Abstract: An optical therapy device for providing therapeutic light to a person's nasal cavity includes a body and at least one UV light source in or on the body. A distal end of the body is configured to be inserted into the person's nasal cavity. The body can be configured to be hand-held. The optical therapy device is configured such that the UV light source emits a dose of UV light toward tissue in the patient's nasal cavity.

Abstract: An optical therapy device is disclosed. The optical therapy device provides therapeutic light therapy to a body cavity. The device includes a housing adapted to be hand held, a UV light source positioned in or on the housing, and an insertion member having a distal end configured to be inserted into the body cavity to illuminate tissue in the body cavity with light from the light source.

Abstract: The invention is directed to therapy devices for providing therapeutic light to a target region of tissue within a nasal cavity. The devices are adapted to include a light source communicating with a distal end of the first insertion member, wherein light from the light source illuminates a target region of tissue within a nasal cavity posterior to a limen nasi of the nasal cavity, and further wherein the insertion member is configured to prevent illumination of a region of tissue anterior to the limen nasi. The devices are further adapted to be positioned within the nasal cavity by a user without observing the location of the distal tip.

Abstract: A method and apparatus is described for treating a target body surface using a radiation applicator. The therapeutic treatment apparatus adapted to conform to a patients body. The treatment apparatus comprises a plurality of light sources coupled with a flexible substrate, a light integrator in at least a portion of the optical path between the light source and the patient's body surface, a power supply, and a controller.

Abstract: An optical therapy device for providing therapeutic light to a person's nasal cavity includes a body and at least one UV light source in or on the body. A distal end of the body is configured to be inserted into the person's nasal cavity. The body can be configured to be hand-held. The optical therapy device is configured such that the UV light source emits a dose of UV light toward tissue in the patient's nasal cavity.

Abstract: A method and apparatus is described for treating a target body surface using a radiation applicator. The radiation applicator includes a radiation source in combination with a delivery applicator. The applicator has a low profile enable the patient to apply the applicator to a target area underneath, for example, clothing. The applicator can be configured to use one or more radiation sources to apply one or more types of radiation for one or more periods of time. Additionally, the applicator can be configured with a feedback loop to determine when a therapeutically desirable amount of radiation has been delivered.

Abstract: A method and apparatus is described for treating a target body surface using a radiation applicator. The radiation applicator includes a radiation source in combination with a delivery applicator. The applicator has a low profile enable the patient to apply the applicator to a target area underneath, for example, clothing. The applicator can be configured to use one or more radiation sources to apply one or more types of radiation for one or more periods of time. Additionally, the applicator can be configured with a feedback loop to determine when a therapeutically desirable amount of radiation has been delivered.

Abstract: An optical therapy device is disclosed. The optical therapy device provides therapeutic light therapy to a body cavity. The device includes a housing adapted to be hand held, a UV light source positioned in or on the housing, and an insertion member having a distal end configured to be inserted into the body cavity to illuminate tissue in the body cavity with light from the light source.

Abstract: There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.

Abstract: An optical therapy device for providing therapeutic light to a person's nasal cavity includes a body and at least one UV light source in or on the body. A distal end of the body is configured to be inserted into the person's nasal cavity. The body can be configured to be hand-held. The optical therapy device is configured such that the UV light source emits a dose of UV light toward tissue in the patient's nasal cavity.

Abstract: This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices. In one particular embodiment, methods for enhancing cellular functions on a surface of a medical device implant are disclosed which generally comprise providing a medical device implant comprising a plurality of nanofibers (e.g., nanowires) thereon and exposing the medical device implant to cells such as osteoblasts.

Abstract: There is disclosed an accommodating intraocular lens for implantation in an eye having an optical axis. The lens comprises an anterior portion which in turn comprises an anterior viewing element and an anterior biasing element. The lens further comprises a posterior portion which in turn comprises a posterior viewing element in spaced relationship to the anterior viewing element and a posterior biasing element. The anterior portion and posterior portion meet at first and second apices of the intraocular lens. The anterior portion and the posterior portion and/or the apices are responsive to force thereon to cause the separation between the viewing elements to change. Additional embodiments and methods are also disclosed.

Abstract: This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices.