Patents by Inventor Eric T. LARSON

Eric T. LARSON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases
    Patent number: 11247972
    Abstract: Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the infectious eukaryotic parasites Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) are described. In particular, the present disclosure is directed to compositions and methods for inhibiting either T. gondii calcium dependent protein kinases (TgCDPKs) or C. parvum and C. hominus calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the formula, wherein the variables X, Y, Z, L, R1, and R3 are defined herein.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: February 15, 2022
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Wesley C. Van Voorhis, Wilhelmus G. J. Hol, Eric T. Larson, Dustin James Maly, Ethan Merritt, Kayode K. Ojo
  • Compositions and Methods for Treating Toxoplasmosis, Cryptosporidiosis, and Other Apicomplexan Protozoan Related Diseases
    Publication number: 20200223803
    Abstract: Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the infectious eukaryotic parasites Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) are described. In particular, the present disclosure is directed to compositions and methods for inhibiting either T. gondii calcium dependent protein kinases (TgCDPKs) or C. parvum and C. hominus calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the formula, wherein the variables X, Y, Z, L, R1, and R3 are defined herein.
    Type: Application
    Filed: January 10, 2020
    Publication date: July 16, 2020
    Inventors: Wesley C. Van Voorhis, Wilhelmus G.J. Hol, Eric T. Larson, Dustin James Maly, Ethan Merritt, Kayode K. Ojo
  • Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases
    Patent number: 10632122
    Abstract: The present disclosure is directed to compositions and methods for inhibiting either Toxoplasma gondii (T. gondii) calcium dependent protein kinases (TgCDPKs) or Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the Formula (I), wherein the variables X, Y, Z, R1, and R3 are defined herein.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: April 28, 2020
    Assignee: University of Washington
    Inventors: Wilhelmus G. J. Hol, Eric T. Larson, Dustin James Maly, Wesley C. Van Voorhis, Ethan Merritt, Kayode K. Ojo
  • Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases
    Patent number: 10544104
    Abstract: Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the infectious eukaryotic parasites Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) are described. In particular, the present disclosure is directed to compositions and methods for inhibiting either T. gondii calcium dependent protein kinases (TgCDPKs) or C. parvum and C. hominus calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the formula, wherein the variables X, Y, Z, L, R1, and R3 are defined herein.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: January 28, 2020
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR CO
    Inventors: Wesley C. Van Voorhis, Wilhelmus G. J. Hol, Eric T. Larson, Dustin James Maly, Ethan Merritt, Kayode K. Ojo
  • Compositions and Methods for Treating Toxoplasmosis, Cryptosporidiosis and Other Apicomplexan Protozoan Related Diseases
    Publication number: 20190358231
    Abstract: The present disclosure is directed to compositions and methods for inhibiting either Toxoplasma gondii (T. gondii) calcium dependent protein kinases (TgCDPKs) or Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the Formula (I), wherein the variables X, Y, Z, R1, and R3 are defined herein.
    Type: Application
    Filed: May 2, 2019
    Publication date: November 28, 2019
    Inventors: Wilhelmus G.J. HOL, Eric T. LARSON, Dustin James MALY, Wesley C. VAN VOORHIS, Ethan MERRITT, Kayode K. OJO
  • Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases
    Patent number: 10307425
    Abstract: The present disclosure is directed to compositions and methods for inhibiting either Toxoplasma gondii (T. gondii) calcium dependent protein kinases (TgCDPKs) or Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-?]pyrazine inhibitors, of the Formula (I), wherein the variables X, Y, Z, R1, and R3 are defined herein.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: June 4, 2019
    Assignee: University of Washington
    Inventors: Wilhelmus G. J. Hol, Eric T. Larson, Dustin James Maly, Wesley C. Van Voorhis, Ethan Merritt, Kayode K. Ojo
  • COMPOSITIONS AND METHODS FOR TREATING TOXOPLASMOSIS, CRYPTOSPORIDIOSIS AND OTHER APICOMPLEXAN PROTOZOAN RELATED DISEASES
    Publication number: 20180273537
    Abstract: The present disclosure is directed to compositions and methods for inhibiting either Toxoplasma gondii (T. gondii) calcium dependent protein kinases (TgCDPKs) or Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the Formula (I), wherein the variables X, Y, Z, R1, and R3 are defined herein.
    Type: Application
    Filed: January 26, 2016
    Publication date: September 27, 2018
    Inventors: Wilhelmus G.J HOL, Eric T. LARSON, Dustin James MALY, Wesley C. VAN VOORHIS, Ethan MERRITT, Kayode K. OJO
  • Compositions and Methods for Treating Toxoplasmosis, Cryptosporidiosis, and Other Apicomplexan Protozoan Related Diseases
    Publication number: 20180022709
    Abstract: Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the infectious eukaryotic parasites Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) are described. In particular, the present disclosure is directed to compositions and methods for inhibiting either T. gondii calcium dependent protein kinases (TgCDPKs) or C. parvum and C. hominus calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the formula, wherein the variables X, Y, Z, L, R1, and R3 are defined herein.
    Type: Application
    Filed: August 25, 2017
    Publication date: January 25, 2018
    Inventors: Wesley C. Van Voorhis, Wilhelmus G.J. Hol, Eric T. Larson, Dustin James Maly, Ethan Merritt, Kayode K. Ojo
  • Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases
    Patent number: 9765037
    Abstract: Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the infectious eukaryotic parasites Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) are described. In particular, the present disclosure is directed to compositions and methods for inhibiting either T. gondii calcium dependent protein kinases (TgCDPKs) or C. parvum and C. hominus calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the formula, wherein the variables X, Y, Z, L, R1, and R3 are defined herein.
    Type: Grant
    Filed: July 30, 2012
    Date of Patent: September 19, 2017
    Assignee: University of Washington Through its Center for Commercialization
    Inventors: Wesley C. Van Voorhis, Wilhelmus G. J. Hol, Eric T. Larson, Dustin James Maly, Ethan Merritt, Kayode K. Ojo
  • METHOD AND SYSTEM FOR ACQUIRING AND ANALYZING MULTIPLE IMAGE DATA LOOPS
    Publication number: 20130253319
    Abstract: A method and system for acquiring and analyzing multiple image data loops comprising: receiving a set of ultrasound data, characterizing a tissue, collected over a first collection loop and a second collection loop; determining a tissue parameter distribution within the tissue based on the set of ultrasound data and multi-dimension speckle tracking; receiving identification of at least one region of interest represented in the set of ultrasound data in the first collection loop and the second collection loop; measuring a comparative characteristic, in the region of interest, between the first collection loop and the second collection loop; and rendering at least one of the comparative characteristic and the tissue parameter distribution. The system comprises a processor, an analysis engine, and a user interface, and may further comprise an ultrasound scanner. The system is preferably configured to perform the method.
    Type: Application
    Filed: March 12, 2013
    Publication date: September 26, 2013
    Applicant: ULTRASOUND MEDICAL DEVICES, INC.
    Inventors: James Hamilton, Eric J. Sieczka, Eric T. Larson
  • Compositions And Methods For Treating Toxoplasmosis, Cryptosporidiosis, And Other Apicomplexan Protozoan Related Diseases
    Publication number: 20130018040
    Abstract: Compositions and methods for the treatment of toxoplasmosis, caused by the infectious eukaryotic parasite Toxoplasma gondii (T. gondii) and for the treatment of cryptosporidiosis, caused by the infectious eukaryotic parasites Cryptosporidium parvum (C. parvum) and Cryptosporidium hominus (C. hominus) are described. In particular, the present disclosure is directed to compositions and methods for inhibiting either T. gondii calcium dependent protein kinases (TgCDPKs) or C. parvum and C. hominus calcium dependent protein kinases (CpCDPKs) using pyrazolopyrimidine and/or imidazo[1,5-a]pyrazine inhibitors, of the formula, wherein the variables X, Y, Z, L, R1, and R3 are defined herein.
    Type: Application
    Filed: July 30, 2012
    Publication date: January 17, 2013
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Wesley C. VAN VOORHIS, Wilhelmus G.J. HOL, Eric T. LARSON, Dustin James MALY, Ethan MERRITT, Kayode K. OJO