Abstract: Example embodiments relate to a sterile urine collection mechanism for medical diagnostic systems. An example device includes an initial collection component configured to collect a midstream urine sample from a patient. The device also includes a plurality of test strips configured to indicate a condition of the patient at a point of care. In addition, the device includes a sensor configured to capture an image of at least one test strip exposed to a portion of the midstream urine sample. Further, the device includes a computing device configured to analyze the image of the test strip captured by the sensor in order to determine the condition of the patient. Even further, the device includes a motor configured to position the test strip near the sensor. Yet further, the device includes an additional collection component configured to collect an additional portion of the midstream urine sample for central laboratory testing.

Abstract: A medical diagnostic system is provided to automate analysis of samples to predict a medical condition, such as pregnancy or chronic kidney disease. The system may provide test strip usage automation. The medical diagnostic system may include a sample collection component, collection cup contamination protection mechanism, sample volume control component, test strip reader component, which may be manifested as a lateral flow strip reader, flow reader, sample analytic component, data processing component, data communication component, networked data management component, and device cleaning mechanism. A method to automate analysis of samples to predict a medical condition using the medical diagnostic system is also provided.

Abstract: A medical diagnostic system is provided to automate analysis of samples to predict a medical condition, such as pregnancy or chronic kidney disease. The system may provide test strip usage automation. The medical diagnostic system may include a sample collection component, collection cup contamination protection mechanism, sample volume control component, test strip reader component, which may be manifested as a lateral flow strip reader, flow reader, sample analytic component, data processing component, data communication component, networked data management component, and device cleaning mechanism. A method to automate analysis of samples to predict a medical condition using the medical diagnostic system is also provided.

Abstract: The present disclosure relates to automated medical diagnostic systems and methods. One example embodiment includes a system. The system includes a test cartridge, a test strip usable to indicate the presence of one or more patient conditions, and a kiosk configured to receive and process the test cartridge and the test strip. The kiosk includes a vortex mixer; a conveyor belt; a robotic pipette module; an imaging system; a display; and a processor communicative coupled to the vortex mixer, the conveyor belt, the robotic pipette module, the imaging system, and the display. The processor is configured to execute instructions stored within a memory to operate the vortex mixer, the conveyor belt, the robotic pipette module, the imagine system, and the display; to receive the image of the test strip from the imaging system; and to analyze the image to determine whether one or more patient conditions is present.

Abstract: Example embodiments relate to a sterile urine collection mechanism for medical diagnostic systems. An example device includes an initial collection component configured to collect a midstream urine sample from a patient. The device also includes a plurality of test strips configured to indicate a condition of the patient at a point of care. In addition, the device includes a sensor configured to capture an image of at least one test strip exposed to a portion of the midstream urine sample. Further, the device includes a computing device configured to analyze the image of the test strip captured by the sensor in order to determine the condition of the patient. Even further, the device includes a motor configured to position the test strip near the sensor. Yet further, the device includes an additional collection component configured to collect an additional portion of the midstream urine sample for central laboratory testing.

Abstract: A medical diagnostic system is provided to automate analysis of samples to predict a medical condition, such as pregnancy or chronic kidney disease. The system may provide test strip usage automation. The medical diagnostic system may include a sample collection component, collection cup contamination protection mechanism, sample volume control component, test strip reader component, which may be manifested as a lateral flow strip reader, flow reader, sample analytic component, data processing component, data communication component, networked data management component, and device cleaning mechanism. A method to automate analysis of samples to predict a medical condition using the medical diagnostic system is also provided.

Abstract: A method for correcting the signal in an image having a plurality of regions of interest, the method comprising the steps of: (a) providing an image having a plurality of regions of interest, these regions of interest having areas between them; (b) determining a region of correction between at least two regions of interest; (c) calculating a correction signal from the region of correction; and (d) using the correction signal to correct a measured signal from one or more regions of interest.

Abstract: A method for identifying artifacts occurring during a measurement of the concentration of an analyte in a biological sample by means of an apparatus that employs temperature-controlled optical probes, introduces electromagnetic radiation into tissue, and collects and detects radiation emitted at a distance from the point at which the electromagnetic radiation is introduced. The values of intensity of radiation emitted at different wavelengths, at different distances between the light introduction site(s) and the light collection site(s), and at different temperatures are collected and used in the method to generate a relationship between these values and the concentration of an analyte in the tissue or the disease state of a patient. The method involves the use of an algorithm that identifies artifacts in the data resulting from motion of the patient and allows the rejection of data sets that contain these artifacts.

Abstract: A method and system for determining the quantity of an analyte initially present in a chemical and or biological reaction as well as a computer implemented method and system to automate portions of the analysis comprising mathematical or graphical analysis of an amplification reaction.

Abstract: A reaction vessel with a bottom drain opening supporting a selected unpressured head of fluid by the surface tension of the fluid. A device processing zone includes a support for spaced rows of reaction vessels, passages communicating with their drain openings of supported vessels, and a pressure source for selectively draining fluid through the drain openings. Generally horizontal bar magnets are supported for selected vertical movement between the vessel rows. A dispensing head has X discharge openings selectively positionable over X selected reaction vessels. A metering pump mechanism selectively meters X a selected quantity of fluid a bulk supply (where X is at least four), and selectively pumps the metered selected quantities through the drain openings to the selected reaction vessels. Methods of drawing fluid from the vessels using the pressure source, and moving the magnets to form a pellet of analyte are also included.