Abstract: An alternating vacuum and pressure system for decellularizing a bone matrix includes piping having a first end open to atmospheric pressure and a second end open to atmospheric pressure, and a subset of piping that forms a loop, a chamber in fluid, at least one heating element configured to heat the piping, a pump, and a plurality of valves. The plurality of valves can be selectively opened or closed to form one of a plurality of configurations, including a pressure configuration in which operation of the pump in a first direction causes a fluid within the piping to travel toward the chamber such that pressure is applied to the chamber and a vacuum configuration in which operation of the pump in a second direction causes the fluid within the pipe to travel away from the chamber such that a vacuum is created on the chamber.

Abstract: Drilling devices, systems, kits and methods for drilling cartilage defects are disclosed. A system includes a handle device having an adjustable shaft collar rotatable to adjust a drill set distance between the adjustable shaft collar and the handle. The handle device can include a distal drill guide extending from the handle at an end opposite the adjustable shaft collar. The system includes a drill collar attachable to a drill bit and configured to remain stationary along a length of the drill bit once attached. The system includes a rotatable disk positionable between the adjustable shaft collar and the drill collar. The rotatable disk can include a central hole sized to accept the drill bit.

Abstract: Compositions comprising a condensed mesenchymal cell body and a hydrogel are provided. The compositions may further include drugs or growth factors. The condensed mesenchymal cell body may include a connective tissue cell, or even a progenitor cell capable of producing connective tissue extracellular matrices such collagen and glycosaminoglycan. Also provided are methods of treating connective tissue defects, cartilage injury, and cartilage degradation.

Abstract: A graft holder for securely transporting a graft, the graft holder including a base surface; and a cavity extended from the base surface and formed from one or more walls, the cavity configured so the graft is securely nested therewith when being transported between locations so as to minimize damage and/or impact to the graft during transport.

Abstract: A drape management assembly for a robotic surgical system includes a base portion and a grasping portion. The base portion is configured for connection to the robotic surgical system. The grasping portion extends from the base portion and defines a cavity therebetween. The cavity is configured to locate an excess portion of a drape which sheaths at least a robotic arm of the robotic surgical system.

Abstract: A method of placing a surgical robotic cart assembly includes, determining a first position of a first surgical robotic cart assembly relative to a surgical table, calculating a path for the first surgical robotic cart assembly towards a second position of the first surgical robotic cart assembly relative to the surgical table, wherein in the second position, the first surgical robotic cart assembly is spaced-apart a first safe distance from the surgical table, moving the first surgical robotic cart assembly autonomously towards the second position thereof, and detecting a potential collision along the path of the first surgical robotic cart assembly as the first surgical robotic cart assembly moves towards the second position thereof.

Abstract: Compositions comprising a condensed mesenchymal cell body and a hydrogel are provided. The compositions may further include drugs or growth factors. The condensed mesenchymal cell body may include a connective tissue cell, or even a progenitor cell capable of producing connective tissue extracellular matrices such collagen and glycosaminoglycan. Also provided are methods of treating connective tissue defects, cartilage injury, and cartilage degradation.

Abstract: A drape management assembly for a robotic surgical system includes a base portion and a grasping portion. The base portion is configured for connection to the robotic surgical system. The grasping portion extends from the base portion and defines a cavity therebetween. The cavity is configured to locate an excess portion of a drape which sheaths at least a robotic arm of the robotic surgical system.

Abstract: A drape management assembly for a robotic surgical system includes a base portion and a grasping portion. The base portion is configured for connection to the robotic surgical system. The grasping portion extends from the base portion and defines a cavity therebetween. The cavity is configured to locate an excess portion of a drape which sheaths at least a robotic arm of the robotic surgical system.

Abstract: A drape management assembly for a robotic surgical system includes a base portion and a grasping portion. The base portion is configured for connection to the robotic surgical system. The grasping portion extends from the base portion and defines a cavity therebetween. The cavity is configured to locate an excess portion of a drape which sheaths at least a robotic arm of the robotic surgical system.

Abstract: A compression garment includes a bladder having an inner surface and an outer surface. Wicking material may be present to wick fluid. In another version a removable absorbent material is releasably secured to the bladder.

Abstract: A hand-mounted, video-guided system comprising: an element for mounting to at least one finger of a user; a video input carried by said element; an irrigation line carried by said element; a fenestrated suction head for mounting to the hand of a user, said fenestrated suction head comprising a hollow body having fenestrations formed therein, and a suction line having a fenestrated distal end disposed within the interior of said hollow body.

Abstract: The present invention also features a brachytherapy system comprising a spiral cut tube having a first end and a second end; a radioactive brachytherapy source (RBS) disposed on the first end of the spiral cut tube; and a handle and a generally hollow cannula disposed on the handle, wherein a channel is disposed in the handle aligned with the hollow cannula, and the spiral cut tube and RBS are adapted to slide within the channel and the hollow cannula.

Abstract: Described herein are compounds which have the general formula: ##STR1## or a prodrug or pharmaceutically acceptable salt, solvate or hydrate thereof wherein:R.sup.1 is selected from the group consisting of H, alkyl and the counter ion for a basic addition salt;X is selected from the group consisting of CR.sup.9 R.sup.10, S, O, SO, SO.sub.2, NH and N-alkyl;R.sup.2, R.sup.3, R.sup.4, R.sup.9 and R.sup.10 are independently selected from the group consisting of H and alkyl;R.sup.5 and R.sup.6 are independently selected from the group consisting of H, alkyl and phenyl, or, alternatively, R.sup.5 and R.sup.6 together may form a methylene group or a 3- to 6-membered a spirocyclic group;wherein, when X is CR.sup.9 R.sup.10, one or both pairs of R.sup.5 and R.sup.9 or R.sup.6 and R.sup.10 may join to form a double or triple bondR.sup.7 is selected from the group consisting of Formula II-V: ##STR2## which are all optionally substituted, at nodes other than R.sup.

Abstract: Described herein are compounds having the general formula: ##STR1## Ar.sub.1 and Ar.sub.2 are independently selected aryl groups, optionally substituted with substituents selected from the group consisting of alkyl, cycloalkyl, alkoxy, alkanoyl, aralkyl, aralkyloxy, halo, NO.sub.2, Ph, CF.sub.3, CN, OH, methylenedioxy, ethylenedioxy, SO.sub.2 NRR', NRR', CO.sub.2 R (where R and R' are independently selected from the group consisting of H and alkyl) and a second aryl group, which may be substituted as above;wherein any cycloalkyl or aryl substituent is linked to Ar.sub.1 or Ar.sub.2 by a bridging element which may be a single bond, a vinylene group, an ethynylene group, a Z group, a --Z--(CH.sub.2).sub.n -- group, a --(CH.sub.2).sub.n --Z-- group, or a --Z--(CH.sub.2).sub.n --Z-- group, where Z represents an O atom, a S atom, an NH group or an N-alkyl group, and n is an integer from 1 to 4;wherein Ar.sub.1 and Ar.sub.