm, wherein application of the composition to the bacterial biofilm disrupts the matrix of the bacterial biofilm.
    Type: Application
    Filed: May 10, 2013
    Publication date: April 30, 2015
    Inventors: Lei Shi, Aleksa Jovanovic, Catherine Van Der Kar, Eric Roche