Patents by Inventor Eric SULPICE

Eric SULPICE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SIRNA SEQUENCES TARGETING THE EXPRESSION OF HUMAN GENES JAK1 OR JAK3 FOR A THERAPEUTIC USE
    Publication number: 20220298512
    Abstract: A double-stranded (ds) ribonucleic acid (RNA) comprising a sense strand and an antisense strand, wherein: the sense strand comprises the nucleotide sequence SEQ ID NO: 1 and the antisense strand comprises the nucleotide sequence SEQ ID NO: 2; or the sense stand comprises the nucleotide sequence SEQ ID NO: 3 and the antisense strand comprises the nucleotide sequence SEQ ID NO: 4; or the sense strand comprises the nucleotide sequence SEQ ID NO: 5 and the antisense strand comprises the nucleotide sequence SEQ ID NO: 6; or the sense strand comprises the nucleotide sequence SEQ ID NO: 7 and the antisense strand comprises the nucleotide sequence SEQ ID NO: 8. The dsRNA therefrom may be used as a drug.
    Type: Application
    Filed: July 13, 2020
    Publication date: September 22, 2022
    Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Flora CLEMENT, Eric SULPICE, Xavier GIDROL
  • High-throughput screening method for the identification of biomarkers, therapeutic targets or therapeutic agents
    Patent number: 10597700
    Abstract: The present invention relates to a method for screening a molecule of interest by means of nanoparticles comprising a candidate molecule, a tracer, and a single DNA tag specific to said molecule. The present invention also relates to a method for screening biomarkers of a disease and/or of a phenotype feature, more particularly of a cancer or an infection, by means of said nanoparticles. The invention finally relates to the nanoparticles as such as well as to a library of said nanoparticles.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: March 24, 2020
    Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Fabrice Navarro Y Garcia, Jonathan Bruniaux, Xavier Gidrol, Eric Sulpice
  • Method for transfection of nucleic acids into eukaryotic cells in 3D scaffold
    Patent number: 10253315
    Abstract: The present invention concerns a method for in vitro or ex vivo transfection of a nucleic acid into a eukaryotic cell in 3D scaffold by contacting eukaryotic cells in 3D scaffold with a formulation in nanoemulsion form which comprises a continuous aqueous phase and a least one dispersed phase, and which comprises said nucleic acid. The invention further relates to a method of screening implementing said method of transfection, and to 3D scaffold comprising eukaryotic cells and said formulation in nanoemulsion form which comprises a continuous aqueous phase and a least one dispersed phase, and which comprises said nucleic acid.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: April 9, 2019
    Assignee: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Jonathan Bruniaux, Xavier Gidrol, Fabrice Navarro Y Garcia, Eric Sulpice
  • HIGH-THROUGHPUT SCREENING METHOD FOR THE IDENTIFICATION OF BIOMARKERS, THERAPEUTIC TARGETS OR THERAPEUTIC AGENTS
    Publication number: 20150322494
    Abstract: The present invention relates to a method for screening a molecule of interest by means of nanoparticles comprising a candidate molecule, a tracer, and a single DNA tag specific to said molecule. The present invention also relates to a method for screening biomarkers of a disease and/or of a phenotype feature, more particularly of a cancer or an infection, by means of said nanoparticles. The invention finally relates to the nanoparticles as such as well as to a library of said nanoparticles.
    Type: Application
    Filed: December 2, 2013
    Publication date: November 12, 2015
    Inventors: Fabrice NAVARRO Y GARCIA, Jonathan BRUNIAUX, Xavier GIDROL, Eric SULPICE
  • Formulation for the Delivery of Nucleotide Sequences That Can Modulate Endogenous Interfering RNA Mechanisms
    Publication number: 20150258022
    Abstract: The present invention concerns a formulation in nanoemulsion form comprising a continuous aqueous phase and at least one dispersed phase, useful as system for delivering nucleotide sequences able to modulate endogenous mechanisms of RNA interference or as transfecting agent.
    Type: Application
    Filed: August 12, 2013
    Publication date: September 17, 2015
    Inventors: Fabrice Navarro Y Garcia, Jonathan Bruniaux, Xavier Gidrol, Eric Sulpice, Isabelle Texier-Nogues
  • METHOD FOR TRANSFECTION OF NUCLEIC ACIDS INTO EUKARYOTIC CELLS IN 3D SCAFFOLD
    Publication number: 20150159153
    Abstract: The present invention concerns a method for in vitro or ex vivo transfection of a nucleic acid into a eukaryotic cell in 3D scaffold by contacting eukaryotic cells in 3D scaffold with a formulation in nanoemulsion form which comprises a continuous aqueous phase and a least one dispersed phase, and which comprises said nucleic acid. The invention further relates to a method of screening implementing said method of transfection, and to 3D scaffold comprising eukaryotic cells and said formulation in nanoemulsion form which comprises a continuous aqueous phase and a least one dispersed phase, and which comprises said nucleic acid.
    Type: Application
    Filed: December 1, 2014
    Publication date: June 11, 2015
    Inventors: Jonathan BRUNIAUX, Xavier GIDROL, Fabrice NAVARRO Y GARCIA, Eric SULPICE