Patents by Inventor Erich Jaeger
Erich Jaeger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11059865Abstract: Disclosed are catalytically active water-insoluble protein aggregates comprising fusion proteins which comprise a coiled-coil domain and a catalytic domain, methods of manufacturing such protein aggregates, and their use.Type: GrantFiled: July 22, 2016Date of Patent: July 13, 2021Assignee: evoxx technologies GmbHInventors: Martina Pohl, Karl-Erich Jaeger, Martin Diener, Ulrich Krauss
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Publication number: 20200087355Abstract: Disclosed are catalytically active water-insoluble protein aggregates comprising fusion proteins which comprise a coiled-coil domain and a catalytic domain, methods of manufacturing such protein aggregates, and their use.Type: ApplicationFiled: July 22, 2016Publication date: March 19, 2020Inventors: Martina Pohl, Karl-Erich Jaeger, Martin Diener, Ulrich Krauss
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Publication number: 20160298095Abstract: The present invention relates to the improved production of proteins, preferably enzymes such as lipases. In particular, the invention relates to a mutated signal peptide and nucleotide sequence encoding said signal peptide that results in an increased protein secretion. Further, the invention relates to a mutated promoter that results in an increased protein expression. It was surprisingly found that the combination of the mutated signal peptide and the mutated promoter act synergistically to result in an about 100-fold increased protein production. Nucleic acid molecules, expression vectors and host cells comprising the mutated signal peptide, mutated promoter, or the combination thereof are also encompassed by the invention. Finally, the invention relates to methods and uses of such nucleic acid molecules, expression vectors and host cells for protein preparation.Type: ApplicationFiled: April 7, 2015Publication date: October 13, 2016Inventors: Andreas Knapp, Sonja Voget, Rolf Daniel, Karl-Erich Jaeger
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Patent number: 8956838Abstract: The present invention relates to a polynucleotide encoding an enzyme having carboxyl esterase [E.C. 2.1.1.1] activity.Type: GrantFiled: April 27, 2007Date of Patent: February 17, 2015Assignee: B.R.A.I.N.Inventors: Christian Elend, Karl-Erich Jaeger, Christian Leggewie, Christel Vollstedt, Wolfgang Streit
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Patent number: 8852882Abstract: A FRET donor-acceptor pair for use as a biosensor, comprising at least two fluorescence proteins, wherein at least one fluorescence protein is stable with respect to a parameter to be detected by the biosensor and at least one fluorescence protein is unstable with respect to the parameter to be detected by the biosensor.Type: GrantFiled: August 16, 2011Date of Patent: October 7, 2014Assignee: Evocatal GmbHInventors: Karl Erich Jaeger, Thomas Drepper, Stephan Endres, Janko Potzkei, Achim Heck, Franco Circolone
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Publication number: 20140227698Abstract: To investigate protein-protein interactions, protein foldings and protein localization and also in the secretion of proteins, in vivo reporter proteins are used in biotechnology and in basic research. In order to be able to utilize fluorescence reporters as markers for secretion processes, FMN-binding fluorescence proteins (FbFP) have been developed by us for the first time. The new fluorescence markers can be expressed like GFP in various bacteria. The binding of the chromophore FMN produces a cyan-green fluorescent protein which can be detected in vivo using all customary spectroscopic and microscopic methods. In contrast to GFP, this protein can also surprisingly be secreted via the Sec route and be converted to the fluorescence-active state in the periplasma.Type: ApplicationFiled: July 27, 2012Publication date: August 14, 2014Applicant: EVOCATAL GMBHInventors: Thomas Drepper, Karl-Erich Jaeger, Janko Potzkei
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Publication number: 20130280749Abstract: A FRET donor-acceptor pair for use as a biosensor, comprising at least two fluorescence proteins, wherein at least one fluorescence protein is stable with respect to a parameter to be detected by the biosensor and at least one fluorescence protein is unstable with respect to the parameter to be detected by the biosensor.Type: ApplicationFiled: August 16, 2011Publication date: October 24, 2013Applicant: EVOCATAL GMBHInventors: Karl Erich Jaeger, Thomas Drepper, Stephan Endres, Janko Potzkei, Achim Heck, Franco Circolone
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Publication number: 20130230885Abstract: The present invention relates to the use of a protein comprising an LOV domain for the photosensitive defunctionalization of a molecule and to a method for the photosensitive defunctionalization of a target molecule.Type: ApplicationFiled: August 16, 2011Publication date: September 5, 2013Applicant: EVOCATAL GMBHInventors: Karl Erich Jaeger, Thomas Drepper, Stephan Endres, Janko Potzkei
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Publication number: 20090221031Abstract: The present invention relates to a polynucleotide encoding an enzyme having carboxyl esterase [E.C. 3.1.1.Type: ApplicationFiled: April 27, 2007Publication date: September 3, 2009Applicant: B.R.A.I.N. AGInventors: Christian Elend, Karl-Erich Jaeger, Christian Leggewie, Christel Vollstedt, Wolfgang Streit
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Publication number: 20090104657Abstract: The invention relates to novel proteins, especially with protease activity, which promote the production of extracellular lipases by bacteria, especially of the genus Burkholderia, nucleic acid sequences encoding them, expression constructs containing them, hosts transformed with them, methods for the production of the proteins with protease activity and methods for the production of lipases, especially by bacteria of the genus Burkholderia.Type: ApplicationFiled: June 13, 2006Publication date: April 23, 2009Applicant: BASF AktiengesellschaftInventors: Anke Beselin, Frank Rosenau, Karl-Erich Jaeger, Michael Breuer, Bernhard Hauer
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Patent number: 6283466Abstract: An apparatus for producing multi-part printed products comprising an upwardly open V-shaped continuous conveying channel (1), and a V-shaped processing channel (2) arranged above the conveying channel (1). A plurality of supply locations (11-17) are arranged serially along the processing route for supplying the printed product parts (A-G). The processing channel (2) has individual successive processing regions (3-10) which receive the product parts supplied at the supply locations and between which through-passages (18, 19, 119, 20, 120) are provided which open toward the bottom and by means of which the product parts (A-G) pass out of the processing region and into the underlying conveying channel (1).Type: GrantFiled: August 13, 1999Date of Patent: September 4, 2001Assignee: Ferag AGInventor: Erich Jaeger
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Patent number: 6279891Abstract: A processing line for printed products 18 which comprises a number of component modules 10, 12, 14, 34, 36, 46 which are arranged directly one behind the other in the direction of processing V. The printed products are supplied to the line at sequential locations so that the products are processing and/or combined to form intermediate or end products which are delivered to a removal location. The printed products are conveyed along the processing line by a conveyor 20, 20′. The component modules can be separated from one another, and the conveyor is composed of conveying elements 98 which can be separated when the component modules are separated such that at least one conveying element remains in each of the component modules.Type: GrantFiled: August 17, 1999Date of Patent: August 28, 2001Assignee: Ferag AGInventor: Erich Jaeger
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Patent number: 6173555Abstract: Discrete lengths of a web (1) of sample bags are each arranged in a container in an ordered manner such that each web can be removed from its container (13) without additional aids by pulling on a head end (A) of the web length, and so that the tail end (E) of each such web length can also be gripped without changing the web arrangement in the container and independently of the fullness of the container. For feeding sample bags into a processing station, a first container is positioned in the region of the feeding location and the head end (A) of the web length is pulled out of its container and led to a feeding mechanism of the processing station. During the feeding of the first web length of bags into the processing, further containers are formed into a series of containers by connecting the tail end (E) of the web in one container to the head end (A) of a web length in the following container.Type: GrantFiled: December 9, 1999Date of Patent: January 16, 2001Assignee: Ferag AGInventors: Erich Jaeger, Markus Scheuber
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Patent number: 6095510Abstract: A printed product (70) is produced from a plurality of product parts (71, 73, 75) consisting each of a plurality of sheets folded inside each other, by collating the folded product parts in a stack and by stitching the stack along a stitching line running parallel to the spine of the product with a distance from the spine chosen such that the innermost sheet of each product part is fixed by the stitching. Between the product parts (71, 73, 75) and/or on the outer sides of the stack of product parts, additional products (72, 74) and/or cover leafs or cover sheets may be added and fixed to the product parts with the same stitching.Type: GrantFiled: June 17, 1997Date of Patent: August 1, 2000Assignee: Ferag AGInventor: Erich Jaeger
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Patent number: 6029819Abstract: Discrete lengths of a web (1) of sample bags are each arranged in a container in an ordered manner such that each web can be removed from its container (13) without additional aids by pulling on a head end (A) of the web length, and so that the tail end (E) of each such web length can also be gripped without changing the web arrangement in the container and independently of the fullness of the container. For feeding sample bags into a processing station, a first container is positioned in the region of the feeding location and the head end (A) of the web length is pulled out of its container and led to a feeding mechanism of the processing station. During the feeding of the first web length of bags into the processing, further containers are formed into a series of containers by connecting the tail end (E) of the web in one container to the head end (A) of a web length in the following container.Type: GrantFiled: May 11, 1998Date of Patent: February 29, 2000Assignee: Ferag AGInventors: Erich Jaeger, Marcus Scheuber
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Patent number: 6017027Abstract: Flexible, sheet products which are to be opened have a first product part and a second product part. The product parts are connected to one another at a connecting edge, and the first product part has a border region which projects beyond the second product part. The products are conveyed with a leading edge running obliquely with respect to the conveying direction. An end section of the leading edge abuts a fixed stop wherein the first product part is arched in a lateral corner region. This results in the second product part lifting off from the first product part so as to define an opening. As the products are further conveyed, a holding-open element is inserted into the opening to maintain the first product part separate from the second product part. After the arching operation, the first product part springs over the stop and is further conveyed with the second product part.Type: GrantFiled: August 28, 1997Date of Patent: January 25, 2000Assignee: Ferag AGInventor: Erich Jaeger
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Patent number: 5944189Abstract: Sample bags are produced from webs of film material by forming longitudinal seams and longitudinally spaced transverse seams and by filling the bags with a sample product between forming the transverse seams. In order to make the bags easier to handle, the longitudinal seams are thickened so that the thickness of the seams is equal to the thickness of the center of the bag. Thickening is done by rolling or folding the seams or by adding frames or strips of additional material either between or outside the seam or interior portions of the webs. The resulting bags are more easily stacked, handled and inserted into publications for distribution.Type: GrantFiled: December 31, 1997Date of Patent: August 31, 1999Assignee: Ferag AGInventors: Juerg Vollenweider, Erich Jaeger, Werner Heuberger