Patents by Inventor Eric Sasso

Eric Sasso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR CARDIOVASCULAR DISEASE IN RHEUMATOID ARTHRITIS
    Publication number: 20240077499
    Abstract: This invention includes methods for assessing and treating risk of cardiovascular disease (CVD) in a subject with an inflammatory disease, for example rheumatoid arthritis (RA). Provided are methods for assessing risk, for recommending therapy, for prognosis and monitoring, and for treatment, which are advantageously accurate for CVD in RA. The methods include measuring quantitative data for biomarkers, calculating a CVD risk score for a subject using training data, and validating the CVD risk score with a set of validation clinical data.
    Type: Application
    Filed: September 10, 2021
    Publication date: March 7, 2024
    Inventors: JEFFREY R. CURTIS, ALEXANDER GUTIN, JERRY LANCHBURY, ERIC SASSO, DARL FLAKE, ELENA HITRAYA, CHERYL CHIN
  • Biomarkers and methods for assessing psoriatic arthritis disease activity
    Patent number: 11656227
    Abstract: Provided herein are biomarkers and methods for generating scores useful for assessing psoriatic arthritis (PsA) disease activity in subjects previously diagnosed with PsA. The invention also provides predictive model methods based on the biomarkers, as well as computer systems, software embodiments of the models for scoring and optionally classifying samples, and methods of recommending optimal therapeutic regimens.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: May 23, 2023
    Inventors: Eric Sasso, Paul Scott Eastman, Rebecca Bolce, Arthur Kavanaugh
  • METHODS OF PREDICTING DISEASE PROGRESSION IN RHEUMATOID ARTHRITIS
    Publication number: 20230142317
    Abstract: Methods for evaluating the risk of radiographic progression in a subject with RA are provided. Also provided are methods of determining treatment efficacy for a subject with RA. Methods of selecting a treatment regimen for a subject with RA are also provided.
    Type: Application
    Filed: April 8, 2021
    Publication date: May 11, 2023
    Inventors: Darl Flake, Eric Sasso
  • Biomarkers and methods for measuring and monitoring axial spondyloarthritis activity
    Patent number: 11493512
    Abstract: Biomarkers useful for diagnosing and assessing inflammatory disease activity, for prediction of risk for progressive spinal and joint damage, in particular for axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), and for generating a dataset are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: November 8, 2022
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Paul Scott Eastman, Eric Sasso
  • BIOMARKERS AND METHODS FOR ASSESSING PSORIATIC ARTHRITIS DISEASE ACTIVITY
    Publication number: 20220214341
    Abstract: Provided herein are biomarkers and methods for generating scores useful for assessing psoriatic arthritis (PsA) disease activity in subjects previously diagnosed with PsA. The invention also provides predictive model methods based on the biomarkers, as well as computer systems, software embodiments of the models for scoring and optionally classifying samples, and methods of recommending optimal therapeutic regimens.
    Type: Application
    Filed: September 9, 2021
    Publication date: July 7, 2022
    Inventors: Eric Sasso, Paul Scott Eastman, Rebecca Bolce, Arthur Kavanaugh
  • BIOMARKERS AND METHODS FOR MEASURING AND MONITORING AXIAL SPONDYLOARTHRITIS ACTIVITY
    Publication number: 20220057394
    Abstract: Biomarkers useful for diagnosing and assessing inflammatory disease activity, for prediction of risk for progressive spinal and joint damage, in particular for axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), and for generating a dataset are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Application
    Filed: September 1, 2021
    Publication date: February 24, 2022
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Paul Scott Eastman, Eric Sasso
  • BIOMARKERS AND METHODS FOR ASSESSING RESPONSE TO INFLAMMATORY DISEASE THERAPY WITHDRAWAL
    Publication number: 20210208139
    Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include placing a subject on a therapeutic regimen and subsequently performing an immunoassay to generate a score based on quantitative data for expression of biomarkers relating to inflammatory biomarkers. The methods further include recommending that the subject either remains on the therapeutic regimen, or is removed from the therapeutic regimen, based on the score.
    Type: Application
    Filed: March 15, 2021
    Publication date: July 8, 2021
    Applicant: CRESCENDO BIOSCIENCE
    Inventor: Eric Sasso
  • Methods for assessing response to inflammatory disease therapy withdrawal
    Patent number: 10983120
    Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include placing a subject on a therapeutic regimen and subsequently performing an immunoassay to generate a score based on quantitative data for expression of biomarkers relating to inflammatory biomarkers. The methods further include recommending that the subject either remains on the therapeutic regimen, or is removed from the therapeutic regimen, based on the score.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: April 20, 2021
    Assignee: Crescendo Bioscience
    Inventor: Eric Sasso
  • BIOMARKERS AND METHODS FOR MEASURING AND MONITORING JUVENILE IDIOPATHIC ARTHRITIS ACTIVITY
    Publication number: 20200300853
    Abstract: Biomarkers useful for assessing inflammatory disease or flare activity, in particular in juvenile idiopathic arthritis, are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Application
    Filed: June 9, 2020
    Publication date: September 24, 2020
    Applicant: CRESCENDO BIOSCIENCE, INC.
    Inventors: Scott Eastman, Eric Sasso
  • ADJUSTED MULTI-BIOMARKER DISEASE ACTIVITY SCORE FOR INFLAMMATORY DISEASE ASSESSMENT
    Publication number: 20200249243
    Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are methods of adjusting disease activity scores to account for variables that can influence such scores.
    Type: Application
    Filed: July 30, 2018
    Publication date: August 6, 2020
    Applicant: MYRIAD GENETICS, INC.
    Inventors: Ching Chang HWANG, David CHERNOFF, Alexander GUTIN, Darl FLAKE, Jerry LANCHBURY, Paul Scott EASTMAN, Eric SASSO
  • Biomarkers and methods for measuring and monitoring juvenile idiopathic arthritis activity
    Patent number: 10718765
    Abstract: Biomarkers useful for assessing inflammatory disease or flare activity, in particular in juvenile idiopathic arthritis, are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: July 21, 2020
    Assignee: CRESCENDO BIOSCIENCE, INC.
    Inventors: Scott Eastman, Eric Sasso
  • BIOMARKERS AND METHODS FOR ASSESSING RESPONSE TO INFLAMMATORY DISEASE THERAPY WITHDRAWAL
    Publication number: 20180217141
    Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include placing a subject on a therapeutic regimen and subsequently performing an immunoassay to generate a score based on quantitative data for expression of biomarkers relating to inflammatory biomarkers. The methods further include recommending that the subject either remains on the therapeutic regimen, or is removed from the therapeutic regimen, based on the score.
    Type: Application
    Filed: March 28, 2018
    Publication date: August 2, 2018
    Inventor: Eric Sasso
  • BIOMARKERS AND METHODS FOR ASSESSING PSORIATIC ARTHRITIS DISEASE ACTIVITY
    Publication number: 20180217143
    Abstract: Provided herein are biomarkers and methods for generating scores useful for assessing psoriatic arthritis (PsA) disease activity in subjects previously diagnosed with PsA. The invention also provides predictive model methods based on the biomarkers, as well as computer systems, software embodiments of the models for scoring and optionally classifying samples, and methods of recommending optimal therapeutic regimens.
    Type: Application
    Filed: March 28, 2018
    Publication date: August 2, 2018
    Inventors: Eric Sasso, Paul Scott Eastman, Rebecca Bolce, Arthur Kavanaugh
  • BIOMARKERS AND METHODS FOR MEASURING AND MONITORING AXIAL SPONDYLOARTHRITIS ACTIVITY
    Publication number: 20170097347
    Abstract: Biomarkers useful for diagnosing and assessing inflammatory disease activity, for prediction of risk for progressive spinal and joint damage, in particular for axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), and for generating a dataset are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Application
    Filed: December 9, 2016
    Publication date: April 6, 2017
    Inventors: Paul Scott Eastman, Eric Sasso
  • BIOMARKERS AND METHODS FOR MEASURING AND MONITORING JUVENILE IDIOPATHIC ARTHRITIS ACTIVITY
    Publication number: 20170016896
    Abstract: Biomarkers useful for assessing inflammatory disease or flare activity, in particular in juvenile idiopathic arthritis, are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Application
    Filed: September 30, 2016
    Publication date: January 19, 2017
    Inventors: Scott Eastman, Eric Sasso