Patents by Inventor Eric Ryba

Eric Ryba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190365453
    Abstract: A differential pressure limiter (226) for limiting a differential fluid pressure of cryogenic fluid (228) during a cryoablation procedure includes one or more of a fluid source (216), a pressure regulator (230), one or more proportional valves (232) and a backpressure regulator (234). The fluid source (216) selectively retains cryogenic fluid (228). The pressure regulator (230) receives cryogenic fluid (228) from the fluid source (216) and regulates a fluid pressure of the cryogenic fluid (228). The proportional valve(s) (232) receives cryogenic fluid (228) from the pressure regulator (230) and at least partially controls a flow rate of the cryogenic fluid (228).
    Type: Application
    Filed: August 14, 2019
    Publication date: December 5, 2019
    Inventors: Chadi Harmouche, Eric Ryba
  • Publication number: 20190183556
    Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
    Type: Application
    Filed: December 14, 2018
    Publication date: June 20, 2019
    Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Mark Gelfand, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Mark S. Leung, Gwenda McMullin, Barry Mullins, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vicenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Michael Turovskiy
  • Patent number: 10188445
    Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: January 29, 2019
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Mark Gelfand, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Mark S. Leung, Gwenda Francis, Barry Mullins, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Michael Turovskiy
  • Patent number: 10004550
    Abstract: Catheter apparatuses, systems, and methods for cryogenically modulating neural structures of the renal plexus by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a cryo-applicator to a renal artery via an intravascular path. Cryogenic renal neuromodulation may be achieved via application of cryogenic temperatures to modulate neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: June 26, 2018
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Eric Ryba, Naomi Buckley, Benjamin J. Clark, Danny Donovan, Luke Hughes, Brian Kelly, Gwenda McMullin, Karun D. Naga, Stephen Nash, Roman Turovskiy, Lana Wooley, Denise Zarins, Mark Gelfand, Mark S. Leung
  • Publication number: 20180116704
    Abstract: Methods and cryogenic devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation. Some methods include advancing a cryo-ablation catheter into a patient's vasculature and ablating tissue within a carotid septum.
    Type: Application
    Filed: November 7, 2017
    Publication date: May 3, 2018
    Inventors: Eric RYBA, Mark GELFAND
  • Patent number: 9808303
    Abstract: Methods and cryogenic devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation. Some methods include advancing a cryo-ablation catheter into a patient's vasculature and ablating tissue within a carotid septum.
    Type: Grant
    Filed: August 2, 2016
    Date of Patent: November 7, 2017
    Assignee: Cibiem, Inc.
    Inventors: Eric Ryba, Mark Gelfand
  • Publication number: 20170056087
    Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
    Type: Application
    Filed: August 5, 2016
    Publication date: March 2, 2017
    Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Mark Gelfand, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Mark S. Leung, Gwenda McMullin, Barry Mullins, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vicenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Michael Turovskiy
  • Publication number: 20160338753
    Abstract: Methods and cryogenic devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation. Some methods include advancing a cryo-ablation catheter into a patient's vasculature and ablating tissue within a carotid septum.
    Type: Application
    Filed: August 2, 2016
    Publication date: November 24, 2016
    Inventors: Eric RYBA, Mark GELFAND
  • Patent number: 9439708
    Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
    Type: Grant
    Filed: October 23, 2011
    Date of Patent: September 13, 2016
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Gwenda McMullin, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Mark Gelfand, Mark S. Leung, Barry Mullins, Michael Turovskiy
  • Publication number: 20160058488
    Abstract: A cryogenic device having a filter device fluidly connected between a valve and a cooling fluid cartridge. The filter device filters solid and fluid impurities received from the cartridge. The filter device also captures fluid impurities from the cryogenic device when not in use.
    Type: Application
    Filed: November 18, 2015
    Publication date: March 3, 2016
    Inventors: Michael Fourkas, Eric Ryba, Jesse Rosen, Punit Govenji
  • Publication number: 20160038212
    Abstract: Catheter apparatuses, systems, and methods for cryogenically modulating neural structures of the renal plexus by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a cryo-applicator to a renal artery via an intravascular path. Cryogenic renal neuromodulation may be achieved via application of cryogenic temperatures to modulate neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.
    Type: Application
    Filed: July 15, 2015
    Publication date: February 11, 2016
    Applicant: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Eric Ryba, Naomi Buckley, Benjamin J. Clark, Danny Donovan, Luke Hughes, Brian Kelly, Gwenda McMullin, Karun D. Naga, Stephen Nash, Roman Turovskiy, Lana Wooley, Denise Zarins, Mark Gelfand, Mark S. Leung
  • Patent number: 9155584
    Abstract: A cryogenic device having a filter device fluidly connected between a valve and a cooling fluid cartridge. The filter device filters solid and fluid impurities received from the cartridge. The filter device also captures fluid impurities from the cryogenic device when not in use.
    Type: Grant
    Filed: January 14, 2013
    Date of Patent: October 13, 2015
    Assignee: MyoScience, Inc.
    Inventors: Michael Fourkas, Eric Ryba, Jesse Rosen, Punit Govenji
  • Patent number: 9060754
    Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment includes an elongated shaft and a cooling assembly at a distal portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site within or otherwise proximate a renal artery. The cryotherapeutic device can further include a supply lumen configured to carry liquid refrigerant toward the cooling assembly. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when in a deployed state.
    Type: Grant
    Filed: October 23, 2011
    Date of Patent: June 23, 2015
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Seamus Ledwith, Gwenda McMullin, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Mark Gelfand, Mark S. Leung, Barry Mullins
  • Patent number: 9017317
    Abstract: Cryotherapeutic systems configured for refrigerant recompression and associated devices, systems, and methods are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment includes a high-pressure line, a low-pressure line, a recompression unit, and a cryo-catheter. The recompression unit increases the pressure of refrigerant from the low-pressure line to the high-pressure line to a treatment pressure sufficient for cryogenic alteration of tissue. The high-pressure line and the low-pressure line include, respectively, a first connector and a second connector. The cryo-catheter includes a shaft, a supply lumen in the shaft that is coupled to the first connector, an exhaust lumen in the shaft that is coupled to the second connector, and a cryo-applicator attached to the shaft having a cooling chamber configured to receive refrigerant from the supply lumen and to return refrigerant via the exhaust lumen to the low-pressure line.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: April 28, 2015
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Eric Ryba, Gary Kelly
  • Patent number: 8945107
    Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
    Type: Grant
    Filed: October 23, 2011
    Date of Patent: February 3, 2015
    Assignee: Medtronic Ardian Luxembourg S.a.r.l.
    Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Seamus Ledwith, Gwenda McMullin, Karun D. Naga, Stephen Nash, Francesco Piccagli, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Mark Gelfand, Mark S. Leung, Barry Mullins
  • Publication number: 20140249610
    Abstract: Refrigerant cartridges for cryotherapeutic neuromodulation and associated systems and methods are disclosed herein. In one embodiment, for example, a cryotherapeutic system includes a shaft having a proximal portion, a distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site. The supply lumen can be configured to receive a refrigerant from a refrigerant cartridge. The refrigerant in the refrigerant cartridge can have a moisture concentration of at most 10 ppm. The system can further include a cooling assembly at the distal portion of the shaft that has an expansion chamber in fluid communication with the supply lumen.
    Type: Application
    Filed: October 5, 2012
    Publication date: September 4, 2014
    Inventor: Eric Ryba
  • Publication number: 20140163538
    Abstract: Cryotherapeutic systems configured for refrigerant recompression and associated devices, systems, and methods are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment includes a high-pressure line, a low-pressure line, a recompression unit, and a cryo-catheter. The recompression unit increases the pressure of refrigerant from the low-pressure line to the high-pressure line to a treatment pressure sufficient for cryogenic alteration of tissue. The high-pressure line and the low-pressure line include, respectively, a first connector and a second connector. The cryo-catheter includes a shaft, a supply lumen in the shaft that is coupled to the first connector, an exhaust lumen in the shaft that is coupled to the second connector, and a cryo-applicator attached to the shaft having a cooling chamber configured to receive refrigerant from the supply lumen and to return refrigerant via the exhaust lumen to the low-pressure line.
    Type: Application
    Filed: December 6, 2012
    Publication date: June 12, 2014
    Inventors: Eric Ryba, Gary Kelly
  • Publication number: 20130324987
    Abstract: Methods and cryogenic devices for assessing, and treating patients having sympathetically mediated disease, involving augmented peripheral chemoreflex and heightened sympathetic tone by reducing chemosensor input to the nervous system via carotid body ablation.
    Type: Application
    Filed: June 3, 2013
    Publication date: December 5, 2013
    Inventors: Mark Leung, Eric Ryba, Charles Lennox, Ary Chernomorsky, Zoar Jacob Engelman, Marat Fudim, Martin M. Grasse, Mark Gelfand, Howard Levin, Brett Schleicher
  • Publication number: 20120143294
    Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
    Type: Application
    Filed: October 23, 2011
    Publication date: June 7, 2012
    Applicant: Medtronic Adrian Luxembourg S.a.r.l.
    Inventors: Benjamin J. Clark, Tim Huynh, Micheal Moriarty, Eric Ryba, Roman Turovskiy
  • Publication number: 20120136418
    Abstract: Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.
    Type: Application
    Filed: October 23, 2011
    Publication date: May 31, 2012
    Applicant: Medtronic Ardian Luxembourg S.a.r.l
    Inventors: Naomi Buckley, Benjamin J. Clark, Michael Cummins, Danny Donovan, Luke Hughes, Brian Kelly, Gary Kelly, Grace Kelly, John Kelly, Seamus Ledwith, Gwenda McMullin, Karun D. Naga, Stephen Nash, Eric Ryba, Fiachra Sweeney, Vincenzo Tilotta, Roman Turovskiy, Lana Woolley, Denise Zarins, Mark Gelfand, Mark S. Leung, Barry Mullins