Patents by Inventor Eric Thorin

Eric Thorin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition comprising inhibitors of IRS-1 and of VEGF
    Patent number: 9682144
    Abstract: The present invention relates to a composition or kit of parts comprising an inhibitor of IRS-1 and an inhibitor of the VEGF pathway and to the use thereof for treating an angiogenic disease.
    Type: Grant
    Filed: June 29, 2012
    Date of Patent: June 20, 2017
    Assignee: GENE SIGNAL INTERNATIONAL, SA
    Inventors: Eric Thorin, Salman Al-Mahmood, Sylvie Colin, Antoine Ferry, Eric Viaud
  • Composition Comprising Inhibitors of IRS-1 and of VEGF
    Publication number: 20140134185
    Abstract: The present invention relates to a composition or kit of parts comprising an inhibitor of IRS-1 and an inhibitor of the VEGF pathway and to the use thereof for treating an angiogenic disease.
    Type: Application
    Filed: June 29, 2012
    Publication date: May 15, 2014
    Applicant: GENE SIGNAL INTERNATIONAL SA
    Inventors: Eric Thorin, Salman Al-Mahmood, Sylvie Colin, Antoine Ferry, Eric Viaud
  • COMPOSITION COMPRISING INHIBITORS OF IRS-1 AND OF VEGF
    Publication number: 20130004511
    Abstract: Compositions comprising an inhibitor of IRS-1 and an inhibitor of the VEGF pathway, which compositions rare useful for treating an angiogenic disease. The specification also relates to kits comprising an inhibitor of IRS-1 and an inhibitor of the VEGF pathway, as well as methods of treating angiogenic diseases using such compositions and/or kits.
    Type: Application
    Filed: June 30, 2011
    Publication date: January 3, 2013
    Applicant: GENE SIGNAL INTERNATIONAL SA
    Inventors: Eric Thorin, Salman Al-Mahmood, Sylvie Colin, Antoine Ferry, Éric Viaud
  • Use of ivabradine for obtaining medicaments intended for the treatment of endothelial dysfunction
    Publication number: 20110288072
    Abstract: Use of ivabradine, or 3-{3-[{[(7S)-3,4-dimethoxybicyclo [4.2.0]octa-1,3,5-trien-7-yl]-methyl }-(methyl)-amino]-propyl}-7,8-dimethoxy-1,3,4,5 -tetrahydro-2H-3-benzazepin-2-one, its addition salts with a pharmaceutically acceptable acid and their hydrates, for obtaining a medicament intended for the treatment of endothelial dysfunction.
    Type: Application
    Filed: July 21, 2011
    Publication date: November 24, 2011
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Vidal Benatar, Guy Lerebours-Pigeonniere, Jean-Claude Tardif, Eric Thorin, Eric Rheaume
  • Angiopoietin-like 2 as a biomarker of vascular endothelial cell abnormal function and senescence
    Patent number: 7972795
    Abstract: A method for assessing a physiological state of a mammal. The method includes: obtaining from the mammal a biological sample; measuring the expression of angiopoietin-like 2 in the biological sample; and assessing the physiological state of the mammal by comparing the measured expression of the angiopoietin-like 2 to a predetermined normal expression level in normal subjects, wherein an increase in angiopoietin-like 2 level over the predetermined normal expression level indicates an abnormal physiological state.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: July 5, 2011
    Assignee: Institut de Cardiologie de Montreal
    Inventors: Eric Thorin, Nada Farhat, Nathalie Trescases
  • Use of ivabradine for obtaining medicaments intended for the treatment of endothelial dysfunction
    Publication number: 20080200450
    Abstract: Use of ivabradine, or 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]-methyl}-(methyl)-amino]-propyl}-7,8-dimethoxy-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one, its addition salts with a pharmaceutically acceptable acid and their hydrates, for obtaining a medicament intended for the treatment of endothelial dysfunction.
    Type: Application
    Filed: January 11, 2008
    Publication date: August 21, 2008
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Vidal Benatar, Guy Lerebours-Pigeonniere, Jean-Claude Tardif, Eric Thorin, Eric Rheaume
  • Angiopoietin-like 2 as a biomarker of vascular endothelial cell abnormal function and senescence
    Publication number: 20080166717
    Abstract: A method for assessing a physiological state of a mammal. The method includes: obtaining from the mammal a biological sample; measuring the expression of angiopoietin-like 2 in the biological sample; and assessing the physiological state of the mammal by comparing the measured expression of the angiopoietin-like 2 to a predetermined normal expression level in normal subjects, wherein an increase in angiopoietin-like 2 level over the predetermined normal expression level indicates an abnormal physiological state.
    Type: Application
    Filed: June 20, 2007
    Publication date: July 10, 2008
    Inventor: Eric Thorin