Patents by Inventor Erik Bey

Erik Bey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PH-sensitive compositions for delivery of beta lapachone and methods of use
    Patent number: 9631041
    Abstract: Disclosed herein are compounds comprising a polymer conjugated with a pH-sensitive prodrug of beta-lapachone, wherein the compound is capable of forming a micelle, and wherein the pH-sensitive prodrug comprises a pH-sensitive linker selected from the group consisting of: an aryl imine and an aliphatic imine. Also provided are micelles comprised of such polymer-prodrug conjugates. Further provided are methods for treating cancer with the micelles.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: April 25, 2017
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Jinming Gao, David Boothman, Yinjian Zhou, Erik Bey
  • Methods of treating cancer comprising targeting NQO1
    Patent number: 9469878
    Abstract: Disclosed herein are methods for determining whether an individual with cancer is suitable for a treatment with an NQO1 bioactivatable drug, predicting responsiveness of an individual with cancer to a treatment with an NQO1 bioactivatable drug, and treating an individual with cancer with an NQO1 bioactivatable drug composition.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: October 18, 2016
    Assignee: The Board of Regents of the University of Texas System
    Inventors: David Boothman, Jinming Gao, Erik Bey, Ying Dong
  • pH-SENSITIVE COMPOSITIONS FOR DELIVERY OF BETA LAPACHONE AND METHODS OF USE
    Publication number: 20130331426
    Abstract: Disclosed herein are compounds comprising a polymer conjugated with a pH-sensitive prodrug of beta-lapachone, wherein the compound is capable of forming a micelle, and wherein the pH-sensitive prodrug comprises a pH-sensitive linker selected from the group consisting of: an aryl imine and an aliphatic imine. Also provided are micelles comprised of such polymer-prodrug conjugates. Further provided are methods for treating cancer with the micelles.
    Type: Application
    Filed: August 11, 2011
    Publication date: December 12, 2013
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Jinming GAO, David Boothman, Yinjian Zhou, Erik Bey