Patents by Inventor Erik B. JUE

Erik B. JUE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidic measurements of the response of an organism to a drug
    Patent number: 11542545
    Abstract: Disclosed herein are methods and devices for rapid assessment of whether a microorganism present in a sample is susceptible or resistant to a treatment.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: January 3, 2023
    Assignees: California Institute of Technology, Talis Biomedical Corporation
    Inventors: Rustem F. Ismagilov, Eugenia Khorosheva, Travis S. Schlappi, Matthew S. Curtis, Nathan G. Schoepp, Hedia Maamar, Feng Shen, Erik B. Jue
  • Devices and methods for direct visual detection and readout of single nucleic acid molecules
    Patent number: 10866184
    Abstract: The present invention relates to methods, computer readable medium and systems for detecting and counting single nucleic acid molecules confined in nanoliter volumes using an unmodified camera, such as a cell phone camera. In particular, it identifies colorimetric amplification-indicator dyes that are compatible with the spectral sensitivity of standard mobile phones. The invention further provides an optimal ratiometric image-process for a selected dye to achieve a readout that is robust to lighting conditions and camera hardware and provides unambiguous quantitative results, even for colorblind users.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: December 15, 2020
    Assignee: California Institute of Technology
    Inventors: Rustem F. Ismagilov, Jesus Rodriguez Manzano, Mikhail Karymov, David A. Selck, Stefano Begolo, Erik B. Jue, Dmitriy V. Zhukov
  • DEVICES AND METHODS FOR DIRECT VISUAL DETECTION AND READOUT OF SINGLE NUCLEIC ACID MOLECULES
    Publication number: 20180321137
    Abstract: The present invention relates to methods, computer readable medium and systems for detecting and counting single nucleic acid molecules confined in nanoliter volumes using an unmodified camera, such as a cell phone camera. In particular, it identifies colorimetric amplification-indicator dyes that are compatible with the spectral sensitivity of standard mobile phones. The invention further provides an optimal ratiometric image-process for a selected dye to achieve a readout that is robust to lighting conditions and camera hardware and provides unambiguous quantitative results, even for colorblind users.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 8, 2018
    Inventors: Rustem F. ISMAGILOV, Jesus Rodriguez MANZANO, Mikhail KARYMOV, David A. SELCK, Stefano BEGOLO, Erik B. JUE, Dmitriy V. ZHUKOV
  • MICROFLUIDIC MEASUREMENTS OF THE RESPONSE OF AN ORGANISM TO A DRUG
    Publication number: 20180274020
    Abstract: Disclosed herein are methods and devices for rapid assessment of whether a microorganism present in a sample is susceptible or resistant to a treatment.
    Type: Application
    Filed: November 5, 2015
    Publication date: September 27, 2018
    Inventors: Rustem F. ISMAGILOV, Eugenia KHOROSHEVA, Travis S. SCHLAPPI, Matthew S. CURTIS, Nathan G. SCHOEPP, Hedia MAAMAR, Feng SHEN, Erik B. JUE
  • THE PUMPING LID: DEVICES AND METHODS FOR PROGRAMMABLE GENERATION OF POSITIVE AND NEGATIVE PRESSURES
    Publication number: 20170225161
    Abstract: Provided herein are devices and methods for generating positive and negative pressures. The devices and methods are suited for the generation of pressures; in particular, the pressures generated can be useful for controlling the flow of fluids, such as in fluidic device.
    Type: Application
    Filed: August 14, 2015
    Publication date: August 10, 2017
    Inventors: Stefano BEGOLO, Dmitriy V. ZHUKOV, Daan WITTERS, Erik B. JUE, Rustem F. ISMAGILOV