Patents by Inventor Erik Gunther

Erik Gunther has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel proteins and nucleic acids encoding same
    Publication number: 20040043930
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: March 31, 2003
    Publication date: March 4, 2004
    Inventors: David W. Anderson, Patricia Bento, Ferenc Boldog, Catherine Burgess, Stacie Casman, Katarzyna Furtak, Linda Gorman, Bonnie Gould-Rothberg, Erik Gunther, Melvyn Heyes, Li Li, Kimberly Spytek, David Stone, Mei Zhong, Uriel Malyankar, Shlomit Edinger, Meera Patturajan, Mark Rothenberg, Glennda Smithson
  • Proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20040029216
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 9, 2002
    Publication date: February 12, 2004
    Inventors: Muralidhara Padigaru, Li Li, Bryan D. Zerhusen, Stacie J. Casman, Suresh G. Shenoy, Kimberly Spytek, Mei Zhong, Esha A. Gangolli, Catherine E. Burgess, Meera Patturajan, Corine A.M. Vernet, Sarah Taylor, Velizar T. Tchernev, Charles E. Miller, Xiaojia Guo, Ferenc L. Boldog, William M. Grosse, John P. Alsobrook, Valerie L. Gerlach, Shlomit R. Edinger, Mark E. Rothenberg, Karen Ellerman, John MacDougall, Uriel M. Malyankar, Isabelle Millet, John Peyman, Glennda Smithson, Erik Gunther, David Stone
  • Proteins and nucleic acids encoding same
    Publication number: 20040022781
    Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: December 31, 2001
    Publication date: February 5, 2004
    Inventors: Kimberly A. Spytek, Li Li, Adam R. Wolenc, Corine Vernet, Andrew J. Eisen, Xiaohong Liu, Uriel M. Malyankar, Richard A. Shimkets, Velizar Tchernev, Steven K. Spaderna, Linda Gorman, Ramesh Kekuda, Meera Patturajan, Vladimir Y. Gusev, Esha A. Gangolli, Xiaojia (Sasha) Guo, Suresh G. Shenoy, Luca Rastelli, Stacie J. Casman, Ferenc L. Boldog, Catherine E. Burgess, Shlomit R. Edinger, Karen Ellerman, Erik Gunther, Glennda Smithson, Isabelle Millet, John R. MacDougall
  • Novel human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20040024181
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 26, 2001
    Publication date: February 5, 2004
    Inventors: Esha A. Gangolli, Kimberly A. Spytek, Jennifer Gilbert, Stacie Casman, Angela Blalock, Li Li, Corine Vernet, Suresh Shenoy, Vishnu S. Mishra, Katarzyna Furtak, Valerie L. Gerlach, Shlomit Edinger, Uriel Malyanker, David Stone, Isabelle Millet, Glennda Smithson, Erik Gunther, Karen Ellerman, Muralidhara Padigaru, Raymond J. Taupier, David W. Anderson
  • Novel antibodies that bind to antigenic polypeptides, nucleic acids encoding the antigens, and methods of use
    Publication number: 20040018594
    Abstract: Disclosed herein are nucleic acid sequences that encode polypeptides. Also disclosed are antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids, polypeptides, or antibodies, or fragments thereof.
    Type: Application
    Filed: May 1, 2002
    Publication date: January 29, 2004
    Inventors: John P. Alsobrook, David W. Anderson, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Andrei Chapoval, Shlomit R. Edinger, Valerie Gerlach, Linda Gorman, Erik Gunther, Xiaojia Sasha Guo, Ramesh Kekuda, Denise M. Lepley, Li Li, Xiaohong Liu, Uriel M. Malyankar, Charles E. Miller, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Daniel K. Rieger, Suresh G. Shenoy, Richard A. Shimkets, Kimberly A. Spytek, Raymond J. Taupier, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen
  • Novel polynucleotides, polypeptides encoded thereby and methods of use thereof
    Publication number: 20040014173
    Abstract: The present invention provides novel polypeptides, termed SECX polypeptides, as well as polynucleotides encoding SECX polypeptides and antibodies that immunospecifically bind to SECX or a derivative, variant, mutant, or fragment of the SECX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the SECX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to others uses.
    Type: Application
    Filed: March 10, 2003
    Publication date: January 22, 2004
    Inventors: David W. Anderson, Ferenc L. Boldog, Stacie J. Casman, Shlomit R. Edinger, Karen Ellerman, Elma R. Fernandes, Erik Gunther, Martin D. Leach, John R. MacDougall, Muralidhara Padigaru, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek
  • Proteins, polynucleotides ecoding them and methods of using the same
    Publication number: 20040005558
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 18, 2002
    Publication date: January 8, 2004
    Inventors: David W. Anderson, Catherine E. Burgess, Stacie J. Casman, Steven D. Colman, Shlomit R. Edinger, Karen Ellerman, Valerie Gerlach, Erik Gunther, Ramesh Kekuda, John R. MacDougall, Fuad Mehraban, Meera Patturajan, Mark Rothenberg, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Corine A.M. Vernet, Bryan D. Zerhusen
  • Novel GPCR-like proteins and nucleic acids encoding same
    Publication number: 20040005656
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 16, 2001
    Publication date: January 8, 2004
    Inventors: Ramesh Kekuda, Kimberly A. Spytek, Stacie J. Casman, Bryan D. Zerhusen, Li Li, Velizar T. Tchernev, Steven D. Colman, Robert A. Ballinger, Muralidhara Padigaru, Adam R. Wolenc, Suresh G. Shenoy, Shlomit R. Edinger, Valerie Gerlach, Esha A. Gangolli, John R. MacDougall, Glennda Smithson, John A. Peyman, David J. Stone, Erik Gunther, Karen Ellerman, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess
  • Proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030236389
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 14, 2001
    Publication date: December 25, 2003
    Inventors: Richard A. Shimkets, Steven D. Colman, Kimberly A. Spytek, Robert A. Ballinger, Xiaojia (Sasha) Guo, Velizar T. Tchernev, Suresh G. Shenoy, Li Li, Karen Ellerman, Bryan D. Zerhusen, Meera Patturajan, Stacie J. Casman, Ferenc Boldog, Vladimir Y. Gusev, Catherine E. Burgess, Shlomit R. Edinger, Esha A. Gangolli, Uriel M. Malyankar, Erik Gunther, Glennda Smithson, Isabelle Millet, Valerie Gerlach
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030232332
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 18, 2001
    Publication date: December 18, 2003
    Inventors: Muralidhara Padigaru, Ramesh Kekuda, Li Li, Robert A. Ballinger, Stacie J. Casman, Kimberly A. Spytek, Steven D. Colman, Corine A.M. Vernet, Suresh G. Shenoy, Vladimir Y. Gusev, Uriel M. Malyankar, Shlomit R. Edinger, Valerie Gerlach, Glennda Smithson, David J. Stone, Paul Sciore, John R. MacDougall, Erik Gunther, John A. Peyman, Karen Ellerman, Isabelle Millet, Velizar T. Tchernev, David W. Anderson, Adam R. Wolenc
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030232331
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 4, 2001
    Publication date: December 18, 2003
    Inventors: Stacie J. Casman, Muralidhara Padigaru, Catherine E. Burgess, Richard A. Shimkets, Kimberly A. Spytek, Jennifer A. Gilbert, Jane E. Mayotte, Jason C. Baumgartner, Vishnu Mishra, Corine A.M. Vernet, Kevin S. Dickinson, Robert A. Ballinger, Adam R. Wolenc, Shlomit R. Edinger, John R. MacDougall, Glennda Smithson, Karen Ellerman, David J. Stone, Erik Gunther, Valerie Gerlach
  • Novel human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20030228301
    Abstract: Disclosed are novel polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: October 24, 2001
    Publication date: December 11, 2003
    Inventors: Li Li, Katarzyna Furtak, Amanda Perna, Meera Patturajan, Richard A. Shimkets, Xiaojia Sasha Guo, Stacie J. Casman, Catherine E. Burgess, Uriel M. Malyankar, Velizar T. Tchernev, Corine A. Vernet, Kimberly A. Spytek, Michele Agee, Luca Rastelli, Suresh G. Shenoy, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Valerie Gerlach, Schlomit R. Edinger, John R. MacDougall, John A. Peyman, Erik Gunther, David J. Stone, Karen Ellerman, Esha A. Gangolli
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030216545
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 27, 2001
    Publication date: November 20, 2003
    Inventors: Kimberly A. Spytek, Stacie Casman, Muralidhara Padigaru, Kevin S. Dickson, Corine Vernet, Steven K. Spaderna, Suresh G. Shenoy, Valerie Gerlach, Karen Ellerman, Shlomit Edinger, John R. MacDougall, Glennda Smithson, Li Li, Uriel M. Malyankar, Sarah Taylor, Erik Gunther, Velizar T. Tchernev
  • Proteins and nucleic acids encoding same
    Publication number: 20030212256
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 16, 2001
    Publication date: November 13, 2003
    Inventors: Shlomit R. Edinger, Valerie Gerlach, John R. MacDougall, Uriel M. Malyankar, Glennda Smithson, Isabelle Millet, John A. Peyman, David J. Stone, Erik Gunther, Karen Ellerman, Richard A. Shimkets, Muralidhara Padigaru, Xiaojia Guo, Meera Patturajan, Raymond J. Taupier, Catherine E. Burgess, Bryan D. Zerhusen, Ramesh Kekuda, Kimberly A. Spytek, Esha A. Gangolli, Elma R. Fernandes, Linda Gorman
  • Novel polypeptides and nucleic acids encoding same
    Publication number: 20030207801
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 22, 2001
    Publication date: November 6, 2003
    Inventors: Valerie Gerlach, John R. MacDougall, Isabelle Millet, Erik Gunther, Karen Ellerman, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Corine A. M. Vernet, Suresh G. Shenoy, Kimberly Ann Spytek, Vishnu S. Mishra, Muralidhara Padigaru
  • Proteins and nucleic acids encoding same
    Publication number: 20030203843
    Abstract: Disclosed are polypeptides and nucleic acids encoding same. Also disclosed are vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same.
    Type: Application
    Filed: April 11, 2002
    Publication date: October 30, 2003
    Inventors: Carol E. A. Pena, Xiaojia (Sasha) Guo, Richard A. Shimkets, Muralidhara Padigaru, Ramesh Kekuda, Kimberly A. Spytek, Fuad Mehraban, James Newman Topper, Uriel M. Malyankar, Scott Michael Wasserman, Shlomit R. Edinger, Glennda Smithson, Erik Gunther, Laszlo Komuves
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030198955
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 19, 2001
    Publication date: October 23, 2003
    Inventors: Li Li, Muralidhara Padigaru, Robert A. Ballinger, Ramesh Kekuda, Steven D. Colman, Kimberly A. Spytek, Stacie J. Casman, Shlomit R. Edinger, Valerie Gerlach, Paul Sciore, Glennda Smithson, John A. Peyman, John R. MacDougall, David J. Stone, Corine A.M. Vernet, Suresh G. Shenoy, Erik Gunther, Isabelle Millet, Velizar T. Tchernev, David W. Anderson, Vladimir Y. Gusev, Uriel M. Malyankar, Haihong Zhong, Karen Ellerman, Adam R. Wolenc
  • Novel proteins and nucleic acids encoding same
    Publication number: 20030190715
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 12, 2001
    Publication date: October 9, 2003
    Inventors: William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Vishnu Mishra, Ramesh Kekuda, Li Li, Muralidhara Padigaru, Richard A. Shimkets, Bryan D. Zerhusen, Kimberly A. Spytek, Shlomit R. Edinger, Valerie Gerlach, John R. MacDougall, Isabelle Millet, David J. Stone, Erik Gunther, Karen Ellerman
  • Proteins and nucleic acids encoding same
    Publication number: 20030170630
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 21, 2001
    Publication date: September 11, 2003
    Inventors: John P. Alsobrook, Velizar T. Tchernev, Xiaohong Liu, Kimberly A. Spytek, Bryan D. Zerhusen, Meera Patturajan, Denise M. Lepley, Catherine E. Burgess, Richard A. Shimkets, William M. Grosse, Edward S. Szekeres, Corine A.M. Vernet, Li Li, Stacie J. Casman, Ference L. Boldog, Linda Gorman, Esha A. Gangolli, Elma R. Fernandes, Danier K. Rieger, Shlomit R. Edinger, Erik Gunther, Isabelle Millet, Paul Sciore, Karen Ellerman, John R. MacDougall, Glennda Smithson
  • Novel polynucleotides and polypeptides encoded thereby
    Publication number: 20030170838
    Abstract: Disclosed herein are nucleic acid sequences that encode Wnt, zinc transporter, mitsugumin29, slit-3, LRR/GPCR, major histocompatability complex enhancer protein MAD3, interleukin 9, 5-hydroxytryptamine receptor, and thioredoxin related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 17, 2001
    Publication date: September 11, 2003
    Inventors: Vishnu S. Mishra, Kimberly Ann Spytek, Raymond J. Taupier, Corine A. Vernet, Steven D. Colman, Linda Gorman, Velizar T. Tchernev, Uriel M. Malyankar, Suresh Shenoy, Muralidhara Padigaru, Valerie L. Gerlach, John R. MacDougall, Glennda Smithson, Isabelle Millet, John Peyman, David Stone, Erik Gunther, Karen Ellerman, Li Li, Luca Rastelli, Bryan Zerhusen