Patents by Inventor Erich Hoffmann
Erich Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7788397Abstract: A personal computer's (PC) microprocessor is used to provide both the physical layer (PHY) and media access control (MAC) processing functions required to implement a wireless local area network (WLAN) adapter. This technique uses the polling mechanism associated with the power save (PS) functionality of WLAN protocol to relieve networking stress on the host processing system. It does this while maintaining networking integrity and packet delivery. The WLAN protocol polling mechanism is used to briefly inhibit the transfer of packets from the WLAN access point (AP) during peak periods of network traffic and/or host processor loading. Because the modulation, demodulation, and MAC functions, typically implemented in dedicated hardware on existing adapters are implemented in software running on the host PC microprocessor, other host system processes and applications can interfere with these time critical functions.Type: GrantFiled: July 23, 2003Date of Patent: August 31, 2010Inventors: Richard Douglas Schultz, George Rodney Nelson, Jr., John Erich Hoffmann
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Publication number: 20100208612Abstract: A personal computer's (PC) microprocessor is used to provide both the physical layer (PHY) and media access control (MAC) processing functions required to implement a wireless local area network (WLAN) adapter. This technique uses the polling mechanism associated with the power save (PS) functionality of WLAN protocol to relieve networking stress on the host processing system. It does this while maintaining networking integrity and packet delivery. The WLAN protocol polling mechanism is used to briefly inhibit the transfer of packets from the WLAN access point (AP) during peak periods of network traffic and/or host processor loading. Because the modulation, demodulation, and MAC functions, typically implemented in dedicated hardware on existing adapters are implemented in software running on the host PC microprocessor, other host system processes and applications can interfere with these time critical functions.Type: ApplicationFiled: May 3, 2010Publication date: August 19, 2010Inventors: Richard Douglas Schultz, George Rodney Nelson, JR., John Erich Hoffmann
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Patent number: 7577122Abstract: A method and wireless local area network (WLAN) adapter for the reduction of receive packet processing in a communications system receiver. The method includes establishing a set of criteria which identifies a packet as one requiring demodulation. The method further includes detecting a packet preamble to trigger at least one waveform identification function and determining with the at least one waveform identification function of the detected packet meets an established criteria for demodulation. The established criteria may include at least one of data rate, modulation type, signal to noise ratio, or coding rate. If the detected packet meets the established criteria for demodulation, a host processor may be interrupted to begin demodulation.Type: GrantFiled: June 12, 2003Date of Patent: August 18, 2009Inventors: Richard Douglas Schultz, John Erich Hoffmann
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Patent number: 7532723Abstract: Tokens/keys are produced for wireless communications. These tokens/keys are used for watermarks, signature insertion, encryption and other uses. In one embodiment, contextual information is used to generate tokens/keys. The tokens/keys may be derived directly from the contextual information. The contextual information may be used in conjunction with other information to derive the tokens/keys. Tokens/keys may be exchanged between transmit/receive units. The exchange of these tokens/keys may be encrypted.Type: GrantFiled: November 23, 2004Date of Patent: May 12, 2009Assignee: InterDigital Technology CorporationInventors: Prabhakar R. Chitrapu, Alain Charles Louis Briancon, Akinlolu Oloruntosi Kumoluyi, Alan Gerald Carlton, Kiran Kumar S. Vanganuru, Richard Dan Herschaft, John Erich Hoffmann, John Thommana, Debashish Purkayastha, Guodong Zhang, Robert Lind Olesen, Alexander Reznik, TieJun Shan, Sung-Hyuk Shin, Amit Singhal
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Publication number: 20080311148Abstract: The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus.Type: ApplicationFiled: October 31, 2007Publication date: December 18, 2008Applicant: St. Jude Children's Research HospitalInventor: Erich Hoffmann
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Publication number: 20080311149Abstract: The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus.Type: ApplicationFiled: October 31, 2007Publication date: December 18, 2008Applicant: St. Jude Children's Research HospitalInventor: Erich Hoffmann
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Patent number: 7465456Abstract: Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid influenza virus expression system are provided. Additionally, the invention provides methods of producing influenza viruses with enhanced ability to replicate in embryonated chicken eggs and/or cells (e.g., Vero and/or MDCK) and further provides influenza viruses with enhanced replication characteristics. A method of producing a cold adapted (ca) influenza virus that replicates efficiently at, e.g., 25° C. (and immunogenic compositions comprising the same) is also provided.Type: GrantFiled: May 20, 2005Date of Patent: December 16, 2008Assignee: MedImmune, LLCInventors: Erich Hoffmann, Hong Jin, Bin Lu, Gregory Duke, George Kemble, Zhongying Chen
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Publication number: 20080233560Abstract: The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus.Type: ApplicationFiled: October 31, 2007Publication date: September 25, 2008Applicant: St. Jude Children's Research HospitalInventor: Erich Hoffmann
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Patent number: 7415043Abstract: A spread spectrum method and apparatus for protecting and authenticating wirelessly transmitted digital information using numerous techniques. The apparatus may be a wireless code division multiple access (CDMA) communication system, a base station, a wireless transmit/receive unit (WTRU), a transmitter, a receiver and/or an integrated circuit (IC). The wireless CDMA communication system includes a transmitter which steganographically embeds digital information in a CDMA communication signal and wirelessly transmits the CDMA communication signal. The system further includes a receiver which receives the CDMA communication signal and extracts the steganographically embedded digital information from the received CDMA communication signal.Type: GrantFiled: January 13, 2005Date of Patent: August 19, 2008Assignee: InterDigital Technology CorporationInventors: John David Kaewell, Jr., Prabhakar R. Chitrapu, Robert Lind Olesen, Sung-Hyuk Shin, John Erich Hoffmann, Alexander Reznik
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Publication number: 20080118531Abstract: A vaccine composition and method which is effective in preventing or ameliorating Avian Influenza Virus infection is set forth herein. The vaccine contains at least two inactivated strains of avian influenza virus, wherein the combined hemagglutinin (HA) total is at least about 200 HA/dose of the vaccine composition, and wherein each of the strains presents at least about 128 HA/dose, and further wherein one of the strains has the same HA subtype as that of a challenge virus, and wherein at least one of the strains has a different NA subtype than the challenge virus.Type: ApplicationFiled: April 18, 2007Publication date: May 22, 2008Applicants: Wyeth, St. Jude Children's Research HospitalInventors: Erich Hoffmann, Scott L. Krauss, Mahesh Kumar, Richard J. Webby, Robert G. Webster
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Patent number: 7312064Abstract: The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus.Type: GrantFiled: March 29, 2005Date of Patent: December 25, 2007Assignee: St. Jude Children's Research HosptalInventor: Erich Hoffmann
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Publication number: 20070031453Abstract: The immunogenicity of the influenza virus hemagglutinin (HA) molecule may be increased by substitutions of amino acids in the HA sequence. The substitution of specific HA residues, such as asparagine at position 223 of H5 HA, increase the sensitivity of the hemagglutinin inhibition (HI) assay by altering receptor specificity and/or antibody-antigen binding. HA molecules containing such substitutions will be useful in the development of diagnostic reference viruses and improved influenza vaccines.Type: ApplicationFiled: July 27, 2006Publication date: February 8, 2007Inventors: Erich Hoffmann, Aleksandr Lipatov, Richard Webby, Elena Govorkova, Robert Webster
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Publication number: 20070010259Abstract: The current location and bearing of a wireless transmit/receive unit (WTRU) are determined. Next, signal quality measurements of a pre-determined geographic region are taken. This geographic region includes the current location of the WTRU. From these quality measurements, a signal quality profile is generated. The signal quality profile and a directional guidance indicator are then displayed to the user of the WTRU. The display indicates areas of preferred signal quality relative to the current location of the WTRU.Type: ApplicationFiled: August 23, 2005Publication date: January 11, 2007Applicant: InterDigital Technology CorporationInventor: John Erich Hoffmann
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Publication number: 20050266026Abstract: Vectors and methods for the production of influenza viruses suitable as recombinant influenza vaccines in cell culture are provided. Bi-directional expression vectors for use in a multi-plasmid influenza virus expression system are provided. Additionally, the invention provides methods of producing influenza viruses with enhanced ability to replicate in embryonated chicken eggs and/or cells (e.g., Vero and/or MDCK) and further provides influenza viruses with enhanced replication characteristics. A method of producing a cold adapted (ca) influenza virus that replicates efficiently at, e.g., 25° C. (and immunogenic compositions comprising the same) is also provided.Type: ApplicationFiled: May 20, 2005Publication date: December 1, 2005Inventors: Erich Hoffmann, Hong Jin, Bin Lu, Gregory Duke, George Kemble, Zhongying Chen
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Patent number: 6951754Abstract: The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuramimidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus.Type: GrantFiled: April 27, 2001Date of Patent: October 4, 2005Assignee: St. Jude Children's Research HospitalInventor: Erich Hoffmann
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Publication number: 20050186563Abstract: The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus.Type: ApplicationFiled: March 29, 2005Publication date: August 25, 2005Applicant: St. Jude Children's Research HospitalInventor: Erich Hoffmann
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Publication number: 20020164770Abstract: The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus.Type: ApplicationFiled: April 27, 2001Publication date: November 7, 2002Applicant: St. Jude Children's Research HospitalInventor: Erich Hoffmann
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Patent number: 6400317Abstract: An antenna apparatus for increasing the capacity in a cellular communication system. The antenna operates in conjunction with a mobile subscriber unit and provides a plurality of antenna elements, each coupled to a respective signal control component to provide a weight to the signal transmitted from each element. The weight for each antenna element is adjusted to achieve optimum reception during, for example, an idle mode when a pilot signal is received. The weight values cause the antenna array to create a beam former for signals to be transmitted from the mobile subscriber unit, and a directional receiving array to more optimally detect and receive signals transmitted from the base station. By directionally receiving and transmitting signals, multipath fading and intercell interference are greatly reduced. The weights are adjusted at the transmitting site in accord with signal quality metric information determined at the receiving site.Type: GrantFiled: February 2, 2001Date of Patent: June 4, 2002Assignee: Tantivy Communications, Inc.Inventors: Antoine J. Rouphael, Daniel Innis Riley, John Erich Hoffmann, George Rodney Nelson, Jr., James Arthur Proctor, Jr.
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Publication number: 20010026880Abstract: Tape-like magnetic recording media having a nonmagnetic substrate and at least one layer applied to the substrate having incorporated into at least one of these layers, an inorganic needle-shaped pigment which serves as a supporting pigment and has a ratio of the average length to the average diameter of the pigment of at least 3, and the mean modulus of elasticity of the layers is not less than 15 Gpa in the longitudinal direction of the tape-like recording media.Type: ApplicationFiled: March 19, 2001Publication date: October 4, 2001Inventors: August Lehner, Helmut Jakusch, Volker Koch, Manfred Ohlinger, Albert Kohl, Werner Lenz, Norbert Schneider, Peter Heilmann, Werner Hubner, Erich Hoffmann, Ronald John Veitch, Rudi Lehnert, Harald Jachow
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Publication number: 20010022557Abstract: An antenna apparatus for increasing the capacity in a cellular communication system. The antenna operates in conjunction with a mobile subscriber unit and provides a plurality of antenna elements, each coupled to a respective signal control component to provide a weight to the signal transmitted from each element. The weight for each antenna element is adjusted to achieve optimum reception during, for example, an idle mode when a pilot signal is received. The weight values cause the antenna array to create a beam former for signals to be transmitted from the mobile subscriber unit, and a directional receiving array to more optimally detect and receive signals transmitted from the base station. By directionally receiving and transmitting signals, multipath fading and intercell interference are greatly reduced. The weights are adjusted at the transmitting site in accord with signal quality metric information determined at the receiving site.Type: ApplicationFiled: February 2, 2001Publication date: September 20, 2001Inventors: Antoine J. Rouphael, Daniel Innis Riley, John Erich Hoffmann, George Rodney Nelson, James Arthur Proctor