Abstract: Aspects of the disclosure relate to devices and methods for preparing an existing, implanted prosthetic aortic valve for subsequent prosthetic aortic valve implantation. To prepare the existing valve, a valve preparation device is delivered to the valve and valve leaflets are severed either via mechanical cutting or electrodes so that the leaflets cannot obstruct a blood flow path once a prosthetic valve is subsequently implanted within the valve. Similarly, in alternate embodiments, devices and methods of the disclosure can be used for preparing a native aortic valve for delivery and implantation of a prosthetic valve.

Abstract: An LVP that provides peristaltic pumping to removably couplable administration set tubing assemblies supplying medical infusate. The LVP includes a housing, a drive-train assembly, and a controller. The housing includes an assembly receptacle configured to receive an administration set tubing assembly. The drive-train assembly provides mechanical peristaltic movement within the assembly receptacle. The drive-train assembly includes a stepper motor located within the housing and a camshaft assembly, driven by the stepper motor and at least partially extending into the assembly receptacle. The camshaft assembly includes a unitary camshaft and a plurality of tube engaging members that cooperatively move according to rotation of the unitary camshaft. Further, the controller is located within the housing that controls operation of the stepper motor and the camshaft assembly.

Abstract: Medical device delivery system including a catheter, handle, lock line handle, and lock line. The catheter includes a proximal end portion and a distal end portion. The handle is coupled to the proximal end portion of the catheter. The lock line handle is releasably coupled to the handle and actuatable between a lock position and an unlock position. The lock line includes a first end portion fixedly coupled to the lock line handle, a second end portion releasably coupled to the lock line handle, and an intermediate portion configured to be releasably coupled to the medical implant disposed proximate the distal end portion of the catheter. Actuating the lock line handle from the lock position toward the unlock position increases tension on the lock line, and actuating the lock line handle from the unlock position toward the lock position decreases tension on the lock line.

Abstract: Medical device delivery system including a catheter, handle, lock line handle, and lock line. The catheter includes a proximal end portion and a distal end portion. The handle is coupled to the proximal end portion of the catheter. The lock line handle is releasably coupled to the handle and actuatable between a lock position and an unlock position. The lock line includes a first end portion fixedly coupled to the lock line handle, a second end portion releasably coupled to the lock line handle, and an intermediate portion configured to be releasably coupled to the medical implant disposed proximate the distal end portion of the catheter. Actuating the lock line handle from the lock position toward the unlock position increases tension on the lock line, and actuating the lock line handle from the unlock position toward the lock position decreases tension on the lock line.

Abstract: An LVP that provides peristaltic pumping to removably couplable administration set tubing assemblies supplying medical infusate. The LVP includes a housing, a drive-train assembly, and a controller. The housing includes an assembly receptacle configured to receive an administration set tubing assembly. The drive-train assembly provides mechanical peristaltic movement within the assembly receptacle. The drive-train assembly includes a stepper motor located within the housing and a camshaft assembly, driven by the stepper motor and at least partially extending into the assembly receptacle. The camshaft assembly includes a unitary camshaft and a plurality of tube engaging members that cooperatively move according to rotation of the unitary camshaft. Further, the controller is located within the housing that controls operation of the stepper motor and the camshaft assembly.

Abstract: Medical device delivery system including a catheter, handle, lock line handle, and lock line. The catheter includes a proximal end portion and a distal end portion. The handle is coupled to the proximal end portion of the catheter. The lock line handle is releasably coupled to the handle and actuatable between a lock position and an unlock position. The lock line includes a first end portion fixedly coupled to the lock line handle, a second end portion releasably coupled to the lock line handle, and an intermediate portion configured to be releasably coupled to the medical implant disposed proximate the distal end portion of the catheter. Actuating the lock line handle from the lock position toward the unlock position increases tension on the lock line, and actuating the lock line handle from the unlock position toward the lock position decreases tension on the lock line.

Abstract: Aspects of the disclosure relate to devices and methods for preparing an existing, implanted prosthetic aortic valve for subsequent prosthetic aortic valve implantation. To prepare the existing valve, a valve preparation device is delivered to the valve and valve leaflets are severed either via mechanical cutting or electrodes so that the leaflets cannot obstruct a blood flow path once a prosthetic valve is subsequently implanted within the valve. Similarly, in alternate embodiments, devices and methods of the disclosure can be used for preparing a native aortic valve for delivery and implantation of a prosthetic valve.

Abstract: In various examples, a set screw apparatus includes a set screw including a set screw body. An abutment extends radially outwardly from the set screw body and longitudinally separated from a threaded set screw area of a first length by an unthreaded set screw area of a second length of the set screw body. A block includes a bore. A threaded block area includes a third length, wherein the abutment inhibits movement of the set screw past the threaded block area and removal of the set screw from the bore. The third length is shorter than the second length so that an entirety of the threaded block area can be disposed within the unthreaded set screw area, such that the set screw is freely rotatable within the bore, but retained within the bore, if turned in a first direction with respect to the block.

Abstract: In various examples, a set screw apparatus includes a set screw including a set screw body. An abutment extends radially outwardly from the set screw body and longitudinally separated from a threaded set screw area of a first length by an unthreaded set screw area of a second length of the set screw body. A block includes a bore. A threaded block area includes a third length, wherein the abutment inhibits movement of the set screw past the threaded block area and removal of the set screw from the bore. The third length is shorter than the second length so that an entirety of the threaded block area can be disposed within the unthreaded set screw area, such that the set screw is freely rotatable within the bore, but retained within the bore, if turned in a first direction with respect to the block.

Abstract: In various examples, a set screw apparatus includes a set screw including a set screw body. An abutment extends radially outwardly from the set screw body and longitudinally separated from a threaded set screw area of a first length by an unthreaded set screw area of a second length of the set screw body. A block includes a bore. A threaded block area includes a third length, wherein the abutment inhibits movement of the set screw past the threaded block area and removal of the set screw from the bore. The third length is shorter than the second length so that an entirety of the threaded block area can be disposed within the unthreaded set screw area, such that the set screw is freely rotatable within the bore, but retained within the bore, if turned in a first direction with respect to the block.

Abstract: In various examples, a set screw apparatus includes a set screw including a set screw body. An abutment extends radially outwardly from the set screw body and longitudinally separated from a threaded set screw area of a first length by an unthreaded set screw area of a second length of the set screw body. A block includes a bore. A threaded block area includes a third length, wherein the abutment inhibits movement of the set screw past the threaded block area and removal of the set screw from the bore. The third length is shorter than the second length so that an entirety of the threaded block area can be disposed within the unthreaded set screw area, such that the set screw is freely rotatable within the bore, but retained within the bore, if turned in a first direction with respect to the block.