Abstract: A method of training an artificial neural network to predict gene expression for a patient having a pathological condition is provided. The method comprises obtaining a set of histopathological images from a database of patients having the pathological condition, collecting from the database a set of gene expression profiles corresponding to the histopathological images, identifying in the set of gene expression profiles a set of considered genes, selecting a training subset of the considered genes comprising genes characterized by similar median gene expression values, and training the neural network to predict a gene expression value of an input histopathological image, using gene expression profiles of the genes in the training subset simultaneously.

Abstract: A system and method for providing customized content recommendations to a user based on extrapolated data is described. The system may receive an answer to a question from a user and determine a second unanswered question having a threshold relationship level with the question. The system may compute a predicted probability that the user would answer the second question correctly, calculate a first comparative skill level of the user among a cohort of similar users, and rank the first comparative skill level of the user against a second comparative skill level of the cohort to determine a skill gap of the user. Further, in some implementations, the system may generate a search query based on the skill gap of the user, and determine recommended content customized to the skill gap of the user.

Abstract: A system and method for providing customized content recommendations to a user based on extrapolated data is described. The system may receive an answer to a question from a user and determine a second unanswered question having a threshold relationship level with the question. The system may compute a predicted probability that the user would answer the second question correctly, calculate a first comparative skill level of the user among a cohort of similar users, and rank the first comparative skill level of the user against a second comparative skill level of the cohort to determine a skill gap of the user. Further, in some implementations, the system may generate a search query based on the skill gap of the user, and determine recommended content customized to the skill gap of the user.

Abstract: Apparatus configured for attachment to a spackle container and provide thereby a surface for working spackling compound while substantially sealing the spackle container.

Abstract: A spackle container lid is disclosed. The spackle container lid comprises a flat working surface on the top thereof that is used as a surface for the worker.