Patents by Inventor Eric T. Ahrens

Eric T. Ahrens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FLUOROCARBON NANOEMULSIONS AND USES THEREOF IN IMAGING
    Publication number: 20230346989
    Abstract: The disclosure relates to compositions comprising (i) at least one fluorocarbon, (ii) at least one fluorous hydroxamic acid chelator, and in some instances, (iii) at least one radioisotope. The disclosure also relates to methods for using such compositions, methods of making such compositions, and kits for making such compositions.
    Type: Application
    Filed: September 17, 2021
    Publication date: November 2, 2023
    Inventors: Eric T. Ahrens, Stephen Adams, Chao Wang, Benjamin Leach
  • CELL PENETRATING PEPTIDE FUNCTIONALIZED PERFLUOROCARBON NANOEMULSION COMPOSITIONS AND METHODS FOR IMAGING CELL POPULATIONS
    Publication number: 20220273824
    Abstract: This disclosure provides compositions of fluorinated nanoemulsions and associated methods for producing cellular labels for tracking cells by magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), and related methods.
    Type: Application
    Filed: August 6, 2020
    Publication date: September 1, 2022
    Inventors: Eric T. Ahrens, Dina Hingorani, Stephen Adams
  • Compositions and methods for imaging cell populations
    Patent number: 11406721
    Abstract: This disclosure provides compositions of metal-binding fluorinated compounds and associated methods for producing cellular labels for tracking cells by magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), and related methods.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: August 9, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Roger Y. Tsien, Eric T. Ahrens, Alexander A. Kislukhin
  • FLUOROUS METAL CHELATES COMPOSITIONS
    Publication number: 20220033424
    Abstract: This disclosure provides compositions of SALTAME core containing compounds and associated methods for use in tracking cells by magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), and related methods.
    Type: Application
    Filed: December 9, 2019
    Publication date: February 3, 2022
    Inventors: Eric T. Ahrens, Stephen Adams, Chao Wang
  • COMPOSITIONS AND METHODS FOR IMAGING CELL POPULATIONS
    Publication number: 20210205479
    Abstract: This disclosure provides compositions of metal-binding fluorinated compounds and associated methods for producing cellular labels for tracking cells by magnetic resonance imaging (MRI), computed tomography (CT), positron emission tomography (PET), and related methods.
    Type: Application
    Filed: February 22, 2017
    Publication date: July 8, 2021
    Inventors: Roger Y. Tsien, Eric T. Ahrens, Alexander A. Kislukhin
  • Magnetic resonance imaging cell labeling methods and compositions
    Patent number: 9649393
    Abstract: The disclosure provides, in part, fluorocarbon imaging reagents and methods for image-guided treatment and/or diagnosis of a subject with a condition associated with an inflammatory response in an internal organ. The disclosure additionally provides methods for image-guided treatment of myocardial infarction (MI) in a subject.
    Type: Grant
    Filed: September 17, 2013
    Date of Patent: May 16, 2017
    Assignees: University of Pittsburgh-of the Commonwealth System of Higher Education, Carnegie Mellon University
    Inventors: Eric T. Ahrens, David Schwartzman
  • Compositions and methods for producing emulsions for nuclear magnetic resonance techniques and other applications
    Patent number: 9352057
    Abstract: The disclosure provides, in part, compositions and methods for producing emulsions. In certain embodiments, emulsions of the disclosure can be used for the detection of inflammation and cell tracking using MRI. The disclosure provides, in part, methods for labeling, detecting and quantifying cell members, in vivo. In certain embodiments, emulsions can be used as an artificial blood substitute.
    Type: Grant
    Filed: May 24, 2013
    Date of Patent: May 31, 2016
    Assignee: Celsense, Inc.
    Inventors: Eric T. Ahrens, Jelena Janjic
  • Magnetic Resonance Imaging Cell Labeling Methods and Compositions
    Publication number: 20140093452
    Abstract: The disclosure provides, in part, fluorocarbon imaging reagents and methods for image-guided treatment and/or diagnosis of a subject with a condition associated with an inflammatory response in an internal organ. The disclosure additionally provides methods for image-guided treatment of myocardial infarction (MI) in a subject.
    Type: Application
    Filed: September 17, 2013
    Publication date: April 3, 2014
    Inventors: Eric T. Ahrens, David Schwartzman
  • COMPOSITIONS AND METHODS FOR PRODUCING EMULSIONS FOR NUCLEAR MAGNETIC RESONANCE TECHNIQUES AND OTHER APPLICATIONS
    Publication number: 20130343999
    Abstract: The disclosure provides, in part, compositions and methods for producing emulsions. In certain embodiments, emulsions of the disclosure can be used for the detection of inflammation and cell tracking using MRI. The disclosure provides, in part, methods for labeling, detecting and quantifying cell members, in vivo. In certain embodiments, emulsions can be used as an artificial blood substrate.
    Type: Application
    Filed: May 24, 2013
    Publication date: December 26, 2013
    Applicant: Celsense, Inc.
    Inventors: Eric T. Ahrens, Jelena Janjic
  • Cellular labeling for nuclear magnetic resonance techniques
    Patent number: 8449866
    Abstract: This disclosure provides, in part, fluorocarbon imaging reagents and formulations for the ex vivo labeling of cells. Labeled cells may be detected in vivo or ex vivo by a nuclear magnetic resonance technique, such as magnetic resonance imaging (MRI) or magnetic resonance spectroscopy (MRS). The disclosure additionally provides methods for using the imaging reagents in a variety of clinical procedures.
    Type: Grant
    Filed: March 6, 2012
    Date of Patent: May 28, 2013
    Assignee: Carnegie Mellon University
    Inventor: Eric T. Ahrens
  • CELLULAR LABELING FOR NUCLEAR MAGNETIC RESONANCE TECHNIQUES
    Publication number: 20130022990
    Abstract: This disclosure provides, in part, fluorocarbon imaging reagents and formulations for the ex vivo labeling of cells. Labeled cells may be detected in vivo or ex vivo by a nuclear magnetic resonance technique, such as magnetic resonance imaging (MRI) or magnetic resonance spectroscopy (MRS). The disclosure additionally provides methods for using the imaging reagents in a variety of clinical procedures.
    Type: Application
    Filed: March 6, 2012
    Publication date: January 24, 2013
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventor: Eric T. Ahrens
  • Cellular labeling and quantification for nuclear magnetic resonance techniques
    Patent number: 8263043
    Abstract: The disclosure provides, in part, a method for quantifying cell numbers in vivo. The disclosure comprises a method of quantifying labeled cells by nuclear magnetic resonance techniques and a computer method for the same.
    Type: Grant
    Filed: April 16, 2007
    Date of Patent: September 11, 2012
    Assignee: Carnegie Mellon University
    Inventors: Eric T. Ahrens, Mangala Srinivas
  • Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques
    Patent number: 8227610
    Abstract: The disclosure provides, in part, compositions of perfluoro polyether compounds and associated methods for producing cellular labels for tracking cells by MRI and methods for labeling, detecting and quantifying cell numbers in vivo.
    Type: Grant
    Filed: July 10, 2008
    Date of Patent: July 24, 2012
    Assignee: Carnegie Mellon University
    Inventors: Jelena Janjic, Eric T. Ahrens
  • Cellular labeling for nuclear magnetic resonance techniques
    Patent number: 8147806
    Abstract: The disclosure provides, in part, fluorocarbon imaging reagents and formulations for the ex vivo labeling of cells. Labeled cells may be detected in vivo or ex vivo by a nuclear magnetic resonance technique, such as magnetic resonance imaging (MRI) or magnetic resonance spectroscopy (MRS). The disclosure additionally provides methods for using the imaging reagents in a variety of clinical procedures.
    Type: Grant
    Filed: January 11, 2005
    Date of Patent: April 3, 2012
    Assignee: Carnegie Mellon University
    Inventor: Eric T. Ahrens
  • METHODS FOR MAGNETIC RESONANCE IMAGING
    Publication number: 20120021450
    Abstract: In certain aspects the present invention provides methods and compositions related to contrast agents for magnetic resonance imaging. In certain variations, contrast agents provided herein are generated in situ via genetic instructions and become potent upon sequestering available metal atoms. Exemplary contrast agents include metal-binding proteins.
    Type: Application
    Filed: July 18, 2011
    Publication date: January 26, 2012
    Applicant: CARNEGIE MELLON UNIVERSITY
    Inventors: Eric T. Ahrens, Clinton S. Robison
  • Methods for magnetic resonance imaging
    Patent number: 7998704
    Abstract: In certain aspects the present invention provides methods and compositions related to contrast agents for magnetic resonance imaging. In certain variations, contrast agents provided herein are generated in situ via genetic instructions and become potent upon sequestering available metal atoms. Exemplary contrast agents include metal-binding proteins.
    Type: Grant
    Filed: March 14, 2005
    Date of Patent: August 16, 2011
    Assignee: Carnegie Mellon University
    Inventors: Eric T. Ahrens, Clinton S. Robison
  • COMPOSITIONS AND METHODS FOR PRODUCING EMULSIONS FOR NUCLEAR MAGNETIC RESONANCE TECHNIQUES AND OTHER APPLICATIONS
    Publication number: 20110110863
    Abstract: The disclosure provides, in part, compositions and methods for producing emulsions. In certain embodiments, emulsions of the disclosure can be used for the detection of inflammation and cell tracking using MRI. The disclosure provides, in part, methods for labeling, detecting and quantifying cell numbers in vivo.
    Type: Application
    Filed: May 1, 2009
    Publication date: May 12, 2011
    Applicant: CELSENSE, INC.
    Inventors: Eric T. Ahrens, Jelena Janjic
  • Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques
    Publication number: 20090074673
    Abstract: The disclosure provides, in part, compositions and methods for producing cellular labels for tracking cells by MRI. The disclosure provides, in part, methods for labeling, detecting and quantifying cell numbers in vivo.
    Type: Application
    Filed: July 10, 2008
    Publication date: March 19, 2009
    Applicant: Carnegie Mellon University
    Inventors: Jelena Janjic, Eric T. Ahrens
  • Cellular Labeling for Nuclear Magnetic Resonance Techniques
    Publication number: 20080292554
    Abstract: The disclosure provides, in part, fluorocarbon imaging reagents and formulations for the ex vivo labeling of cells. Labeled cells may be detected in vivo or ex vivo by a nuclear magnetic resonance technique, such as magnetic resonance imaging (MRI) or magnetic resonance spectroscopy (MRS). The disclosure additionally provides methods for using the imaging reagents in a variety of clinical procedures.
    Type: Application
    Filed: January 11, 2005
    Publication date: November 27, 2008
    Applicant: Carnegie Mellon University
    Inventor: Eric T. Ahrens