Abstract: A breathing apparatus has a first delivery device for adding a volume of a substance to a gas flow, the delivery device having a gas inlet and a gas outlet. A unit monitors a presence of the substance in a gas downstream the delivery device using a first sensor unit at the gas outlet that provides a first measurement value based on an acoustic property of a gas in a first conduit. A second sensor unit at the gas inlet provides a second measurement value based on an acoustic property of a gas present in the second conduit. A control unit determines the presence of the substance based on the first measurement value or based on a comparison of the first measurement value and the second measurement value.

Abstract: A ventilation system provides patient-triggered support ventilation to a spontaneously breathing patient during ongoing high frequency ventilation (HFV), and has a pneumatic unit operated by a control computer for delivery of breathing gas in response to an effort to breathe by the patient, and an oscillator for superimposing high frequency oscillation onto the breathing gas. The system further includes a bioelectric sensor that measures a bioelectric signal indicative of the patient's efforts to breathe, and the control computer controls the delivery of breathing gas in response to the patient's effort to breathe, based on this bioelectric signal. The ventilation system is hence designed for neurally triggered support ventilation during ongoing HFV, which makes the trigger mechanism of the ventilation system more precise and robust compared to known trigger mechanisms of HFV ventilation systems.

Abstract: A pump arrangement comprising two pump units, each pump unit comprising a pumping cylinder, a reciprocally movable pumping piston, said pumping piston delimiting a pumping chamber in the pumping cylinder in communication with a pump port for fluids, an actuator connected to the pumping piston, and determining a value dependent on the position of the pumping piston in the pumping cylinder, said pump arrangement further comprises a inlet and delivery valves connecting the pump port of each pump unit to a source line and a delivery line for pumped fluids, wherein the pump arrangement comprises at least one regulating unit the flow of the pumped fluids based on the value dependent on the positions of the pumping pistons in the pump units. Also a system comprising such a pump arrangement and a method for pumping fluids in said pump arrangement.

Abstract: A ventilation system for providing patient-triggered support ventilation to a spontaneously breathing patient during ongoing HFV ventilation has a pneumatic unit for delivery of breathing gas to the patient in response to an effort to breathe by the patient, a control computer for controlling the delivery of breathing gas by said pneumatic unit, and an oscillator for superimposing high frequency oscillation onto the breathing gas. The system further includes a bioelectric sensor that measures a bioelectric signal indicative of the patient's efforts to breathe, and the control computer is configured to control the delivery of breathing gas in response to the patient's effort to breathe, based on this bioelectric signal.

Abstract: A breathing apparatus has a first delivery device for adding a volume of a substance to a gas flow, the delivery device having a gas inlet and a gas outlet. A unit monitors a presence of the substance in a gas downstream the delivery device using a first sensor unit at the gas outlet that provides a first measurement value based on an acoustic property of a gas in a first conduit. A second sensor unit at the gas inlet provides a second measurement value based on an acoustic property of a gas present in the second conduit. A control unit determines the presence of the substance based on the first measurement value or based on a comparison of the first measurement value and the second measurement value.

Abstract: A breathing apparatus has an expiratory flow sensor unit, an expiratory pressure sensor unit, an expiratory pressure regulator, and an expiratory control unit operatively connected to the expiratory pressure sensor unit for a feedback control of an expiratory pressure during an expiratory phase of a breathing cycle. The expiratory control unit is adapted to provide a real time target pressure value during the expiratory phase to the expiratory pressure regulator for adjusting a desired positive end expiratory pressure (PEEP) level (PEEPset) based on an inspiratory tidal volume of an inspiratory phase of the same breathing cycle and a currently accumulated expiratory tidal volume measured by the expiratory flow sensor unit. In this manner advantageous regulation of PEEP with minimized work of breathing is obtained.

Abstract: A breathing apparatus has a first delivery device for adding a volume of a substance to a gas flow, the delivery device having a gas inlet and a gas outlet. A unit monitors a presence of the substance in a gas downstream the delivery device using a first sensor unit at the gas outlet that provides a first measurement value based on an acoustic property of a gas in a first conduit. A second sensor unit at the gas inlet provides a second measurement value based on an acoustic property of a gas present in the second conduit. A control unit determines the presence of the substance based on the first measurement value or based on a comparison of the first measurement value and the second measurement value.

Abstract: According to the present invention a flow meter is provided for measuring a fluid, comprising a measuring tube with a measuring piston movably arranged in said measuring tube, and elements for changing the direction of movement of the measuring piston in said measuring tube, wherein said measuring piston, when measuring, is designed to be moved in said measuring tube under the influence of said fluid. Sensor elements detect movement of the piston and the direction of movement in said measuring tube, and sensor elements detect when the piston is situated in at least one of its reversing areas before the measuring piston has reached the extreme point of the reversing area, so as to afford a substantially continuous flow detection for said fluid.

Abstract: A device is directly or indirectly connectable to a patient for determining a volume related to the lungs of the patient. The device has an inspiration part through which a breathing gas passes towards the patient, and an expiration part through which the breathing gas passes away from the patient. The inspiration part has a mouthpiece for introducing a change of the gas composition in the breathing gas. The device implements a method for determining the volume with a detector being arranged in the expiration part that measures a measuring parameter which is dependent on the change in the gas composition, and with a calculation unit connected to the detector unit that determines the variation in the measuring parameter, and determines the volume from the determined variation.

Abstract: According to the present invention a flow meter is provided for measuring a fluid, comprising a measuring tube with a measuring piston movably arranged in said measuring tube, and elements for changing the direction of movement of the measuring piston in said measuring tube, wherein said measuring piston, when measuring, is designed to be moved in said measuring tube under the influence of said fluid. Sensor elements detect movement of the piston and the direction of movement in said measuring tube, and sensor elements detect when the piston is situated in at least one of its reversing areas before the measuring piston has reached the extreme point of the reversing area, so as to afford a substantially continuous flow detection for said fluid.

Abstract: An apparatus for determining the proportion of gases in a gas mixture, has a measurement chamber having a chamber defining structure, a gas inlet and a gas outlet, an ultrasound source and an ultrasound detector mounted such that the ultrasound source is capable of transmitting ultrasound through the chamber to the ultrasound detector; a temperature sensor mounted such that the sensor is capable of sensing the temperature in the chamber. The chamber defining structure is adapted to amplify thermal exchange with a gas content in the chamber so as to suppress a temperature change in the chamber.

Abstract: A breathing apparatus has a first delivery device for adding a volume of a substance to a gas flow, the delivery device having a gas inlet and a gas outlet. A unit monitors a presence of the substance in a gas downstream the delivery device using a first sensor unit at the gas outlet that provides a first measurement value based on an acoustic property of a gas in a first conduit. A second sensor unit at the gas inlet provides a second measurement value based on an acoustic property of a gas present in the second conduit. A control unit determines the presence of the substance based on the first measurement value or based on a comparison of the first measurement value and the second measurement value.

Abstract: A breathing apparatus has an expiratory flow sensor unit, an expiratory pressure sensor unit, an expiratory pressure regulator, and an expiratory control unit operatively connected to the expiratory pressure sensor unit for a feedback control of an expiratory pressure during an expiratory phase of a breathing cycle. The expiratory control unit is adapted to provide a real time target pressure value during the expiratory phase to the expiratory pressure regulator for adjusting a desired positive end expiratory pressure (PEEP) level (PEEPset) based on an inspiratory tidal volume of an inspiratory phase of the same breathing cycle and a currently accumulated expiratory tidal volume measured by the expiratory flow sensor unit. In this manner advantageous regulation of PEEP with minimized work of breathing is obtained.

Abstract: The present invention relates to a multipurpose flow module comprising flow plates and/or heat exchanger plates stacked together, which flow plate having a flow channel and one or more connection ports. To each flow plate or heat exchanger plate one or more barrier plates may be attached. The present invention further relates to a method for extraction, for reaction, for mixing, or combinations thereof in the multipurpose flow module, and to uses of the multipurpose flow module.

Abstract: The present invention relates to a pump arrangement comprising two pump units, each pump unit comprising a pumping cylinder, a reciprocally movable pumping piston, said pumping piston delimiting a pumping chamber in the pumping cylinder in communication with a pump port for fluids, an actuator connected to the pumping piston, and means for determining a value dependent on the position of the pumping piston in the pumping cylinder, said pump arrangement further comprises a first set of valves connecting the pump port of each pump unit to a source line and a delivery line for pumped fluids, wherein the pump arrangement comprises means for regulating the flow of the pumped fluids based on the value dependent on the positions of the pumping pistons in the pump units. The present invention further relates to a system comprising such a pump arrangement and a method for pumping fluids in said pump arrangement.

Abstract: An apparatus for determining the proportion of gases in a gas mixture, has a measurement chamber having a chamber defining structure, a gas inlet and a gas outlet, an ultrasound source and an ultrasound detector mounted such that the ultrasound source is capable of transmitting ultrasound through the chamber to the ultrasound detector; a temperature sensor mounted such that the sensor is capable of sensing the temperature in the chamber. The chamber defining structure is adapted to amplify thermal exchange with a gas content in the chamber so as to suppress a temperature change in the chamber.

Abstract: An apparatus for determining the proportion of gases in a gas mixture, has a measurement chamber having a chamber defining structure, a gas inlet and a gas outlet, an ultrasound source and an ultrasound detector mounted such that the ultrasound source is capable of transmitting ultrasound through the chamber to the ultrasound detector; a temperature sensor mounted such that the sensor is capable of sensing the temperature in the chamber. The chamber defining structure is adapted to amplify thermal exchange with a gas content in the chamber so as to suppress a temperature change in the chamber.

Abstract: An apparatus for determining the proportion of gases in a gas mixture, has a measurement chamber having a chamber defining structure, a gas inlet and a gas outlet, an ultrasound source and an ultrasound detector mounted such that the ultrasound source is capable of transmitting ultrasound through the chamber to the ultrasound detector; a temperature sensor mounted such that the sensor is capable of sensing the temperature in the chamber. The chamber defining structure is adapted to amplify thermal exchange with a gas content in the chamber so as to suppress a temperature change in the chamber.

Abstract: The present invention relates to a multipurpose flow module comprising flow plates and/or heat exchanger plates stacked together, which flow plate having a flow channel and one or more connection ports. To each flow plate or heat exchanger plate one or more barrier plates may be attached. The present invention further relates to a method for extraction, for reaction, for mixing, or combinations thereof in the multipurpose flow module, and to uses of the multipurpose flow module.

Abstract: A device is directly or indirectly connectable to a patient for determining a volume related to the lungs of the patient. The device has an inspiration part through which a breathing gas passes towards the patient, and an expiration part through which the breathing gas passes away from the patient. The inspiration part has a mouthpiece for introducing a change of the gas composition in the breathing gas. The device implements a method for determining the volume with a detector being arranged in the expiration part that measures a measuring parameter which is dependent on the change in the gas composition, and with a calculation unit connected to the detector unit that determines the variation in the measuring parameter, and determines the volume from the determined variation.