Abstract: The present invention relates to protease variants, polynucleotides encoding said variants, nucleic acid constructs and expression vectors comprising said polynucleotides, host cells expressing said variants, methods of obtaining the variants, detergent compositions comprising said variants, and use of said variants or said detergent compositions.

Abstract: Method and system for extracting metadata from an observed scene comprising the use of high-speed image sensor array observing the scene through a field-of-view, filtering, matching of interesting information defined as activity/incident in the observed scene with a predefined-library, adapting the filtering to enhance frequencies of interest and suppress all others, and extracting metadata of interest.

Abstract: The present invention relates to methods and compositions for the delivery of cosmetics and medicants. In some embodiments, the invention relates to compositions comprising both hydrophobic and hydrophilic polymers. In preferred embodiments, the invention relates to the delivery of peptides, small molecules and other bioactive compounds using the compositions and methods disclosed herein.

Abstract: A system for reducing strain on a vehicle door comprises the vehicle door. The vehicle door comprises an inner panel and a division bar comprising a first portion and a second portion. The system further comprises a relief bracket configured to reduce strain on the inner panel when the vehicle door is closed. The relief bracket comprises a first portion coupled to the second portion of the division bar, a second portion coupled to the inner panel, and a relief portion extending between the first portion and the second portion.

Abstract: A centrifugal separator for industrial separation of a liquid-gas mixture, including a centrifugal separator body having a centrifugal separator body wall, the centrifugal separator body including a cylindrical section and a conical section, a gas outlet positioned at the top end of the centrifugal separator body and a liquid outlet positioned at the bottom end of the centrifugal separator body, the centrifugal separator body further including a liquid-gas mixture inlet orifice, positioned in the cylindrical section of the centrifugal separator body, and a detector for detecting the thickness of the liquid on the centrifugal separator body wall, wherein the detector is positioned in the cylindrical section. A method for monitoring the flow through such a centrifugal separator.

Abstract: A system for reducing strain on a vehicle door comprises the vehicle door. The vehicle door comprises an inner panel and a division bar comprising a first portion and a second portion. The system further comprises a relief bracket configured to reduce strain on the inner panel when the vehicle door is closed. The relief bracket comprises a first portion coupled to the second portion of the division bar, a second portion coupled to the inner panel, and a relief portion extending between the first portion and the second portion.

Abstract: The present invention relates to methods and compositions for the delivery of cosmetics and medicants. In some embodiments, the invention relates to compositions comprising both hydrophobic and hydrophilic polymers. In preferred embodiments, the invention relates to the delivery of peptides, small molecules and other bioactive compounds using the compositions and methods disclosed herein.

Abstract: The present invention relates to methods and compositions for the delivery of cosmetics and medicants. In some embodiments, the invention relates to compositions comprising both hydrophobic and hydrophilic polymers. In preferred embodiments, the invention relates to the delivery of peptides, small molecules and other bioactive compounds using the compositions and methods disclosed herein.

Abstract: Interaction between development environments and runtime environments to ensure that underlying process components are in an acceptable state before deploying application updates. A deploy state monitor in a development environment interacts with runtime values in executing applications to manage deployment requests and states of executing applications.

Abstract: Interaction between development environments and runtime environments to ensure that underlying process components are in an acceptable state before deploying application updates. A deploy state monitor in a development environment interacts with runtime values in executing applications to manage deployment requests and states of executing applications.

Abstract: The present invention relates to methods and compositions for the delivery of cosmetics and medicants. In some embodiments, the invention relates to compositions comprising both hydrophobic and hydrophilic polymers. In preferred embodiments, the invention relates to the delivery of peptides, small molecules and other bioactive compounds using the compositions and methods disclosed herein.

Abstract: The present invention relates to methods and compositions for the delivery of cosmetics and medicants. In some embodiments, the invention relates to compositions comprising both hydrophobic and hydrophilic polymers. In preferred embodiments, the invention relates to the delivery of peptides, small molecules and other bioactive compounds using the compositions and methods disclosed herein.

Abstract: Novel compounds which interact with the histamine H3 receptor are defined. These compounds are particularly useful in the treatment of a variety of diseases or conditions in which histamine H3 interactions are beneficial. Thus, the compounds may find use, e.g., in the treatment of diseases of the central nervous system, the peripheral nervous system, the cardiovascular system, the pulmonary system, the gastrointestinal system and the endocrinological system. The novel compounds have a core consisting of a 6 membered aromatic ring containing at least one nitrogen atom and two carbon atoms in the ring and, at the remaining positions in the ring, there is either a carbon or a nitrogen atom.

Abstract: Novel compounds which interact with the histamine H3 receptor are defined. These compounds are particularly useful in the treatment of a variety of diseases or conditions in which histamine H3 interactions are beneficial. Thus, the compounds may find use, e.g., in the treatment of diseases of the central nervous system, the peripheral nervous system, the cardiovascular system, the pulmonary system, the gastrointestinal system and the endocrinological system. The novel compounds have a core consisting of a 6 membered aromatic ring containing at least one nitrogen atom and two carbon atoms in the ring and, at the remaining positions in the ring, there is either a carbon or a nitrogen atom.

Abstract: Certain novel benzothiazoles and benzoxazoles, e.g., 2-(piperazin-1-yl)benzothiazoles and 2-(piperazin-1-yl)benzoxazoles, optionally substituted in the 3 and/or 4 positions of the piperazine rings, having histamine H3 antagonistic activity can be used in pharmaceutical compositions.

Abstract: Certain novel benzothiazoles and benzoxazoles, e.g., 2-(piperazin-1-yl)benzothiazoles and 2-(piperazin-1-yl)benzoxazoles, optionally substituted in the 3 and/or 4 positions of the piperazine rings,! of the general formula (1): having histamine H3 antagonistic activity can be used in pharmaceutical compositions.

Abstract: A method and system for searching and collecting electronically stored information are described. Consistent with an embodiment of the invention, configuration and execution of a search are separated in time and location. For example, a search configuration application executing at a first computer system is utilized to generate a search configuration file, which controls the operation of a search agent when the search agent is executing at a target computer system and performing a search of storage devices act of the target computer system. Encryption is utilized to prevent unauthorized access to the search configuration file as well as the search results file generated by the search agent.

Abstract: Novel compounds which interact with the histamine H3 receptor are defined. These compounds are particularly useful in the treatment of a variety of diseases or conditions in which histamine H3 interactions are beneficial. Thus, the compounds may find use, e.g., in the treatment of diseases of the central nervous system, the peripheral nervous system, the cardiovascular system, the pulmonary system, the gastrointestinal system and the endocrinological system. The novel compounds have a core consisting of a 6 membered aromatic ring containing at least one nitrogen atom and two carbon atoms in the ring and, at the remaining positions in the ring, there is either a carbon or a nitrogen atom.

Abstract: An expandable stent comprising a tubular body made up of a plurality of separated tubular elements (1) arranged along a common longitudinal axis. Each tubular element (1) comprises a plurality of rhombic-shaped closed cell elements (2) joined by circumferentially extending linking members (3). The closed cell elements (2) are expandable to allow the tubular elements, and hence the stent itself, to expand. In the direction of the longitudinal axis of the stent, the extremities of each of the closed cell elements has an enlarged loop (30) with waisted portions (33) which allow the tubular elements to interlock to create a stable structure, at least when in the unexpanded condition.

Abstract: An apparatus for processing crustaceans comprising a feeder for feeding crustaceans to a singulating and conveying device, said singulating and conveying device delivering the crustaceans individually to at least one separating device, said at least one separating device separating the tail section of each crustacean from the head section thereof.