Patents by Inventor Eric Stanton
Eric Stanton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11779644Abstract: Materials and methods for enhancing the effectiveness of proton radiation therapy (e.g., high linear energy transfer (LET) proton radiation therapy) against tumor cells are provided herein.Type: GrantFiled: September 27, 2021Date of Patent: October 10, 2023Assignees: Humanetics Corporation, Trustees of the University of PennsylvaniaInventors: Adam J. Harvey, Michael D. Kaytor, Keith Cengel, Eric Stanton Diffenderfer
-
Publication number: 20220152201Abstract: Materials and methods for enhancing the effectiveness of proton radiation therapy (e.g., high linear energy transfer (LET) proton radiation therapy) against tumor cells are provided herein.Type: ApplicationFiled: September 27, 2021Publication date: May 19, 2022Inventors: Adam J. Harvey, Michael D. Kaytor, Keith Cengel, Eric Stanton Diffenderfer
-
Publication number: 20220099687Abstract: A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are blood, serum, plasma, urine and the like. The NT-proBNP ELISA assay test employs the sandwich ELISA technique to measure circulating NT-proBNP in human plasma. In order to obtain antibodies with specific binding properties for targeted amino acid sequences within human proBNP, recombinant human proBNP (or rhproBNP) was expressed and purified for use as an immunogen. Polyclonal antibodies (PAb) to specific amino acid sequences were subsequently purified from goat serum by sequential affinity purification. Monoclonal antibodies were raised against specific polypeptides. Recombinant human NT-proBNP (or rhNT-proBNP) was expressed and purified in order to obtain material for use in calibration of a quantitative method for measurement of human NT-proBNP.Type: ApplicationFiled: May 19, 2021Publication date: March 31, 2022Inventors: Michelle Davey, George Jackowski, Peter Kupchak, Eric Stanton
-
Patent number: 11129894Abstract: Materials and methods for enhancing the effectiveness of proton radiation therapy (e.g., high linear energy transfer (LET) proton radiation therapy) against tumor cells are provided herein.Type: GrantFiled: September 28, 2018Date of Patent: September 28, 2021Assignees: - Humanetics Corporation, The Trustees of the University of PennsylvaniaInventors: Adam J. Harvey, Michael D. Kaytor, Keith Cengel, Eric Stanton Diffenderfer
-
Patent number: 11016106Abstract: A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are blood, serum, plasma, urine and the like. The NT-proBNP ELISA assay test employs the sandwich ELISA technique to measure circulating NT-proBNP in human plasma. In order to obtain antibodies with specific binding properties for targeted amino acid sequences within human proBNP, recombinant human proBNP (or rhproBNP) was expressed and purified for use as an immunogen. Polyclonal antibodies (PAb) to specific amino acid sequences were subsequently purified from goat serum by sequential affinity purification. Monoclonal antibodies were raised against specific polypeptides. Recombinant human NT-proBNP (or rhNT-proBNP) was expressed and purified in order to obtain material for use in calibration of a quantitative method for measurement of human NT-proBNP.Type: GrantFiled: June 13, 2016Date of Patent: May 25, 2021Assignee: NEXUS DX, INC.Inventors: Michelle Davey, George Jackowski, Peter Kupchak, Eric Stanton
-
Patent number: 10599007Abstract: Various embodiments of the present technology provide a novel architecture for optical frequency conversion in a waveguide which can be applied to any suitable nonlinear waveguide material and any wavelength. In accordance with some embodiments, phase-matched bends can be used to increase the nonlinear interaction length. For example, the device can begin with a straight waveguide section with a width designed for phase-matching. When the straight waveguide section approaches the end of the chip, a bending waveguide section allows the waveguide to meander back in the opposite direction. Various embodiments of the bend can have a wider or narrower width to eliminate phase-matching for second harmonic generation (SHG) and instead provide a 2? phase-shift between the pump and signal light. Therefore, at the end of the bend, the pump and signal light are in-phase and a phase-matched width will continue the SHG process.Type: GrantFiled: July 17, 2019Date of Patent: March 24, 2020Assignees: The Regents of the University of Colorado, a body corporate, Government of the United States of America, as represented by the Secretary of Commerce National Institute of Standards and TechnologyInventors: Eric Stanton, Jeffrey Chiles
-
Publication number: 20200026148Abstract: Various embodiments of the present technology provide a novel architecture for optical frequency conversion in a waveguide which can be applied to any suitable nonlinear waveguide material and any wavelength. In accordance with some embodiments, phase-matched bends can be used to increase the nonlinear interaction length. For example, the device can begin with a straight waveguide section with a width designed for phase-matching. When the straight waveguide section approaches the end of the chip, a bending waveguide section allows the waveguide to meander back in the opposite direction. Various embodiments of the bend can have a wider or narrower width to eliminate phase-matching for second harmonic generation (SHG) and instead provide a 2? phase-shift between the pump and signal light. Therefore, at the end of the bend, the pump and signal light are in-phase and a phase-matched width will continue the SHG process.Type: ApplicationFiled: July 17, 2019Publication date: January 23, 2020Applicant: The Regents of the University of Colorado, a body corporateInventors: Eric Stanton, Jeffrey Chiles
-
Patent number: 10333011Abstract: Resonant-cavity infrared photodetector (RCID) devices that include a thin absorber layer contained entirely within the resonant cavity. In some embodiments, the absorber is a single type-II InAs—GaSb interface situated between an AlSb/InAs superlattice n-type region and a p-type AlSb/GaSb region. In other embodiments, the absorber region comprises quantum wells formed on an upper surface of the n-type region. In other embodiments, the absorber region comprises a “W”-structured quantum well situated between two barrier layers, the “W”-structured quantum well comprising a hole quantum well sandwiched between two electron quantum wells. In other embodiments, the RCID includes a thin absorber region and an nBn or pBp active core within a resonant cavity. In some embodiments, the RCID is configured to absorb incident light propagating in the direction of the epitaxial growth of the RCID structure, while in other embodiments, it absorbs light propagating in the epitaxial plane of the structure.Type: GrantFiled: July 10, 2018Date of Patent: June 25, 2019Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Jerry R. Meyer, Igor Vurgaftman, Chadwick Lawrence Canedy, William W. Bewley, Chul Soo Kim, Charles D. Merritt, Michael V. Warren, Mijin Kim, Eric Stanton
-
Publication number: 20190099491Abstract: Materials and methods for enhancing the effectiveness of proton radiation therapy (e.g., high linear energy transfer (LET) proton radiation therapy) against tumor cells are provided herein.Type: ApplicationFiled: September 28, 2018Publication date: April 4, 2019Inventors: Adam J. Harvey, Michael D. Kaytor, Keith Cengel, Eric Stanton Diffenderfer
-
Publication number: 20180331237Abstract: Resonant-cavity infrared photodetector (RCID) devices that include a thin absorber layer contained entirely within the resonant cavity. In some embodiments, the absorber is a single type-II InAs—GaSb interface situated between an AlSb/InAs superlattice n-type region and a p-type AlSb/GaSb region. In other embodiments, the absorber region comprises quantum wells formed on an upper surface of the n-type region. In other embodiments, the absorber region comprises a “W”-structured quantum well situated between two barrier layers, the “W”-structured quantum well comprising a hole quantum well sandwiched between two electron quantum wells. In other embodiments, the RCID includes a thin absorber region and an nBn or pBp active core within a resonant cavity. In some embodiments, the RCID is configured to absorb incident light propagating in the direction of the epitaxial growth of the RCID structure, while in other embodiments, it absorbs light propagating in the epitaxial plane of the structure.Type: ApplicationFiled: July 10, 2018Publication date: November 15, 2018Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Jerry R. Meyer, Igor Vurgaftman, Chadwick Lawrence Canedy, William W. Bewley, Chul Soo Kim, Charles D. Merritt, Michael V. Warren, Mijin Kim, Eric Stanton
-
Ultra-broadband photonic integrated circuit platform and ultra-broadband photonic integrated circuit
Patent number: 9612398Abstract: An ultra-broadband photonic integrated circuit platform that combines at least two types of waveguides that each transmit in different, but overlapping, spectral bands on a single chip. By combining the multiple waveguides, the bandwidth of the platform can be extended beyond the bandwidth of either waveguide alone. In an exemplary embodiment, an ultra-broadband photonic integrated circuit includes a nitride-on-insulator (NOI) waveguide configured to transmit optical beams in a first spectral band and a silicon-on-nitride-on-insulator (SONOI) waveguide configured to transmit optical beams in a second band, where the same material serves as the core material in the NOI waveguide and as the cladding material in the SONOI waveguide. In some embodiments, light-emitting devices are bonded to an upper surface of the waveguides. In some embodiments, the circuit includes beam-combining elements so that a single beam combining all of the input wavelengths is output from the circuit.Type: GrantFiled: October 16, 2015Date of Patent: April 4, 2017Assignee: The United States of America, as represented by the Secretary of the NavyInventors: Igor Vurgaftman, Jerry R. Meyer, Martijn Heck, Jock Bovington, Alexander Spott, Eric Stanton, John Bowers -
Publication number: 20170010288Abstract: A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are blood, serum, plasma, urine and the like. The NT-proBNP ELISA assay test employs the sandwich ELISA technique to measure circulating NT-proBNP in human plasma. In order to obtain antibodies with specific binding properties for targeted amino acid sequences within human proBNP, recombinant human proBNP (or rhproBNP) was expressed and purified for use as an immunogen. Polyclonal antibodies (PAb) to specific amino acid sequences were subsequently purified from goat serum by sequential affinity purification. Monoclonal antibodies were raised against specific polypeptides. Recombinant human NT-proBNP (or rhNT-proBNP) was expressed and purified in order to obtain material for use in calibration of a quantitative method for measurement of human NT-proBNP.Type: ApplicationFiled: June 13, 2016Publication date: January 12, 2017Inventors: Michelle Davey, George Jackowski, Peter Kupchak, Eric Stanton
-
Patent number: 9371382Abstract: A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are blood, serum, plasma, urine and the like.Type: GrantFiled: September 19, 2011Date of Patent: June 21, 2016Assignee: Nexus DX, Inc.Inventors: Michelle Davey, George Jackowski, Peter Kupchak, Eric Stanton
-
Ultra-Broadband Photonic Integrated Circuit Platform and Ultra-Broadband Photonic Integrated Circuit
Publication number: 20160109655Abstract: An ultra-broadband photonic integrated circuit platform that combines at least two types of waveguides that each transmit in different, but overlapping, spectral bands on a single chip. By combining the multiple waveguides, the bandwidth of the platform can be extended beyond the bandwidth of either waveguide alone. In an exemplary embodiment, an ultra-broadband photonic integrated circuit includes a nitride-on-insulator (NOI) waveguide configured to transmit optical beams in a first spectral band and a silicon-on-nitride-on-insulator (SONOI) waveguide configured to transmit optical beams in a second band, where the same material serves as the core material in the NOI waveguide and as the cladding material in the SONOI waveguide. In some embodiments, light-emitting devices are bonded to an upper surface of the waveguides. In some embodiments, the circuit includes beam-combining elements so that a single beam combining all of the input wavelengths is output from the circuit.Type: ApplicationFiled: October 16, 2015Publication date: April 21, 2016Applicant: The Government of the United States of America, as represented by the Secretary of the NavyInventors: Igor Vurgaftman, Jerry R. Meyer, Martijn Heck, Jock Bovington, Alexander Spott, Eric Stanton, John Bowers -
Publication number: 20120107848Abstract: A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are blood, serum, plasma, urine and the like. The NT-proBNP ELISA assay test employs the sandwich ELISA technique to measure circulating NT-proBNP in human plasma. In order to obtain antibodies with specific binding properties for targeted amino acid sequences within human proBNP, recombinant human proBNP (or rhproBNP) was expressed and purified for use as an immunogen. Polyclonal antibodies (PAb) to specific amino acid sequences were subsequently purified from goat serum by sequential affinity purification. Monoclonal antibodies were raised against specific polypeptides. Recombinant human NT-proBNP (or rhNT-proBNP) was expressed and purified in order to obtain material for use in calibration of a quantitative method for measurement of human NT-proBNP.Type: ApplicationFiled: September 19, 2011Publication date: May 3, 2012Applicant: Nexus Dx, Inc.Inventors: Michelle DAVEY, George JACKOWSKI, Peter KUPCHAK, Eric STANTON
-
Publication number: 20090325195Abstract: A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are blood, serum, plasma, urine and the like. The NT-proBNP ELISA assay test employs the sandwich ELISA technique to measure circulating NT-proBNP in human plasma. In order to obtain antibodies with specific binding properties for targeted amino acid sequences within human proBNP, recombinant human proBNP (or rhproBNP) was expressed and purified for use as an immunogen. Polyclonal antibodies (PAb) to specific amino acid sequences were subsequently purified from goat serum by sequential affinity purification. Monoclonal antibodies were raised against specific polypeptides. Recombinant human NT-proBNP (or rhNT-proBNP) was expressed and purified in order to obtain material for use in calibration of a quantitative method for measurement of human NT-proBNP.Type: ApplicationFiled: April 9, 2009Publication date: December 31, 2009Inventors: Michelle Davey, George Jackowski, Peter Kupchak, Eric Stanton
-
Patent number: 7527939Abstract: A specific and sensitive in vitro ELISA assay and diagnostic test kit is disclosed for determining levels of NT-proBNP protein in a variety of bodily fluids, non-limiting examples of which are blood, serum, plasma, urine and the like. The NT-proBNP ELISA assay test employs the sandwich ELISA technique to measure circulating NT-proBNP in human plasma. In order to obtain antibodies with specific binding properties for targeted amino acid sequences within human proBNP, recombinant human proBNP (or rhproBNP) was expressed and purified for use as an immunogen. Polyclonal antibodies (PAb) to specific amino acid sequences were subsequently purified from goat serum by sequential affinity purification. Monoclonal antibodies were raised against specific polypeptides. Recombinant human NT-proBNP (or rhNT-proBNP) was expressed and purified in order to obtain material for use in calibration of a quantitative method for measurement of human NT-proBNP.Type: GrantFiled: March 13, 2006Date of Patent: May 5, 2009Assignee: Nanogen, Inc.Inventors: Michelle Davey, George Jackowski, Peter Kupchak, Eric Stanton
-
Patent number: 7421710Abstract: Disclosed is a system and method for transmitting computer data within a single computer system along more than one physical data path by providing a multiple-path driver that creates virtual (or non-physical) data paths without modifying the source code of the operating system. The system and method may be used with any computer hardware regardless of manufacturer. In one embodiment, a multiple-path driver may be used within a Linux operating system to create virtual data paths and transmit data between the upper-level drivers of the Linux system and at least one computer data storage device without modifying the Linux source code.Type: GrantFiled: October 8, 2003Date of Patent: September 2, 2008Assignee: LSI CorporationInventors: Yanling Qi, Eric Stanton
-
Publication number: 20070184507Abstract: The invention describes methods for predicting outcome for patients suffering from traumatic brain injury (TBI) by evaluating levels of markers commonly associated with cellular damage in bodily fluids. Utilization of such methods improves diagnosis and treatment of patients suffering from traumatic brain injury, thus potentially minimizing and/or eliminating long-term adverse effects in these patients.Type: ApplicationFiled: April 19, 2007Publication date: August 9, 2007Inventors: George Jackowski, Eric Stanton, Petro Kupchak, Miyoko Takahashi, Michelle Davey
-
Patent number: D697166Type: GrantFiled: October 2, 2012Date of Patent: January 7, 2014Inventor: Eric Stanton Martinson