Abstract: Implantable electrical connectors employ a conductive circular coil spring contact retained with in a non-conductive housing and a conductive lead attached to the conductive circular coil spring contact. An implantable electrical connector assembly includes a male connector and a female connector. The male connector includes an electrical contact mounted to an elongated electrical contact support member. The female electrical connector includes a connector body and a female contact assembly disposed within the connector body. The female contact assembly includes a conductive circular coil spring, a conductive lead, and a non-conductive housing. The conductive lead is connected to the conductive circular coil spring. The conductive circular coil spring is disposed within and retained by the non-conductive housing. The conductive lead extends from within the non-conductive housing to outside of the non-conductive housing.

Abstract: Blood pump devices having improved rotary seals for sealing a bearing assembly supporting a rotor provided herein. Such rotary seals are particularly suited for use in blood pump devices that include rotors having cantilevered supported through a sealed mechanical bearing disposed outside a blood flow path of the device to avoid thrombus formation caused by blood contact with the bearing. The rotary seal can include a first and second face seal that are preloaded with a deflectable compliance member incorporated into the pump housing or a pair of magnets. Such rotary seals can instead or further utilize tight fitment between components or a bio-absorbable fill material to seal an interface between the rotor shaft and pump housing to seal the bearing assembly from fluid flowing through the pump.

Abstract: A method for making an acellular human amnion-derived composition configured for therapeutic use is disclosed and generally includes the steps: obtaining amniotic membrane tissue; testing the amniotic membrane tissue for pathogens; washing the amniotic membrane tissue; manually removing blood-containing chorion tissue from the amniotic membrane tissue decellularizing the amniotic membrane tissue with xeno-free enzymes; collecting amniotic cells from the decellularized amniotic membrane tissue; seeding the amniotic cells for culture into xeno-free media formulated for mesenchymal stem cells; growing the amniotic cells to a specified confluency; collecting conditioned media; and freezing the collected conditioned media; wherein the method further includes irradiating the conditioned media.

Abstract: Blood pump devices having improved rotary seals for sealing a bearing assembly supporting a rotor provided herein. Such rotary seals are particularly suited for use in blood pump devices that include rotors having cantilevered supported through a sealed mechanical bearing disposed outside a blood flow path of the device to avoid thrombus formation caused by blood contact with the bearing. The rotary seal can include a first and second face seal that are preloaded with a deflectable compliance member incorporated into the pump housing or a pair of magnets. Such rotary seals can instead or further utilize tight fitment between components or a bio-absorbable fill material to seal an interface between the rotor shaft and pump housing to seal the bearing assembly from fluid flowing through the pump.

Abstract: A method for making an acellular human amnion-derived composition configured for therapeutic use is disclosed and generally includes the steps: obtaining amniotic membrane tissue; testing the amniotic membrane tissue for pathogens; washing the amniotic membrane tissue; manually removing blood-containing chorion tissue from the amniotic membrane tissue decellularizing the amniotic membrane tissue with xeno-free enzymes; collecting amniotic cells from the decellularized amniotic membrane tissue; seeding the amniotic cells for culture into xeno-free media formulated for mesenchymal stem cells; growing the amniotic cells to a specified confluency; collecting conditioned media; and freezing the collected conditioned media; wherein the method further includes irradiating the conditioned media.

Abstract: Blood pump devices having improved rotary seals for sealing a bearing assembly supporting a rotor provided herein. Such rotary seals are particularly suited for use in blood pump devices that include rotors having cantilevered supported through a sealed mechanical bearing disposed outside a blood flow path of the device to avoid thrombus formation caused by blood contact with the bearing. The rotary seal can include a first and second face seal that are preloaded with a deflectable compliance member incorporated into the pump housing or a pair of magnets. Such rotary seals can instead or further utilize tight fitment between components or a bio-absorbable fill material to seal an interface between the rotor shaft and pump housing to seal the bearing assembly from fluid flowing through the pump.

Abstract: Blood pump devices having improved rotary seals for sealing a bearing assembly supporting a rotor provided herein. Such rotary seals are particularly suited for use in blood pump devices that include rotors having cantilevered supported through a sealed mechanical bearing disposed outside a blood flow path of the device to avoid thrombus formation caused by blood contact with the bearing. The rotary seal can include a first and second face seal that are preloaded with a deflectable compliance member incorporated into the pump housing or a pair of magnets. Such rotary seals can instead or further utilize tight fitment between components or a bio-absorbable fill material to seal an interface between the rotor shaft and pump housing to seal the bearing assembly from fluid flowing through the pump.

Abstract: Blood pumps for ventricular assist devices employ a hollow rotor to impel blood through the blood pump. A blood pump includes a housing having a housing inlet, a housing outlet, and a housing blood flow channel through which the housing inlet and the housing outlet are in fluid communication. A motor stator is disposed around the housing blood flow channel and operable to generate a rotating magnetic field. A hollow rotor is disposed within the housing blood flow channel and rotated via the rotating magnetic field. The hollow rotor has a rotor circumferential wall enclosing a rotor blood flow channel. The hollow rotor has at least one rotor blade extending inwardly from the rotor circumferential wall. The at least one rotor blade is configured to impel blood through the rotor blood flow channel when the hollow rotor is rotated via the rotating magnetic field.

Abstract: Blood pumps for ventricular assist devices employ a hollow rotor to impel blood through the blood pump. A blood pump includes a housing having a housing inlet, a housing outlet, and a housing blood flow channel through which the housing inlet and the housing outlet are in fluid communication. A motor stator is disposed around the housing blood flow channel and operable to generate a rotating magnetic field. A hollow rotor is disposed within the housing blood flow channel and rotated via the rotating magnetic field. The hollow rotor has a rotor circumferential wall enclosing a rotor blood flow channel. The hollow rotor has at least one rotor blade extending inwardly from the rotor circumferential wall. The at least one rotor blade is configured to impel blood through the rotor blood flow channel when the hollow rotor is rotated via the rotating magnetic field.

Abstract: Featured is an injectable intraocular lens system including an insertion and injection device and an injectable intraocular lens. In its broadest aspects, the injectable intraocular lens is a deflated flexible bag that is disposed within the insertion and injection device prior to insertion into the eye. In use a portion of the insertion and injection device is inserted into the eye and the flexible bag is deployed out from an aperture in the inserted portion into the eye. Following deployment, the insertion and injection device injects an optical medium, such as a liquid, into the interior of the flexible bag, thereby inflating the bag. In an illustrative embodiment, the amount of medium being injected is selected so that the inflated bag provides the desired corrective power to the intraocular lens so formed.

Abstract: A microsurgical laser probe is provided with a distal end portion of an optic fiber that projects from a tubular sleeve of the probe and can be caused to bend relative to the probe sleeve by manual manipulation of a mechanism on a handle of the probe.

Abstract: Featured is an injectable intraocular lens system including an insertion and injection device and an injectable intraocular lens. In its broadest aspects, the injectable intraocular lens is a deflated flexible bag that is disposed within the insertion and injection device prior to insertion into the eye. In use a portion of the insertion and injection device is inserted into the eye and the flexible bag is deployed out from an aperture in the inserted portion into the eye. Following deployment, the insertion and injection device injects an optical medium, such as a liquid, into the interior of the flexible bag, thereby inflating the bag. In an illustrative embodiment, the amount of medium being injected is selected so that the inflated bag provides the desired corrective power to the intraocular lens so formed.