Patents by Inventor Erik Anna Biessen

Erik Anna Biessen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7531516
    Abstract: The present invention relates to compounds which bind selectively to the adhesion molecule human P-selectin, and particularly to such compounds comprising a peptide with an amino acid sequence XAxA3A1A2A1Y, or a functional equivalent of said peptide. In addition, the invention relates to methods for preparing such compounds, to the use of such compounds in therapeutic or diagnostic methods and in pharmaceutical compositions, to nucleic acids encoding for proteinaceous materials comprising the amino acid sequences of said compounds, to gene delivery vehicles comprising such nucleic acids, to binding molecules binding to said compounds, and to a method for determining whether a compound is capable of binding to P-selectin.
    Type: Grant
    Filed: August 28, 2002
    Date of Patent: May 12, 2009
    Assignee: Astellas Pharma Europe B.V.
    Inventors: Thomas Jacobus Maria Molenaar, Johan Kuiper, Theodorus Josephus Cornelis Van Berkel, Erik Anna Biessen
  • Publication number: 20060276545
    Abstract: Polyhydroxy phenols, which are non-peptidic mimetics of galloyl peptides, and a process for the preparation of gallic acid derivatives using a gallic-acid providing moiety are provided as well as polyhydroxy phenol-containing pharmaceutical and nutraceutical compositions. The use of polyhydroxy phenols as a medicament and especially for the manufacture of a medicament for the prevention, treatment or diagnosis of a disease or a condition, wherein P-selectin is involved, is provided. The same compounds can also be used as targeting tools to P-selectin expressing cells or tissues in a composition, further comprising an active compound in a vehicle.
    Type: Application
    Filed: May 7, 2004
    Publication date: December 7, 2006
    Applicant: YAMANOUCHI PHARMACEUTICAL CO., LTD.
    Inventors: Erik Anna Biessen, Chantal Appeldoorn, Arnaud Bonnefoy, Theodorus Van Berkel, Johan Kuiper, Marc Hoylaerts
  • Publication number: 20060217294
    Abstract: The present invention relates to derivatives of compounds which bind selectively to the adhesion molecule human P-selectin, and particularly to such derivatives which comprise a peptide moiety or a functional equivalent of said peptide moiety and are represented by X(Ax)mA3A1A2A1Y. In addition, the invention relates to methods for preparing such compounds, to the use of such compounds in therapeutic or diagnostic methods and in pharmaceutical compositions, to binding molecules binding to said compounds and to a method for determining whether a compound is capable of binding to P-selectin.
    Type: Application
    Filed: July 4, 2003
    Publication date: September 28, 2006
    Inventors: Chantal Appeldoorn, Erik Anna Biessen, Thomas Molenaar, Johan Kuiper, Theodorus Van Berkel