Patents by Inventor Eric Therrien

Eric Therrien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080280925
    Abstract: The present invention relates to compounds that are useful as inhibitors of protein arginine methyltransferase that have a formula selected from Formula (I), Formula (II) and Formula (III), as well as racemic mixtures, diastereomers, enantiomers and tautomers thereof and N-oxides, hydrates, solvates, pharmaceutically acceptable salts, prodrugs and complexes thereof as defined herein. Said compound are useful as inhibitors of PRMTs and/or CARM-I. The invention further relates to compositions comprising such compounds and methods for their use.
    Type: Application
    Filed: February 28, 2008
    Publication date: November 13, 2008
    Inventors: Amal Wahhab, Eric Therrien, Martin Allan, Sukhdev Manku
  • Publication number: 20070293530
    Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I), and racemic and scalemic mixtures, diastereomers and enantiomers thereof: or an N-oxide, hydrate, solvate, pharmaceutically acceptable salt, prodrug or complex thereof, wherein Y, L, Z, W, M, Ra, Rb and Rc are as defined in the specification.
    Type: Application
    Filed: June 14, 2007
    Publication date: December 20, 2007
    Applicant: METHYLGENE INC.
    Inventors: David Smil, Silvana Leit, Alain Ajamian, Martin Allan, Yves Chantigny, Robert Deziel, Eric Therrien, Amal Wahhab, Sukhdev Manku
  • Publication number: 20070161643
    Abstract: There is provided a compound of formula I wherein the dashed line, R1, R2, R3a, R3b, A, D, E, G and L have meanings given in the description, which compounds are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like proteases, such as thrombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is beneficial (e.g. conditions, such as thrombo-embolisms, where inhibition of thrombin is required or desired, and/or conditions where anticoagulant therapy is indicated).
    Type: Application
    Filed: February 2, 2005
    Publication date: July 12, 2007
    Inventors: Malken Bayrakdarian, Kristina Berggren, Ojvind Davidsson, Ola Fjellstrom, David Gustafsson, Stephen Hanessian, Tord Inghardt, Ingemar Nilsson, Mats Nagard, Daniel Simard, Eric Therrien
  • Publication number: 20070099962
    Abstract: There is provided a compound of formula (I) wherein R1, R2a, R2b, R3a, R3b, R4, R5, R6, A, G and L have meanings given in the description, which compounds are useful as, or are useful as prodrugs of, competitive inhibitors of trypsin-like proteases, such as trombin, and thus, in particular, in the treatment of conditions where inhibition of thrombin is beneficial (e.g. conditions, such as thrombo-embolisms, where inhibition of trombin is required or desired, and/or conditions whereas anticoagulant therapy is indicated).
    Type: Application
    Filed: December 15, 2004
    Publication date: May 3, 2007
    Inventors: Kristina Berggren, Ojvind Davidsson, Ola Fjellstrom, David Gustafsson, Stephen Hanessian, Tord Inghardt, Mats Nagard, Ingemar Nilsson, Eric Therrien, Willem Van Otterlo
  • Publication number: 20060264415
    Abstract: This invention relates to compounds for the inhibition of histone deacetylase. More particularly, the invention provides for compounds of formula (I) wherein Y, L, Z, W, X, Q, R1, R2 and R3 are as defined in the specification.
    Type: Application
    Filed: March 31, 2006
    Publication date: November 23, 2006
    Inventors: Silvana Leit de Moradei, Pierre Tessier, David Smil, Amal Wahhab, Robert Deziel, Sukhdev Manku, John Mancuso, Eric Therrien, Martin Allan, Yves Chantigny, Alain Ajamian, Patrick Beaulieu
  • Patent number: D497441
    Type: Grant
    Filed: June 2, 2003
    Date of Patent: October 19, 2004
    Inventors: Francis Therrien, Eric Therrien