Abstract: System and methods for diagnosing traumatic brain injury in a patient using a virtual reality system. One example embodiment provides a system comprising a virtual reality system and at least one electronic processor. The virtual reality system is comprised of a headset and at least one hand controller configured to receive response input from the patient and generate a patient test response based at least in part on patient input. The at least one electronic processor is configured to select a test-response profile from a plurality of test-response profiles, transmit tests associated with the test-response profile to the headset, receive the patient test response, determine the correctness and timing of the patient test response, create at least one test-response record, and determine, based on comparison of the at least one test-response record to at least one test-response profile, a diagnosis of brain injury for the patient.