Patents by Inventor Erich Hochuli

Erich Hochuli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing alpha-interferon
    Patent number: 6005075
    Abstract: The invention provides processes for producing Alpha-Interferon (IFN-.alpha.) free from possible mouse and/or virus contamination. The present invention further provides homogeneous IFN-.alpha. free from mouse and/or virus contamination and its use in antitumor and/or antiviral treatment.
    Type: Grant
    Filed: July 23, 1997
    Date of Patent: December 21, 1999
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Urs Ettlin, Erich Hochuli, Alfred Schacher, Karl Weyer
  • Tocopherol cyclase isolated from Chlorella protothecoides, Dunaliella salina and wheat leaves
    Patent number: 5432069
    Abstract: A tocopherol cyclase is produced in homogenous form which acts on phytyl benzoquinol derivatives to produce R', R', R'-tocopherols enantioselectively. The cyclase has a molecular weight of from about 48 kD to about 50 kD as determined by SDS-PAGE. The cyclase is isolated from Chlorella protothecoides, Dunaliella salina and wheat leaves of the Fidel variety.
    Type: Grant
    Filed: July 17, 1992
    Date of Patent: July 11, 1995
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Fiona Gruninger, Erich Hochuli, Peter K. Matzinger
  • Affinity peptides
    Patent number: 5310663
    Abstract: Fusion proteins and a process for their purification by means of metal chelate affinity chromatography on NTA resins are provided by this invention.
    Type: Grant
    Filed: June 18, 1993
    Date of Patent: May 10, 1994
    Assignee: Hoffman-La Roche Inc.
    Inventors: Heinz Dobeli, Bernhard Eggimann, Reiner Gentz, Erich Hochuli, Dietrich Stuber
  • Affinity peptides
    Patent number: 5284933
    Abstract: Fusion proteins and a process for their purification by means of metal chelate affinity chromatography on NTA resins are provided by this invention.
    Type: Grant
    Filed: February 22, 1988
    Date of Patent: February 8, 1994
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Heinz Dobeli, Bernhard Eggimann, Reiner Gentz, Erich Hochuli, Dietrich Stuber
  • Adsorbent for protein purification
    Patent number: 4716219
    Abstract: Adsorbents, which are suitable for the affinity chromatography of proteins, especially of interferons, and which consist of an electroneutral carrier matrix, --O--CH.sub.2 --CH(OH)--CH.sub.2 --NH- groups as the spacer and a triazine coloring substance bonded to the spacer.
    Type: Grant
    Filed: January 23, 1986
    Date of Patent: December 29, 1987
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Bernhard Eggimann, Erich Hochuli, Alfred Schacher
  • Leucine derivatives
    Patent number: 4598089
    Abstract: Novel compounds of the formula ##STR1## wherein A signifies the group ##STR2## or --(CH.sub.2).sub.5 --, which inhibit pancreas lipase and can be used for the control or prevention of obesity and hyperlipaemia, are disclosed. The inventive compounds can be produced by the cultivation of microorganism Streptomyces toxytricini, identified as NRRL 15443.
    Type: Grant
    Filed: June 18, 1984
    Date of Patent: July 1, 1986
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Paul Hadvary, Erich Hochuli, Ernst Kupfer, Hans Lengsfeld, Ernst K. Weibel
  • Purification of interferon by metal chelate chromatography
    Patent number: 4551271
    Abstract: The purification of solutions of recombinant interferons is achieved by chromatography on metal chelate resins of the formula ##STR1## in which Me represents copper or nickel.
    Type: Grant
    Filed: February 27, 1984
    Date of Patent: November 5, 1985
    Assignee: Hoffmann-La Roche Inc.
    Inventor: Erich Hochuli