Abstract: The present invention encompasses TAT peptide binding proteins. Specifically, the invention relates to antibodies that specifically bind to a TAT protein transduction domain. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention for detection, quantification, purification and isolation of TAT protein transduction domain, e.g., a TAT fusion molecule comprising a TAT protein transduction domain, as well as methods of diagnosis and monitoring of HIV and AIDS are also provided herein.

Abstract: The present disclosure provides methods for determining the amount of FXN or FXN fusion protein in a sample, e.g, a tissue sample, by using mass spectrometry.