Abstract: The present disclosure relates to a Wingless-type (wnt) inhibitor of formula (I) for use in the treatment of fibrosis and some fibrosis mediated disorders such as stiff skin syndrome and systemic sclerosis. The present disclosure also provides a method for the treatment of fibrosis, a pharmaceutical combination comprising a wnt inhibitor of formula (I) and a second active ingredient for use in the treatment of fibrosis and also the use of a wnt inhibitor of formula (I) or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of fibrosis and fibrosis mediated disorders.

Abstract: The invention relates to a mounting device (1, 1?) for mounting a fork, comprising at least one fork blade (2), on a machine bucket (3), wherein the mounting device (1, 1?) comprises at least one pre-tensioned plate (4) arranged on said at least one fork blade (2), and at least one upper tension stop (6) against which said at least one pre-tensioned pressure plate (4) is pre-tensioned for mounting the machine bucket (3) by clamping the bucket (3) between said at least one pre-tensioned plate (4) and said at least one upper tension stop (6). The invention also relates to a mounting method for mounting a fork (2) on a bucket (3).

Abstract: This invention relates to the use of recombinant adeno-associated virus (rAAV) vectors to transduce cardiomyocytes in vivo by infusing the rAAV into a coronary artery or coronary sinus. rAAV infection is not associated with detectable myocardial inflammation or myocyte necrosis. Thus, rAAV is a useful vector for the stable expression of therapeutic genes in the myocardium and can be used to deliver genes for inducing angiogenesis, inhibiting angiogenesis, stimulating cell proliferation, inhibiting cell proliferation and/or treating or ameliorating other cardiovascular conditions.

Abstract: This invention relates to the use of recombinant adeno-associated virus (rAAV) vectors to transduce cardiomyocytes in vivo by infusing the rAAV into a coronary artery or coronary sinus. rAAV infection is not associated with detectable myocardial inflammation or myocyte necrosis. Thus, rAAV is a useful vector for the stable expression of therapeutic genes in the myocardium and can be used to deliver genes for inducing angiogenesis, inhibiting angiogenesis, stimulating cell proliferation, inhibiting cell proliferation and/or treating or ameliorating other cardiovascular conditions.

Abstract: A dust separation apparatus including a cyclone consisting of three sections, a first cylindrical section provided with a tangentially located inlet duct for dust-loaded waste gases, a second cylindrical section therebelow, and below that a third cone-shaped section. According to the invention, a rotor is located in the second section, which rotor carries outside its periphery one or more emission electrodes. A scraping device is provided outside the rotor to scrape accumulated dust from the inner surface of the second section, which surface acts as a precipitation electrode for dust particles charged by the emission electrode or electrodes.

Abstract: A device for transfer of fresh air or air mixed with gases, vapors, smaller particles etc. in one or other direction between a stationary place and a moving place. A stationary elongated box is in communication with the stationary place and has a slot in its longitudinal direction and said slot closeable by a tightening band bearing on contact surfaces at each side of the slot and on the outside of the box. A hollow connection body projects through and is movable along said slot and is in communication with the moving place. Said connection body is provided with slide shoe or shoes in the slot and carries a press roller at each end of the slide shoe or at each slide shoe pressing the band against said contact surfaces and backing rollers lifting the band from engagement with the contact surfaces.