Patents by Inventor Eric Witze

Eric Witze has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assays based on BTF3 activity
    Publication number: 20060199781
    Abstract: This invention pertains to the discovery that BTF3 plays a critical, negative-regulatory role in programmed cell death (PCD) in C. elegans and other species. Overexpression of BTF3 leads to decreased programmed cell death, while inactivation of BTF3 leads to increased programmed cell death. Methods of modulating (upregulating or downregulating) programmed cell death by increasing or decreasing expression and/or activity of BTF3 are provided. These methods are useful in the treatment of various pathologies including, but not limited to cancer and neurodegenerative diseases.
    Type: Application
    Filed: December 16, 2005
    Publication date: September 7, 2006
    Inventors: Joel Rothman, Tim Bloss, Eric Witze
  • BTF3: an inhibitor of apoptosis
    Publication number: 20030004124
    Abstract: This invention pertains to the discovery that BTF3 plays a critical, negative-regulatory role in programmed cell death (PCD) in C. elegans and other species. Overexpression of BTF3 leads to decreased programmed cell death, while inactivation of BTF3 leads to increased programmed cell death. Methods of modulating (upregulating or downregulating) programmed cell death by increasing or decreasing expression and/or activity of BTF3 are provided. These methods are useful in the treatment of various pathologies including, but not limited to cancer and neurodegenerative diseases.
    Type: Application
    Filed: May 21, 2002
    Publication date: January 2, 2003
    Applicant: The Regents of the University of California
    Inventors: Joel H. Rothman, Tim Bloss, Eric Witze