Patents by Inventor Eric Wehrenberg-Klee

Eric Wehrenberg-Klee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Granzyme B Directed Imaging and Therapy
    Publication number: 20230338588
    Abstract: Provided herein are compounds useful for imaging granzyme B. An exemplary compound provided herein is useful as a radiotracer for position emission tomography (PET) and/or single photon emission tomography (SPECT) imaging. Methods of imaging granzyme B, combination therapies, and kits comprising the granzyme B imaging agents are also provided.
    Type: Application
    Filed: January 5, 2023
    Publication date: October 26, 2023
    Inventors: Umar Mahmood, Benjamin Larimer, Eric Wehrenberg-Klee
  • Granzyme B directed imaging and therapy
    Patent number: 11559590
    Abstract: Provided herein are compounds useful for imaging granzyme B. An exemplary compound provided herein is useful as a radiotracer for position emission tomography (PET) and/or single photon emission tomography (SPECT) imaging. Methods of imaging granzyme B, combination therapies, and kits comprising the granzyme B imaging agents are also provided.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: January 24, 2023
    Assignee: The General Hospital Corporation
    Inventors: Umar Mahmood, Benjamin Larimer, Eric Wehrenberg-Klee
  • Granzyme B Directed Imaging and Therapy
    Publication number: 20190224348
    Abstract: Provided herein are compounds useful for imaging granzyme B. An exemplary compound provided herein is useful as a radiotracer for position emission tomography (PET) and/or single photon emission tomography (SPECT) imaging. Methods of imaging granzyme B, combination therapies, and kits comprising the granzyme B imaging agents are also provided.
    Type: Application
    Filed: June 30, 2017
    Publication date: July 25, 2019
    Inventors: Umar Mahmood, Benjamin Larimer, Eric Wehrenberg-Klee
  • Pulmonary malarial vaccine
    Publication number: 20050265928
    Abstract: Particulate compositions for delivery, preferably pulmonary, which provide sustained release of antigens, preferably DNA and/or peptide and/or protein antigens, have been developed. In the preferred embodiment, aggregate nanoparticles are in the aerodynamic range of 1-5 microns diameter and fly deep into the lungs. As the aggregate particles degrade in the body, MSP-1 and AMA-1 proteins are released into the blood stimulating a humoural immune response. The individual particles in the range of 0.1 micron are preferentially phagocytosed by APCs which express the proteins encoded by AMA-1 and MSP-1 plasmid DNA thereby initiating the cellular immune response that is necessary for a complete immunity.
    Type: Application
    Filed: May 9, 2005
    Publication date: December 1, 2005
    Inventors: David Edwards, Jean Sung, Brian Pulliam, Eric Wehrenberg-Klee, Evan Schwartz, Philip Dreyfuss, Sandeep Kulkarni, Erez Lieberman