Patents by Inventor Erik Hack

Erik Hack has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTAGONISTS OF THE COMPLEMENT SYSTEM FOR USE IN METHODS OF TREATING PARAPROTEINEMIC NEUROPATHIES
    Publication number: 20250066460
    Abstract: The present invention relates to a method of treating a paraproteinemic neuropathy in a subject by administering to the subject an antagonist of the complement system. The antagonist inhibits the complement system upstream of complement factor C5. More specifically, the antagonist may be an antibody or an antigen-binding fragment thereof that blocks or inhibits the complement system by inhibiting the C2b domain of complement factor C2. The paraproteinemic neuropathies that may be treated include, in particular, multifocal motor neuropathy (MMN), chronic inflammatory demyelinating polyneuropathy (CIDP), and Guillain-Barre syndrome (GBS).
    Type: Application
    Filed: May 21, 2020
    Publication date: February 27, 2025
    Inventors: Christophe BLANCHETOT, Kevin BUDDING, Erik HACK, Karen SILENCE, Inge VAN DE WALLE, Ludo VAN DER POL, Peter BOROSS
  • USE OF ANTI-FACTOR XI ANTIBODIES FOR PREVENTION OF THROMBUS FORMATION
    Publication number: 20180118850
    Abstract: The present invention relates to binding molecules such as antibodies that specifically bind plasma coagulation factor XI and that inhibit factor XI activation and/or activity. The factor XI-binding molecules of the invention maybe sued in methods for preventing or treating diseases, disorders and/or condition that are mediated by factor XI activation and/or wherein inhibition of factor XI has a beneficial effect.
    Type: Application
    Filed: December 18, 2017
    Publication date: May 3, 2018
    Applicant: Prothix B.V.
    Inventor: Erik HACK
  • USE OF ANTI-FACTOR XI ANTIBODIES FOR PREVENTION OF THROMBUS FORMATION
    Publication number: 20140194600
    Abstract: The present invention relates to binding molecules such as antibodies that specifically bind plasma coagulation factor XI and that inhibit factor XI activation and/or activity. The factor XI-binding molecules of the invention may used in methods for preventing or treating diseases, disorders and/or conditions that are mediated by factor XI activation and/or wherein inhibition of factor XI has a beneficial effect.
    Type: Application
    Filed: September 24, 2013
    Publication date: July 10, 2014
    Applicant: Prothix B.V.
    Inventor: Erik HACK
  • Use of anti-factor XI antibodies for prevention of thrombus formation
    Patent number: 8568724
    Abstract: The present invention relates to binding molecules such as antibodies that specifically bind plasma coagulation factor XI and that inhibit factor XI activation and/or activity. The factor XI-binding molecules of the invention may used in methods for preventing or treating diseases, disorders and/or conditions that are mediated by factor XI activation and/or wherein inhibition of factor XI has a beneficial effect.
    Type: Grant
    Filed: June 19, 2012
    Date of Patent: October 29, 2013
    Inventor: Erik Hack
  • USE OF ANTI-FACTOR XI ANTIBODIES FOR PREVENTION OF THROMBUS FORMATION
    Publication number: 20120259097
    Abstract: The present invention relates to binding molecules such as antibodies that specifically bind plasma coagulation factor XI and that inhibit factor XI activation and/or activity. The factor XI-binding molecules of the invention may used in methods for preventing or treating diseases, disorders and/or conditions that are mediated by factor XI activation and/or wherein inhibition of factor XI has a beneficial effect.
    Type: Application
    Filed: June 19, 2012
    Publication date: October 11, 2012
    Applicant: PROTHIX B.V.
    Inventor: Erik HACK
  • USE OF ANTI-FACTOR XI ANTIBODIES FOR PREVENTION OF THROMBUS FORMATION
    Publication number: 20110159006
    Abstract: The present invention relates to binding molecules such as antibodies that specifically bind plasma coagulation factor XI and that inhibit factor XI activation and/or activity. The factor XI-binding molecules of the invention may used in methods for preventing or treating diseases, disorders and/or conditions that are mediated by factor XI activation and/or wherein inhibition of factor XI has a beneficial effect.
    Type: Application
    Filed: June 19, 2009
    Publication date: June 30, 2011
    Inventor: Erik Hack