Patents by Inventor Erich Grotewold

Erich Grotewold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7592506
    Abstract: Methods for altering levels in plants of one or more phenolic compounds that are intermediates or final products of the plant phenylpropanoid pathway are provided. One method comprises transforming a plant cell with an expression construct comprising a nucleic acid which encodes a transactivator protein comprising the myb domain of the maize “ZmMyb-IF35” protein and an activation domain. Another method comprises transforming a plant cell with an expression construct comprising a transgene which encodes an antisense ZmMyb-IF35 RNA. The present invention also relates to expression constructs and vectors used in the present methods, transformed plant cells and transgenic plants prepared according to the present methods, and the seeds of such transgenic plants.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: September 22, 2009
    Assignee: The Ohio State University Research Foundation
    Inventors: Erich Grotewold, Anusha P Dia, Edward L. Braun
  • Publication number: 20080235829
    Abstract: Methods for altering levels in plants of one or more phenolic compounds that are intermediates or final products of the plant phenylpropanoid pathway are provided. One method comprises transforming a plant cell with an expression construct comprising a nucleic acid which encodes a transactivator protein comprising the myb domain of the maize “ZmMyb-IF35” protein and an activation domain. Another method comprises transforming a plant cell with an expression construct comprising a transgene which encodes an antisense ZmMyb-IF35 RNA. The present invention also relates to expression constructs and vectors used in the present methods, transformed plant cells and transgenic plants prepared according to the present methods, and the seeds of such transgenic plants.
    Type: Application
    Filed: December 22, 2006
    Publication date: September 25, 2008
    Applicant: The Ohio State University Research Foundation
    Inventors: Erich Grotewold, Anusha P. Dias, Edward L. Braun
  • Publication number: 20080200538
    Abstract: Methods comprising administering to the subject apigenin, an apigenin derivative, apigenin and at least one apigenin derivative, or a combination of apigenin derivatives are provided for treating inflammation in a subject in need of the same.
    Type: Application
    Filed: May 26, 2006
    Publication date: August 21, 2008
    Inventors: Andrea Doseff, Erich Grotewold
  • Patent number: 7154023
    Abstract: Methods for altering levels in plants of one or more phenolic compounds that are intermediates or final products of the plant phenylpropanoid pathway are provided. One method comprises transforming a plant cell with an expression construct comprising a nucleic acid which encodes a transactivator protein comprising the myb domain of the maize “ZmMyb-IF35” protein and an activation domain. Another method comprises transforming a plant cell with an expression construct comprising a transgene which encodes an antisense ZmMyb-IF35 RNA. The present invention also relates to expression constructs and vectors used in the present methods. transformed plant cells and transgenic plants prepared according to the present methods, and the seeds of such transgenic plants.
    Type: Grant
    Filed: March 8, 2002
    Date of Patent: December 26, 2006
    Assignee: The Ohio State University Research Foundation
    Inventors: Erich Grotewold, Anusha P. Dias, Edward L. Braun
  • Patent number: 6709867
    Abstract: Transgenic grass plants which exhibit a color different from the color exhibited by the corresponding non-transgenic grass plants under conditions of stress are provided Examples of such conditions include, but are not limited to, lack of fertilizer, lack of water, and attack by insects or pathogens. The genome of the transgenic grass plant comprises a transgene comprising a nucleic acid which encodes one or more regulators of anthocyanin biosynthesis, and an inducible promoter which is responsive to a stress condition, such as for example, nutrient deprivation, water deprivation, and attack by a pathogen.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: March 23, 2004
    Assignee: The Ohio State University Research Foundation
    Inventor: Erich Grotewold
  • Publication number: 20030150011
    Abstract: Methods for altering levels in plants of one or more phenolic compounds that are intermediates or final products of the plant phenylpropanoid pathway are provided. One method comprises transforming a plant cell with an expression construct comprising a nucleic acid which encodes a transactivator protein comprising the myb domain of the maize “ZmMyb-IF35” protein and an activation domain. Another method comprises transforming a plant cell with an expression construct comprising a transgene which encodes an antisense ZmMyb-IF35 RNA. The present invention also relates to expression constructs and vectors used in the present methods. transformed plant cells and transgenic plants prepared according to the present methods, and the seeds of such transgenic plants.
    Type: Application
    Filed: March 8, 2002
    Publication date: August 7, 2003
    Inventors: Erich Grotewold, Anusha P. Dias, Edward L. Braun
  • Publication number: 20020188964
    Abstract: Transgenic grass plants which exhibit a color different from the color exhibited by the corresponding non-transgenic grass plants under conditions of stress are provided Examples of such conditions include, but are not limited to, lack of fertilizer, lack of water, and attack by insects or pathogens. The genome of the transgenic grass plant comprises a transgene comprising a nucleic acid which encodes one or more regulators of anthocyanin biosynthesis, and an inducible promoter which is responsive to a stress condition, such as for example, nutrient deprivation, water deprivation, and attack by a pathogen. Transgenic grass plants which constitutively exhibits a different color phenotype, particularly a red color phenotype, are also provided. The genome the transgenic grass plant comprises a transgene comprising an exogenous anthocyanin regulatory gene operably linked to a constitutive promoter. Grass plants that constitutively display a colored phenotype are useful for display and decorative purposes.
    Type: Application
    Filed: October 26, 2001
    Publication date: December 12, 2002
    Inventor: Erich Grotewold