Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted N-type and/or T-type calcium channel activity, are disclosed. Specifically, a series of compounds containing aryl sulphone derivatives, as exemplified by Formula (I).

Abstract: Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed using a series of compounds containing N-acylated cyclic amines linked to an a?l ring as shown in formula (I).

Abstract: A method and apparatus for reducing friction in a cam buckle for tightening a strap. The cam buckle includes a frame, a brake member, a roller member, a biasing element and a webbed strap. The brake member includes a serrated surface and is rotatably coupled to the frame and pivotal about a first axis. The roller member is rotatably coupled to the frame about a second axis, wherein the first axis and the second axis are substantially parallel to each other. The biasing element is operable to bias the serrated surface of the brake member toward the roller member. The webbed strap is formed from a polymeric material and is operable to be biased between the serrated surface and the roller member so that the brake member biases the webbed strap against the roller member. With this arrangement, when the webbed strap is placed in tension, such tension is maintained by preventing movement of the webbed strap in one direction and allowing movement in a second direction to increase the tension.

Abstract: A fluid treatment housing system for fluid filter elements including a first housing member, a second housing member and an interchangeable mounting plate on which one or more filter elements are mounted. The mounting plate may be a substantially flat plate or a basket type structure to accommodate various inside-out and outside-in filter elements. Additionally, more than one mounting plate may be used in a single system so that the system can include both pre and post fluid treatment.

Abstract: A method and apparatus for reducing friction in a cam buckle for tightening a strap. The cam buckle includes a frame, a brake member, a roller member, a biasing element and a webbed strap. The brake member includes a serrated surface and is rotatably coupled to the frame and pivotal about a first axis. The roller member is rotatably coupled to the frame about a second axis, wherein the first axis and the second axis are substantially parallel to each other. The biasing element is operable to bias the serrated surface of the brake member toward the roller member. The webbed strap is formed from a polymeric material and is operable to be biased between the serrated surface and the roller member so that the brake member biases the webbed strap against the roller member. With this arrangement, when the webbed strap is placed in tension, such tension is maintained by preventing movement of the webbed strap in one direction and allowing movement in a second direction to increase the tension.

Abstract: A filtering apparatus includes a filter vessel having an inlet and an outlet for fluid. A tube sheet is disposed within the filter vessel and separates the inlet from the outlet. A plurality of elongated filter elements extend nonvertically from the tube sheet, each filter element having a first end and a second end farther from the tube sheet than the first end and being at a different height than the first end.

Abstract: A surfboard has ribbed or corrugated side rails for improved strength without an increase in weight. In a first embodiment, the board comprises a rigid, buoyant foam core, over which a rigid shell is formed, the shell having side rails with at least one external longitudinal rib. In a second embodiment, the board comprises an injection-molded plastic shell, into which a buoyant foam material is injected. The shell is formed with at least one internal longitudinal rib along each side rail. A portion of the top surface of the surfboard is covered with a layer of unbroken loop nylon material overlying a layer of closed cell foam material to form a resilient, non-abrasive, slip-resistant, water-repellent mat. A foot piece having a sole portion of unbroken loop nylon material is removably attachable to the mat by a double-sided patch of fibrous hook material.