Abstract: A balloon comprising: a center portion having a proximal end, a distal end opposite the proximal end, and a length between the proximal end and the distal end. The center portion comprises: a first nominal diameter and a first radial modulus at the proximal end; a second nominal diameter and a second radial modulus at the distal end; further wherein, the first nominal diameter is equal to the second nominal diameter, such that, when the balloon is inflated to a nominal pressure, the center portion has a constant diameter over the length; and further wherein, the first radial modulus is smaller than the second radial modulus, such that, when the balloon is inflated above a nominal pressure, the center portion adopts a tapered shape in which the proximal end has a first stretched diameter and the distal end has a second stretched diameter, the first stretched diameter being larger than the second stretched diameter.

Abstract: A balloon comprising: a center portion having a proximal end, a distal end opposite the proximal end, and a length between the proximal end and the distal end. The center portion comprises: a first nominal diameter and a first radial modulus at the proximal end; a second nominal diameter and a second radial modulus at the distal end; further wherein, the first nominal diameter is equal to the second nominal diameter, such that, when the balloon is inflated to a nominal pressure, the center portion has a constant diameter over the length; and further wherein, the first radial modulus is smaller than the second radial modulus, such that, when the balloon is inflated above a nominal pressure, the center portion adopts a tapered shape in which the proximal end has a first stretched diameter and the distal end has a second stretched diameter, the first stretched diameter being larger than the second stretched diameter.

Abstract: An expandable stent for implantation in a body lumen, such as an artery, is disclosed. The stent consists of a plurality of radially expandable cylindrical rings generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting links placed so that the stent is flexible in the longitudinal direction. The link pattern is optimized to enhance longitudinal flexibility and high longitudinal strength compression of the stent.

Abstract: An expandable stent for implantation in a body lumen, such as an artery, is disclosed. The stent consists of a plurality of radially expandable cylindrical rings generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting links placed so that the stent is flexible in the longitudinal direction. The link pattern is optimized to enhance longitudinal flexibility and high longitudinal strength compression of the stent.

Abstract: A balloon comprising: a center portion having a proximal end, a distal end opposite the proximal end, and a length between the proximal end and the distal end. The center portion comprises: a first nominal diameter and a first radial modulus at the proximal end; a second nominal diameter and a second radial modulus at the distal end; further wherein, the first nominal diameter is equal to the second nominal diameter, such that, when the balloon is inflated to a nominal pressure, the center portion has a constant diameter over the length; and further wherein, the first radial modulus is smaller than the second radial modulus, such that, when the balloon is inflated above a nominal pressure, the center portion adopts a tapered shape in which the proximal end has a first stretched diameter and the distal end has a second stretched diameter, the first stretched diameter being larger than the second stretched diameter.

Abstract: An expandable stent for implantation in a body lumen, such as an artery, is disclosed. The stent consists of a plurality of radially expandable cylindrical rings generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting links placed so that the stent is flexible in the longitudinal direction. The link pattern is optimized to enhance longitudinal flexibility and high longitudinal strength compression of the stent.

Abstract: A balloon comprising: a center portion having a proximal end, a distal end opposite the proximal end, and a length between the proximal end and the distal end. The center portion comprises: a first nominal diameter and a first radial modulus at the proximal end; a second nominal diameter and a second radial modulus at the distal end; further wherein, the first nominal diameter is equal to the second nominal diameter, such that, when the balloon is inflated to a nominal pressure, the center portion has a constant diameter over the length; and further wherein, the first radial modulus is smaller than the second radial modulus, such that, when the balloon is inflated above a nominal pressure, the center portion adopts a tapered shape in which the proximal end has a first stretched diameter and the distal end has a second stretched diameter, the first stretched diameter being larger than the second stretched diameter.

Abstract: Medical devices and methods for forming an arteriovenous (AV) fistula include a stent having an arterial tubular portion and vein supporting tongue connected by a pre-shaped connector and a venous frustoconical stent having a distal end for maintaining a take-off angle for the venous portion of the AV fistula. Also disclosed is an angled balloon for assisting with the formation of the AV fistula. The medical devices disclosed herein support an AV fistula formation having a desired take off angle of about 30 degrees, or between about 15 and 45 degrees.

Abstract: A medical device includes a curved tubular body configured for being used as an extravascular device to support vein maturation following the formation of an arteriovenous fistula. The tubular body is curved. The tubular body has an entrance angle of less than about 40 degrees to improve blood flow from the artery into the vein. And the tubular body includes a cuff or edge at the proximal end to stabilize the tubular body at the fistula.

Abstract: Medical devices and methods for forming an arteriovenous (AV) fistula include a stent having an arterial tubular portion and vein supporting tongue connected by a pre-shaped connector and a venous frustoconical stent having a distal end for maintaining a take-off angle for the venous portion of the AV fistula. Also disclosed is an angled balloon for assisting with the formation of the AV fistula. The medical devices disclosed herein support an AV fistula formation having a desired take off angle of about 30 degrees, or between about 15 and 45 degrees.

Abstract: Endoprosthesis for delivery in a body lumen is provided. The endoprosthesis includes an annular element defined by a set of interconnected strut members, each strut member including a first end and a second end. The first end of selected pairs of circumferentially-adjacent strut members of the annular element are interconnected to define apices proximate a first longitudinal side of the annular element and the second end of selected pairs circumferentially-adjacent strut members are interconnected to define apices proximate a second longitudinal side of the annular element. At least one of the selected pairs of circumferentially-adjacent strut members has a modulator disposed proximate the apex defined there between, the modulator having a first mode to allow expansion of the annular element from an unexpanded configuration toward an expanded configuration and a second mode to resist contraction of the annular element from the expanded configuration toward the unexpanded configuration.

Abstract: Endoprosthesis for delivery in a body lumen is provided. The endoprosthesis includes an annular element defined by a set of interconnected strut members, each strut member including a first end and a second end. The first end of selected pairs of circumferentially-adjacent strut members of the annular element are interconnected to define apices proximate a first longitudinal side of the annular element and the second end of selected pairs circumferentially-adjacent strut members are interconnected to define apices proximate a second longitudinal side of the annular element. At least one of the selected pairs of circumferentially-adjacent strut members has a modulator disposed proximate the apex defined there between, the modulator having a first mode to allow expansion of the annular element from an unexpanded configuration toward an expanded configuration and a second mode to resist contraction of the annular element from the expanded configuration toward the unexpanded configuration.

Abstract: Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration.

Abstract: Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration.

Abstract: Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration.

Abstract: Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration.

Abstract: The invention is directed to a delivery system for delivering a medical device. The delivery system includes an inner member having a proximal end and a distal end. The inner member defines a longitudinal axis between the proximal end and the distal end. A tip is formed at the distal end of the inner member. A bumper is freely disposed on the inner member. The bumper has a proximal end and a distal end. A seat is defined between the tip and the distal end of the bumper. Additionally, a sheath is disposed about the inner member, the sheath having a proximal end and a distal end. The sheath is movable from a first sheath position substantially covering the seat, and a second sheath position axially offset to expose the seat. The invention also includes a handle in contact with the proximal end of the inner member.

Abstract: Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration.

Abstract: Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration.

Abstract: Endoprosthesis, such as a stent, includes at least one annular element defined by a first set of strut members interconnected to define apices proximate opposite sides of the annular element. The annular element further includes a foot extension extending between at least one pair of circumferentially-adjacent strut members. The foot extension has first and second foot portions extending circumferentially from corresponding ends of the circumferentially-adjacent strut members, and are contoured to provide at least two areas of flexure. The first and second foot portions are joined at a toe portion of the foot extension, and define a circumferentially-directed apex between the pair of circumferentially-adjacent strut members. Preferably, at least one or more additional annular elements, each defined by interconnected strut members, are provided. The annular elements are generally expandable between a delivery configuration and a deployed configuration.