Abstract: A wellbeing system configured for assessing a mental wellbeing of a driver while driving the vehicle and deploying a countermeasure in response to a mindfulness level of the driver being beyond a desired range. The countermeasure may be configured to mitigate a probability of a mental wellbeing of the driver undesirably impacting operation of the vehicle.

Abstract: Methods for treating a patient are provided. These methods may include receiving scan data of a patient's teeth, forming a modified image of the teeth to simulate a dental treatment, combining the modified image of the teeth with an image of the patient's face to show an image of the patient's smile as it would appear according to the dental treatment, displaying the modified image to the patient, and treating the patient according to the simulated dental treatment.

Abstract: A method of using a catheter assembly for inserting in a fluid filled space in a body includes providing a main body having a first end portion and a second end portion. The first end portion is positioned within the fluid filled space. The second end portion is adjusted to extend outwardly from the fluid filled space when the first end portion is positioned within the fluid filled space. A catheter tip is connected to the second end portion of the main body. The catheter tip includes a housing having a cavity defined therein and a rotating element positioned within the fluid filled space. The rotating element is rotated within the cavity of the housing to impart movement of the first end portion of the main body within the fluid filled space.

Abstract: A system and method for providing customized content recommendations to a user based on extrapolated data is described. The system may receive an answer to a question from a user and determine a second unanswered question having a threshold relationship level with the question. The system may compute a predicted probability that the user would answer the second question correctly, calculate a first comparative skill level of the user among a cohort of similar users, and rank the first comparative skill level of the user against a second comparative skill level of the cohort to determine a skill gap of the user. Further, in some implementations, the system may generate a search query based on the skill gap of the user, and determine recommended content customized to the skill gap of the user.

Abstract: A system and method for providing customized content recommendations to a user based on extrapolated data is described. The system may receive an answer to a question from a user and determine a second unanswered question having a threshold relationship level with the question. The system may compute a predicted probability that the user would answer the second question correctly, calculate a first comparative skill level of the user among a cohort of similar users, and rank the first comparative skill level of the user against a second comparative skill level of the cohort to determine a skill gap of the user. Further, in some implementations, the system may generate a search query based on the skill gap of the user, and determine recommended content customized to the skill gap of the user.

Abstract: Pharmaceutical compositions containing a cocktail of inhibitors of central stress nuclei are provided. The pharmaceutical compositions are useful for the prevention and treatment of a variety of conditions in mammals including humans, including anxiety and mood disorders such as depression.

Abstract: Compounds and pharmaceutical compositions containing such compounds having formula I are provided: where R1, R2a, R2b, R3, R4, and R5 are as defined herein. The compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including anxiety and mood disorders such as depression.

Abstract: Pharmaceutical compositions containing a cocktail of inhibitors of central stress nuclei are provided. The pharmaceutical compositions are useful for the prevention and treatment of a variety of conditions in mammals including humans, including anxiety and mood disorders such as depression.

Abstract: Compounds and pharmaceutical compositions containing such compounds having formula I are provided: where R1, R2a, R2b, R3, R4, and R5 are as defined herein. The compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including anxiety and mood disorders such as depression.

Abstract: Apparatus configured for attachment to a spackle container and provide thereby a surface for working spackling compound while substantially sealing the spackle container.

Abstract: A spackle container lid is disclosed. The spackle container lid comprises a flat working surface on the top thereof that is used as a surface for the worker.

Abstract: The treatment of neurodegenerative diseases by the stimulation of endogenous or recombinant expression in vivo of nerve growth factor in the central nervous system by administration of a therapeutically effective amount of an .alpha..sub.2 -antagonist.