Abstract: The present disclosure provides methods for preparing MCL1 inhibitors or a salt thereof and related key intermediates.

Abstract: A technique to eliminate perceptible flickering by LEDs being dimmed by PWM pulses is disclosed. A controllable oscillator controls a switching frequency of a converter for supplying a regulated current or regulated voltage. The converter controls a first switch at a switching frequency. A varying second signal level is generated by a spread spectrum control (SSC) circuit for controlling the oscillator to vary the switching frequency during operation. A PWM dimming circuit generates a string of PWM pulses that control a switch in series with the LEDs. The SSC circuit is synchronized with the PWM pulses to generate the same second signal level at a start of each PWM pulse, such that the switching frequency of the converter is forced to be substantially the same at the start of each PWM pulse while the pulse widths are constant. The repeating driving current waveform eliminates perceptible flicker by the LEDs.

Abstract: A technique to eliminate perceptible flickering by LEDs being dimmed by PWM pulses is disclosed. A controllable oscillator controls a switching frequency of a converter for supplying a regulated current or regulated voltage. The converter controls a first switch at a switching frequency. A varying second signal level is generated by a spread spectrum control (SSC) circuit for controlling the oscillator to vary the switching frequency during operation. A PWM dimming circuit generates a string of PWM pulses that control a switch in series with the LEDs. The SSC circuit is synchronized with the PWM pulses to generate the same second signal level at a start of each PWM pulse, such that the switching frequency of the converter is forced to be substantially the same at the start of each PWM pulse while the pulse widths are constant. The repeating driving current waveform eliminates perceptible flicker by the LEDs.

Abstract: A circuit for controlling pulsed current to a load, one application of which is in LED dimmer circuitry, comprises first and second reference nodes for receiving a supply voltage, an input node for receiving a timing signal such as a PWM signal, and a controlled switch coupled between the first and second reference voltage nodes for supplying current to the load. Pull-up circuitry may be coupled between a control electrode of the controlled switch and first reference voltage node, and a pull-down switch coupled between the control electrode and second reference voltage node. A control circuit coupled between the input node and control electrode of the controlled switch is configured to control the controlled switch in response to the timing signal. The circuit may further include a reference voltage source configured for producing a voltage of magnitude independent of supply voltage magnitude.

Abstract: A dither unit preferably comprises an offset generator, an adjusted coordinate generator and a dither matrix. The offset generator is coupled to receive information about the relative position of the sub-sample being dithered, and in response generates offset values. The output of the offset generator along with the pixel coordinates are provided to the adjusted coordinate generator which generates adjusted coordinate values used by the dither matrix. The adjusted coordinate values along with a color value are received by the dither matrix, which in response, generates a dithered value for the sub-sample that can be stored back in the over sampling buffer for additional computation.

Abstract: The present invention provides an alpha blending unit that is able to perform alpha blending on sub-samples of a pixel in an efficient manner. The alpha blending unit preferably comprises a plurality of registers for storing a source color, a blending value, and a plurality of destination sub-sample values, multipliers, adders, an accumulator and a divider. The alpha blending unit advantageously sums the destination sub-sample values and then divides them by the number of sub-samples to generate a combined destination color value. This combined destination color value along with the source color and a blending value are then provided to the multipliers, and adders to generate a new destination color value for the pixel.