Patents by Inventor Erica Stahle

Erica Stahle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120115865
    Abstract: The present invention relates to new pharmaceutically acceptable salts of 2-hydroxy-3-[5-(morpholin-4-yl-methyl)pyridin-2-yl]1H-indole-5-carbonitrile, processes for their preparations, pharmaceutical formulations containing said salts and to the use of said active salts in therapy, and particularly to GSK3 related disorders.
    Type: Application
    Filed: January 31, 2007
    Publication date: May 10, 2012
    Inventors: Anna-Lena Berg, Ratan Bhat, Tesfai Sebhatu, Erica Stahle
  • Patent number: 8008294
    Abstract: The salt, the 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile citrate, a process for its preparation, pharmaceutical formulations containing it and the use of it in therapy, and particularly in the therapy of GSK3 related conditions and disorders.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: August 30, 2011
    Assignee: AstraZeneca AB
    Inventors: Tesfai Sebhatu, Erica Ståhle
  • Publication number: 20090023732
    Abstract: The salt, the 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile citrate, a process for its preparation, pharmaceutical formulations containing it and the use of it in therapy, and particularly in the therapy of GSK3 related conditions and disorders.
    Type: Application
    Filed: January 31, 2007
    Publication date: January 22, 2009
    Applicant: AstraZeneca AB
    Inventors: Anna-Lena Berg, Ratan Bhat, Tesfai Sebhatu, Erica Stahle
  • Publication number: 20070203137
    Abstract: The present invention relates to a new pharmaceutically acceptable salt, the 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile citrate, a process for its preparation, pharmaceutical formulations containing said salt and to the use of said active salt in therapy, and particularly to GSK3 related conditions and disorders.
    Type: Application
    Filed: February 2, 2007
    Publication date: August 30, 2007
    Applicant: ASTRAZENECA AB
    Inventors: Tesfai Sebhatu, Erica Stahle
  • Publication number: 20060194879
    Abstract: A calcium or a magnesium salt of (2S)-2-ethoxy-3-(4-{2[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid.
    Type: Application
    Filed: June 16, 2004
    Publication date: August 31, 2006
    Applicant: AstraZeneca AB
    Inventors: Ralf Ragnar, Erica Stahle
  • Publication number: 20060142389
    Abstract: A compound selected from one or more of the following: a (1R,2S)-2-hydroxyindan-1-amine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; an L-arginine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino-2-oxoethoxyphenyl)propanoic acid; a tert-butylamine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino-2-oxoethoxyphenyl)propanoic acid; a choline salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; an adamantylamine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; a N-benzyl-2-phenylethanaminium salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; a N-benzyl-2-(benzylamino) ethanaminium salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid; or a tris(hydroxymethyl)methylamine salt of (2S)-2-ethoxy-3-(4-{2-[hexyl(2-phenylethyl)amino]-2-oxoethoxy}phenyl)propanoic acid.
    Type: Application
    Filed: June 16, 2004
    Publication date: June 29, 2006
    Applicant: AstraZeneca AB
    Inventors: Carl-Johan Aurell, Mikael Dahlstrom, Eva-Lotte Lindstedt-Alstermark, Anna Minidis, Bengt Ohlsson, Erica Stahle
  • Patent number: 6706710
    Abstract: This invention relates to a novel form of a scrotonin h5-HT1B-receptor antagonist, namely a novel form of a salt of (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,2,4-tetrahydro-2-naphtyl]-4-morpholinobenzamide referred to as (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphtyl]-4-morpholinobenzamide monohydrobromide Form A. The invention also relates to processes for preparation of said of Form A, which form has a potential use after suitable pharmaceutical formulation in medical treatment, preferably in CNS disorders, over active bladder or vasospam, or growth control of tumors.
    Type: Grant
    Filed: January 17, 2003
    Date of Patent: March 16, 2004
    Assignee: AstraZeneca AB
    Inventors: Per-Olov Bergström, Martin Hedberg, Mona Lindström, Erica Ståhle
  • Publication number: 20030166653
    Abstract: This invention relates to a novel form of a serotonin h5-HT1B-receptor antagonist, namely a novel form of a salt of (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphtyl]-4-morpholinobenzamide referred to as (R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphtyl]-4-morpholinobenzamide monohydrobromide Form A. The invention also relates to processes for preparation of said of Form A, which form has a potential use after suitable pharmaceutical formulation in medical treatment, preferably in CNS disorders, over active bladder or vasospam, or growth control of tumors.
    Type: Application
    Filed: January 17, 2003
    Publication date: September 4, 2003
    Inventors: Per-Olov Bergstrom, Martin Hedberg, Mona Lindstrom, Erica Stahle