Abstract: Method and apparatus for estimating damage to an object, with at least a first parameter which corresponds to an operational state for the object and at least a second parameter which corresponds to a condition during the operational state being determined by at least one operation measurement, and with such measurement being carried out repeatedly. A total load that is defined by the total influence of the first and second parameters on the life of the object is then calculated. The invention also relates to a method and a system for controlling the use of the object.

Abstract: Transmission method and arrangement for distributing tractive force in a vehicle between a first transmission branch (28a) and a second transmission branch (30). The transmission branches are connected to one another by way of a fork (28b) and one transmission branch (28a) is directly connectable to at least one wheel contact surface. The second transmission branch (30) is connected to the fork (28b) by way of a control unit (19), which is provided with control means (27) for varying the transmission ratio in this branch (30). The invention furthermore relates to a vehicle having at least two driving wheels (16, 16b, 17, 17b, 18, 18b) and the transmission arrangement specified above.

Abstract: The present invention relates to a novel pharmaceutical composition as a solid dosage form comprising desmopressin as a therapeutically active ingredient, and to a method for manufacturing thereof. The invention relates to a pharmaceutical composition as a solid dosage form comprising desmopressin, or a pharmaceutically acceptable salt thereof, as a therapeutically active ingredient together with a pharmaceutically acceptable excipient, diluent or carrier, or mixture thereof, wherein at least one of said excipient, diluent and carrier is a substance selected from a monosaccharide, disaccharide, oligosaccharide and a polysaccharide, wherein the said substance has an average particle size in the range of from 60 to 1,000 ?m. A method according to the present invention provides an improved production of solid dosage forms of desmopressin.

Abstract: The present invention relates to a novel pharmaceutical composition as a solid dosage form comprising desmopressin as a therapeutically active ingredient, and to a method for manufacturing thereof. The invention relates to a pharmaceutical composition as a solid dosage form comprising desmopressin, or a pharmaceutically acceptable salt thereof, as a therapeutically active ingredient together with a pharmaceutically acceptable excipient, diluent or carrier, or mixture thereof, wherein the pharmaceutical composition is composed of a compressed granulate and contains lubricant in an amount of from 0.05 to less than 0.50 percent by weight of said pharmaceutical composition.

Abstract: The present invention relates to a novel pharmaceutical composition as a solid dosage form comprising desmopressin as a therapeutically active ingredient, and to a method for manufacturing thereof. The invention relates to a pharmaceutical composition as a solid dosage form comprising desmopressin, or a pharmaceutically acceptable salt thereof, as a therapeutically active ingredient together with a pharmaceutically acceptable excipient, diluent or carrier, or mixture thereof, wherein at least one of said excipient, diluent and carrier is a substance selected from a monosaccharide, disaccharide, oligosaccharide and a polysaccharide, wherein the said substance has an average particle size in the range of from 60 to 1,000 ?m. A method according to the present invention provides an improved production of solid dosage forms of desmopressin.

Abstract: A system and method for providing polarization-independent optical sampling utilizes a differential group delay (DGD) element to split a sampling pulse source (SPS) into orthogonal components by controlling the state of polarization of the SPS at the DGD element input. The orthogonally-polarized sampling pulse components then each interact with the input optical signal waveform in a polarization-dependent sampling gate, creating two samples for each original sampling pulse. The generated samples are converted into the electrical domain by a photodetector with an impulse response time longer than that associated with the DGD element, resulting in a single impulse response representing the combined energy of the two samples that is independent of the state of polarization of the input optical signal waveform.

Abstract: Method and apparatus for estimating damage to an object, with at least a first parameter which corresponds to an operational state for the object and at least a second parameter which corresponds to a condition during the operational state being determined by at least one operation measurement, and with such measurement being carried out repeatedly. A total load that is defined by the total influence of the first and second parameters on the life of the object is then calculated. The invention also relates to a method and a system for controlling the use of the object.

Abstract: The present invention relates to a novel pharmaceutical composition as a solid dosage form comprising desmopressin as a therapeutically active ingredient, and to a method for manufacturing thereof. The invention relates to a pharmaceutical composition as a solid dosage form comprising desmopressin, or a pharmaceutically acceptable salt thereof, as a therapeutically active ingredient together with a pharmaceutically acceptable excipient, diluent or carrier, or mixture thereof; wherein the pharmaceutical composition is composed of a compressed granulate and contains lubricant in an amount of from 0.05 to less than 0.50 percent by weight of said pharmaceutical composition.

Abstract: The present invention relates to a novel method for the preparation of a solid dosage form of desmopressin, or a pharmaceutically acceptable salt thereof, comprising providing a desmopressin containing granulate suitable for compression to a pharmaceutically acceptable tablet, as well as to solid dosage forms, preferably tablets, obtainable by said method.

Abstract: The present invention relates to a novel method for the preparation of a solid dosage form of desmopressin, or a pharmaceutically acceptable salt thereof, comprising providing a desmopressin containing granulate suitable for compression to a pharmaceutically acceptable tablet, as well as to solid dosage forms, preferably tablets, obtainable by said method.

Abstract: A suite of optical performance monitoring (OPM) methods, based on optical subcarrier multiplexing, are described by the invention. The strength of this approach lies in the simplicity of double sideband subcarrier signals and the fact that these signals travel the complete optical path with the baseband signal of interest. The subcarrier signals can be recovered using techniques described in the application and are immune to fiber dispersion induced fading.

Abstract: The present invention relates to a device for fixation to a patient during neurological diagnosis, therapy or surgery, in particular during MRI diagnosis. The device comprises at least one fixation pin being made of a non-magnetic, electrically conductive material for fixation to a patient, and at least one pin support member for supporting said fixation pin. An insulation means is arranged so as to restrict the electrical coupling between said pin support member and fixation pin. Said insulation means is sleeve shaped and arranged to at least partly surround said fixation pin. The invention also relates to an insulation means, a pin support member and to a method for assembling a fixation device.

Abstract: Method and arrangements for predicting life-affecting damage on a rotary member subjected to repeated loading during operation. A number of operating parameters are measured, and a temperature increase during each loading is calculated from the operating parameters. More precisely, a total temperature in a part of the rotary member is calculated for each loading by summation of basic temperature of the rotary member before the loading concerned and the temperature increase, and the values for the total temperature are used as a measure of the damage. The part of the rotary member for which the total temperature is calculated defines a surface that is acted on when the rotary member is loaded. Two sets of predetermined functions (M, N), which each comprise at least one function, are used for temperature-increase calculation, and the set which is used for temperature-increase calculation is selected depending on at least the nature of the rotary member.

Abstract: The present invention relates to a novel pharmaceutical composition as a solid dosage form comprising desmopressin as a therapeutically active ingredient, and to a method for manufacturing thereof. The invention relates to a pharmaceutical composition as a solid dosage form comprising desmopressin, or a pharmaceutically acceptable salt thereof, as a therapeutically active ingredient together with a pharmaceutically acceptable excipient, diluent or carrier, or mixture thereof; wherein the pharmaceutical composition is composed of a compressed granulate and contains lubricant in an amount of from 0.05 to less than 0.50 percent by weight of said pharmaceutical composition.

Abstract: Method and apparatus for estimating damage to an object, with at least a first parameter which corresponds to an operational state for the object and at least a second parameter which corresponds to a condition during the operational state being determined by at least one operation measurement, and with such measurement being carried out repeatedly. A total load that is defined by the total influence of the first and second parameters on the life of the object is then calculated. The invention also relates to a method and a system for controlling the use of the object.

Abstract: The present invention relates to a novel pharmaceutical composition as a solid dosage form comprising desmopressin as a therapeutically active ingredient, and to a method for manufacturing thereof. The invention relates to a pharmaceutical composition as a solid dosage form comprising desmopressin, or a pharmaceutically acceptable salt thereof, as a therapeutically active ingredient together with a pharmaceutically acceptable excipient, diluent or carrier, or mixture thereof, wherein at least one of said excipient, diluent and carrier is a substance selected from a monosaccharide, disaccharide, oligosaccharide and a polysaccharide, wherein the said substance has an average particle size in the range of from 60 to 1,000 &mgr;m. A method according to the present invention provides an improved production of solid dosage forms of desmopressin.

Abstract: Transmission method and arrangement for distributing tractive force in a vehicle between a first transmission branch (28a) and a second transmission branch (30). The transmission branches are connected to one another by way of a fork (28b) and one transmission branch (28a) is directly connectable to at least one wheel contact surface. The second transmission branch (30) is connected to the fork (28b) by way of a control unit (19), which is provided with control means (27) for varying the transmission ratio in this branch (30). The invention furthermore relates to a vehicle having at least two driving wheels (16, 16b, 17, 17b, 18, 18b) and the transmission arrangement specified above.

Abstract: The present invention relates to a spectrometer module comprising an input, for receiving an incoming optical signal, a variable differential group delay (DGD) element, for applying a variable birefringence retardation to said incoming optical signal, and a detector unit for detecting the power of a signal exiting said variable DGD element, having a defined state of polarization. It also relates to a monitor module, a monitoring unit and a monitoring system, comprising such a spectrometer module for use in monitoring an optical network. Further, the invention relates to a spectrometer device, for spectrometry purposes, comprising a spectrometer module as stated above.

Abstract: An adhesive protein, present inter alia in the stickleback nest building glue has now been isolated and purified. Its amino acid sequence and corresponding coding polynucleotide sequences are isolated and sequenced. The protein finds both medical and technical uses, whereas both the protein and the polynucleotide sequence can be used in analyses, determining the presence and influence of androgenic substances, for example androgenic pollutants, present in the aquatic environment.

Abstract: The invention relates to a process for continuous cooking of wood chips at elevated pressure and temperature in a vertical digester (1) for production of chemically dissolved pulp. Fiber material and cooking liquor are introduced at the top of the digester and pulp is discharged from the bottom of the digester (1), via a line (8) in which the pulp is maintained at substantially the same pressure level, to a pressurized wash (7). More than 50% of the used cooking liquor (black liquor) which is extracted from the system in total is extracted from the wash filtrate of the pressurized wash. The pressurized wash is regulated so that a high temperature is maintained in the wash filtrate. The extraction is regulated so that a net co-current flow is established at the bottom of the digester.