Patents by Inventor Eric Stern

Eric Stern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12352540
    Abstract: Disclosed herein apparatus and associated methods relate to body armor comprising a plate having a ceramic tile bonded to front and back polyolefin layers by front and back pretreated prepreg layers. The pretreated prepreg layers may comprise epoxy resin sheets precooled for storage at 0° F. The polyolefin layers may comprise 940 and 1880 denier extruded polyolefin sheets. The stored cold prepreg sheets may be heated and the hot prepreg sheets used to join the ceramic tile with the extruded polyolefin sheets. The ceramic tile may be bonded to the extruded polyolefin sheets by cooling the ceramic tile, extruded polyolefin sheets and hot prepreg sheets in a ?58° F. freezer, forming a cooled bonded plate. A backer comprising stacked plastic sheets may be connected to the plate. The cooled bonded plate may be cured by a curing cycle comprising 260° F. and 120 PSI using an autoclave.
    Type: Grant
    Filed: January 18, 2025
    Date of Patent: July 8, 2025
    Assignee: 8910 LLC
    Inventors: Mario Colon, Scott Spratt, Eric Stern
  • Publication number: 20250172371
    Abstract: Disclosed herein apparatus and associated methods relate to body armor comprising a plate having a ceramic tile bonded to front and back polyolefin layers by front and back pretreated prepreg layers. The pretreated prepreg layers may comprise epoxy resin sheets precooled for storage at 0° F. The polyolefin layers may comprise 940 and 1880 denier extruded polyolefin sheets. The stored cold prepreg sheets may be heated and the hot prepreg sheets used to join the ceramic tile with the extruded polyolefin sheets. The ceramic tile may be bonded to the extruded polyolefin sheets by cooling the ceramic tile, extruded polyolefin sheets and hot prepreg sheets in a ?58° F. freezer, forming a cooled bonded plate. A backer comprising stacked plastic sheets may be connected to the plate. The cooled bonded plate may be cured by a curing cycle comprising 260° F. and 120 PSI using an autoclave.
    Type: Application
    Filed: January 18, 2025
    Publication date: May 29, 2025
    Inventors: Mario Colon, Scott Spratt, Eric Stern
  • Patent number: 12312632
    Abstract: Phenotypic antimicrobial susceptibility testing (AST), the gold-standard diagnostic that indicates whether an antimicrobial will be clinically effective, often suffer the slowest times-to-result for the most resistant pathogens. Here we introduce novel assays to be performed in parallel with standard AST assays that provide additional resistance information and enable rapid, same-shift reporting of AST results for a plurality of pathogens.
    Type: Grant
    Filed: November 1, 2023
    Date of Patent: May 27, 2025
    Assignee: SeLux Diagnostics, Inc.
    Inventors: Kelly Flentie, Eric Stern
  • Patent number: 12235083
    Abstract: Disclosed herein apparatus and associated methods relate to body armor comprising a plate having a ceramic tile bonded to front and back polyolefin layers by front and back pretreated prepreg layers. The pretreated prepreg layers may comprise epoxy resin sheets precooled for storage at 0° F. The polyolefin layers may comprise 940 and 1880 denier extruded polyolefin sheets. The stored cold prepreg sheets may be heated and the hot prepreg sheets used to join the ceramic tile with the extruded polyolefin sheets. The ceramic tile may be bonded to the extruded polyolefin sheets by cooling the ceramic tile, extruded polyolefin sheets and hot prepreg sheets in a ?58° F. freezer, forming a cooled bonded plate. A backer comprising stacked plastic sheets may be connected to the plate. The cooled bonded plate may be cured by a curing cycle comprising 260° F. and 120 PSI using an autoclave.
    Type: Grant
    Filed: March 12, 2024
    Date of Patent: February 25, 2025
    Assignee: 8910 LLC
    Inventors: Mario Colon, Scott Spratt, Eric Stern
  • Publication number: 20250034615
    Abstract: An improved system, method and interface for automated rapid antimicrobial susceptibility testing (AST) is disclosed which includes, in one aspect, a carrier population station comprising a workstation having a graphic user interface (GUI). The GUI accepts information from a lab technologist, including information related to a scope of testing to be performed on a patient sample. The GUI controls intelligent assignment of patient samples to test panels in a manner that maximize utilization of the test carrier by grouping together samples of similar tests scopes and advantageously testing those samples using one multiplexed test panel. Customizing workflow in accordance with test scope to facilitate parallel processing of multiple samples advantageously reduces laboratory waste, decreases test latencies, increases AST system throughput and efficiency, and thus lowers the costs to the AST lab.
    Type: Application
    Filed: October 16, 2024
    Publication date: January 30, 2025
    Inventors: Kelly Flentie, Eric Stern
  • Patent number: 12203124
    Abstract: The present invention provides for improved antimicrobial susceptibility testing and more specifically for improved rapid antimicrobial susceptibility testing of clinical samples for efficient and versatile analysis and reliable results.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: January 21, 2025
    Assignee: SELUX DIAGNOSTICS, INC.
    Inventors: Eric Stern, Aleksandar Vacic, Kelly Flentie, Benjamin Spears, Felicia Chen
  • Patent number: 12156939
    Abstract: A “nanolipogel” is a delivery vehicle including one or more lipid layer surrounding a hydrogel core, which may include an absorbent such as a cyclodextrin or ion-exchange resin. Nanolipogels can be constructed so as to incorporate a variety of different chemical entities that can subsequently be released in a controlled fashion. These different incorporated chemical entities can differ dramatically with respect to size and composition. Nanolipogels have been constructed to contain co-encapsulated proteins as well as small hydrophobic drugs within the interior of the lipid bilayer. Agents incorporated within nanolipogels can be released into the milieu in a controlled fashion, for example, nanolipogels provide a means of achieving simultaneous sustained release of agents that differ widely in chemical composition and molecular weight. Additionally, nanolipogels can favorably modulate biodistribution.
    Type: Grant
    Filed: August 11, 2021
    Date of Patent: December 3, 2024
    Assignee: Yale University
    Inventors: Tarek M. Fahmy, Eric Stern, Richard A. Flavell, Jason Park, Alyssa Siefert, Stephen H. Wrzesinski
  • Patent number: 12129510
    Abstract: An improved system, method and interface for automated rapid antimicrobial susceptibility testing (AST) is disclosed which includes, in one aspect, a carrier population station comprising a workstation having a graphic user interface (GUI). The GUI accepts information from a lab technologist, including information related to a scope of testing to be performed on a patient sample. The GUI controls intelligent assignment of patient samples to test panels in a manner that maximize utilization of the test carrier by grouping together samples of similar tests scopes and advantageously testing those samples using one multiplexed test panel. Customizing workflow in accordance with test scope to facilitate parallel processing of multiple samples advantageously reduces laboratory waste, decreases test latencies, increases AST system throughput and efficiency, and thus lowers the costs to the AST lab.
    Type: Grant
    Filed: November 30, 2023
    Date of Patent: October 29, 2024
    Assignee: SeLux Diagnostics, Inc.
    Inventors: Kelly Flentie, Eric Stern
  • Publication number: 20240167073
    Abstract: An improved system, method and interface for automated rapid antimicrobial susceptibility testing (AST) is disclosed which includes, in one aspect, a carrier population station comprising a workstation having a graphic user interface (GUI). The GUI accepts information from a lab technologist, including information related to a scope of testing to be performed on a patient sample. The GUI controls intelligent assignment of patient samples to test panels in a manner that maximize utilization of the test carrier by grouping together samples of similar tests scopes and advantageously testing those samples using one multiplexed test panel. Customizing workflow in accordance with test scope to facilitate parallel processing of multiple samples advantageously reduces laboratory waste, decreases test latencies, increases AST system throughput and efficiency, and thus lowers the costs to the AST lab.
    Type: Application
    Filed: November 30, 2023
    Publication date: May 23, 2024
    Inventors: Kelly Flentie, Eric Stern
  • Publication number: 20240102074
    Abstract: Phenotypic antimicrobial susceptibility testing (AST), the gold-standard diagnostic that indicates whether an antimicrobial will be clinically effective, often suffer the slowest times-to-result for the most resistant pathogens. Here we introduce novel assays to be performed in parallel with standard AST assays that provide additional resistance information and enable rapid, same-shift reporting of AST results for a plurality of pathogens.
    Type: Application
    Filed: November 1, 2023
    Publication date: March 28, 2024
    Inventors: Kelly Flentie, Eric Stern
  • Publication number: 20240069049
    Abstract: In some aspects, automated rapid antimicrobial susceptibility testing systems for performing a multi-assay testing sequence can include an automated incubation assembly having a nest assembly adapted to house at least one test panel having a plurality of wells for receiving a sample comprising microorganisms originating from a clinical sample, the incubation assembly facilitating incubation of one or more test panels in order to undergo the multi-assay testing sequence; a robotic handling assembly configured to accept one or more incoming test panels and move them to and from the incubation assembly for incubation between each assay of the multi-assay testing sequence; an automated liquid handling assembly configured to exchange one or more fluids in the plurality of wells of the test panels; and an optical assembly for interrogation and readout of each assay of the multi-assay testing sequence being performed in the plurality of wells.
    Type: Application
    Filed: October 17, 2023
    Publication date: February 29, 2024
    Inventors: Aleksandar Vacic, Nathan Purmort, Eric Stern, Anna Passernig, Paul Otten, Randy Tragni, Ronan Hayes, Andriy Tsupryk, Bruce Richardson
  • Patent number: 11866763
    Abstract: An improved system, method and interface for automated rapid antimicrobial susceptibility testing (AST) is disclosed which includes, in one aspect, a carrier population station comprising a workstation having a graphic user interface (GUI). The GUI accepts information from a lab technologist, including information related to a scope of testing to be performed on a patient sample. The GUI controls intelligent assignment of patient samples to test panels in a manner that maximize utilization of the test carrier by grouping together samples of similar tests scopes and advantageously testing those samples using one multiplexed test panel. Customizing workflow in accordance with test scope to facilitate parallel processing of multiple samples advantageously reduces laboratory waste, decreases test latencies, increases AST system throughput and efficiency, and thus lowers the costs to the AST lab.
    Type: Grant
    Filed: November 14, 2019
    Date of Patent: January 9, 2024
    Assignee: SELUX DIAGNOSTICS, INC.
    Inventors: Kelly Flentie, Eric Stern
  • Patent number: 11845976
    Abstract: Phenotypic antimicrobial susceptibility testing (AST), the gold-standard diagnostic that indicates whether an antimicrobial will be clinically effective, often suffer the slowest times-to-result for the most resistant pathogens. Here we introduce novel assays to be performed in parallel with standard AST assays that provide additional resistance information and enable rapid, same-shift reporting of AST results for a plurality of pathogens.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: December 19, 2023
    Assignee: SELUX DIAGNOSTICS, INC.
    Inventors: Kelly Flentie, Eric Stern
  • Patent number: 11835523
    Abstract: Phenotypic antimicrobial susceptibility testing (AST), the gold-standard diagnostic that indicates whether an antimicrobial will be clinically effective, often suffer the slowest times-to-result for the most resistant pathogens. Here we introduce novel assays to be performed in parallel with standard AST assays that enable rapid, same-shift reporting of AST results for a plurality of pathogens. The assays developed here are further capable of detecting resistance to carbapenems, the most powerful class of beta-lactams commonly used as “last-resort” antimicrobials.
    Type: Grant
    Filed: February 15, 2022
    Date of Patent: December 5, 2023
    Assignee: SELUX DIAGNOSTICS, INC.
    Inventors: Eric Stern, Kelly Flentie, Nicholas Phelan
  • Patent number: 11828766
    Abstract: In some aspects, automated rapid antimicrobial susceptibility testing systems for performing a multi-assay testing sequence can include an automated incubation assembly having a nest assembly adapted to house at least one test panel having a plurality of wells for receiving a sample comprising microorganisms originating from a clinical sample, the incubation assembly facilitating incubation of one or more test panels in order to undergo the multi-assay testing sequence; a robotic handling assembly configured to accept one or more incoming test panels and move them to and from the incubation assembly for incubation between each assay of the multi-assay testing sequence; an automated liquid handling assembly configured to exchange one or more fluids in the plurality of wells of the test panels; and an optical assembly for interrogation and readout of each assay of the multi-assay testing sequence being performed in the plurality of wells.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: November 28, 2023
    Assignee: SELUX DIAGNOSTICS, INC.
    Inventors: Aleksandar Vacic, Nathan Purmort, Eric Stern, Anna Passernig, Paul Otten, Randy Tragni, Ronan Hayes, Andriy Tsupryk, Bruce Richardson
  • Publication number: 20230330677
    Abstract: The present disclosure relates generally to devices, systems, and methods for sample tube processing and more specifically to antimicrobial susceptibility testing, including automated systems capable of separating viable microbes from positive blood cultures. In an aspect, a sample tube may include a container comprising an open first end, a closed second end, and a tubular wall extending substantially along a longitudinal axis of the container. A protrusion may extend radially from an external surface of the tubular wall. A cap may be reversibly coupled to the first end of the container. The cap may include an interface ring having a top side, an underside, and a central axis therethrough. A skirt portion may extend from the underside substantially parallel with the central axis. A sealing wall may extend from the underside. A channel may be between the skirt portion and the sealing wall configured to reversibly accept the tubular wall.
    Type: Application
    Filed: September 8, 2021
    Publication date: October 19, 2023
    Applicant: SELUX DIAGNOSTICS, INC.
    Inventors: Matthew Briscoe, Mark Mooradian, Eric Stern
  • Patent number: 11390900
    Abstract: The present invention provides, among other things, cartridges for multiplexed antimicrobial susceptibility testing (AST), single cartridges useful for both AST and quality control of AST, and systems and methods relating thereto.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: July 19, 2022
    Assignee: SELUX DIAGNOSTICS, INC.
    Inventors: Eric Stern, Kelly Flentie, Aleksandar Vacic, Frederick P. Floyd, Sarah A. Scott
  • Publication number: 20220170934
    Abstract: Phenotypic antimicrobial susceptibility testing (AST), the gold-standard diagnostic that indicates whether an antimicrobial will be clinically effective, often suffer the slowest times-to-result for the most resistant pathogens. Here we introduce novel assays to be performed in parallel with standard AST assays that enable rapid, same-shift reporting of AST results for a plurality of pathogens. The assays developed here are further capable of detecting resistance to carbapenems, the most powerful class of beta-lactams commonly used as “last-resort” antimicrobials.
    Type: Application
    Filed: February 15, 2022
    Publication date: June 2, 2022
    Inventors: Eric Stern, Kelly Flentie, Nicholas Phelan
  • Patent number: 11339418
    Abstract: Systems and methods for microbe identification (ID) in the context of phenotypic antimicrobial susceptibility testing (AST). Approaches for rapidly identifying polymicrobial samples are introduced that following perform one or more ID methods, such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF), PCR, or DNA hybridization, following sample incubation in two or more different media, including at least one selective media. Parallel ID and AST workflows are provided that may reduce the time from sample to AST result.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: May 24, 2022
    Assignee: SELUX DIAGNOSTICS, INC.
    Inventors: Eric Stern, Kelly Flentie, Kristin Baker
  • Publication number: 20220145352
    Abstract: An improved system, method and interface for automated rapid antimicrobial susceptibility testing (AST) is disclosed which includes, in one aspect, a carrier population station comprising a workstation having a graphic user interface (GUI). The GUI accepts information from a lab technologist, including information related to a scope of testing to be performed on a microorganism containing sample. The GUI controls intelligent assignment of microorganism containing samples to test panels in a manner that maximize utilization of the test carrier by grouping together samples of similar tests scopes and advantageously testing those samples using one multiplexed test panel. Customizing workflow in accordance with test scope to facilitate parallel processing of multiple samples advantageously reduces laboratory waste, decreases test latencies, increases AST system throughput and efficiency, and thus lowers the costs to the AST lab.
    Type: Application
    Filed: January 21, 2022
    Publication date: May 12, 2022
    Inventors: Eric Stern, Kelly Flentie, Aleksandar Vacic, Frederick P. Floyd, JR.