Patents by Inventor Erik Kuester

Erik Kuester has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphodiesterase 4 inhibitors
    Patent number: 7696198
    Abstract: Selective PDE4 inhibition is achieved by 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds like rolipram and show selectivity with regard to inhibition of other classes of PDEs. The compounds of the present invention are of formula I: wherein R1, R2, and R3 are as defined herein.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: April 13, 2010
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Ashok Tehim, Allen Hopper, Ruiping Liu, Erik Kuester, Robert F. Dunn, Thomas E. Renau
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20090221661
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Application
    Filed: February 20, 2009
    Publication date: September 3, 2009
    Inventors: Allen Hopper, Erik Kuester, Robert Dunn, Richard Conticello
  • PHOSPHODIESTERASE 4 INHIBITORS
    Publication number: 20090118270
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted diarylamine analogs. The compounds of the present invention are of Formulas I-III: wherein A, B, D, E, G, J, K, R1, R2, R3, R4, R11, R12, R13, R14, R21, R22, R23 and R24 are as defined herein.
    Type: Application
    Filed: December 5, 2008
    Publication date: May 7, 2009
    Inventors: Francisco Xavier Talamas, Joan Marie Caroon, Robert Dunn, Allen Hopper, Erik Kuester, Richard Schumacher, Ashok Tehim
  • Phosphodiesterase 4 inhibitors
    Patent number: 7495017
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Grant
    Filed: May 1, 2007
    Date of Patent: February 24, 2009
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Allen Hopper, Erik Kuester, Robert Dunn, Richard Conticello
  • PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED ANILINE AND DIPHENYLAMINE ANALOGS
    Publication number: 20090048255
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 and R4 are as defined herein.
    Type: Application
    Filed: July 17, 2008
    Publication date: February 19, 2009
    Inventors: Richard A. SCHUMACHER, Allen T. HOPPER, Ashok TEHIM, Hans-Jurgen Ernst HESS, Axel UNTERBECK, Erik KUESTER, William Frederick BRUBAKER, JR., Robert F. DUNN
  • Phosphodiesterase 4 inhibitors, including N-substituted aniline and diphenylamine analogs
    Patent number: 7405230
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 and R4 are as defined herein.
    Type: Grant
    Filed: July 21, 2003
    Date of Patent: July 29, 2008
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Richard A. Schumacher, Allen T. Hopper, Ashok Tehim, Hans-Jurgen Ernst Hess, Axel Unterbeck, Erik Kuester, William Frederick Brubaker, Jr., Robert F. Dunn
  • Phosphodiesterase 4 inhibitors
    Publication number: 20070203197
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Application
    Filed: May 1, 2007
    Publication date: August 30, 2007
    Inventors: Allen Hopper, Erik Kuester, Robert Dunn, Richard Conticello
  • Phosphodiesterase 4 inhibitors
    Patent number: 7235579
    Abstract: Selective PDE4 inhibition is achieved by 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds like rolipram and show selectivity with regard to inhibition of other classes of PDEs. The compounds of the present invention are of formula I: wherein R1, R2, and R3 are as defined herein.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: June 26, 2007
    Assignee: Memory Pharmaceuticals Corp.
    Inventors: Ruiping Liu, Mike De Vivo, Hans-Jurgen Ernst Hess, Allen Hopper, Erik Kuester, Ashok Tehim
  • Phosphodiesterase 4 inhibitors
    Patent number: 7226930
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: June 5, 2007
    Assignee: Memory Pharmaceutical Corporation
    Inventors: Allen Hopper, Erik Kuester, Robert Dunn, Richard Conticello
  • Phosphodiesterase 4 inhibitors
    Publication number: 20060154960
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Application
    Filed: October 14, 2005
    Publication date: July 13, 2006
    Inventors: Allen Hopper, Robert Dunn, Erik Kuester, Richard Conticello
  • Phosphodiesterase 4 inhibitors
    Publication number: 20060135535
    Abstract: Selective PDE4 inhibition is achieved by novel compounds, e.g., 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds of the present invention are of formula I: wherein R1, R2, and R3 are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
    Type: Application
    Filed: October 20, 2005
    Publication date: June 22, 2006
    Inventors: Allen Hopper, Robert Dunn, Erik Kuester, Richard Conticello, Ruiping Liu, Ashok Tehim
  • Phosphodiesterase 4 inhibitors, including N-substituted diarylamine analogs
    Publication number: 20050222207
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted diarylamine analogs. The compounds of the present invention are of Formula I: wherein A, B, D, R1, R2, R3 and R4 are as defined herein.
    Type: Application
    Filed: December 10, 2004
    Publication date: October 6, 2005
    Inventors: Richard Schumacher, Allen Hopper, Robert Dunn, Erik Kuester, Ashok Tehim, Thomas Renau, Joan Caroon, Francisco Talamas, Sharada Labadie
  • Phosphodiesterase 4 inhibitors, including N-substituted aniline and diphenylamine analogs
    Publication number: 20050119225
    Abstract: PDE4 inhibition is achieved by novel compounds, e.g., N-substituted aniline and diphenylamine analogs. The compounds of the present invention are of Formula I: wherein R1, R2, R3 and R4 are as defined herein.
    Type: Application
    Filed: July 21, 2003
    Publication date: June 2, 2005
    Applicant: MEMORY PHARMACEUTICALS CORP.
    Inventors: Richard Schumacher, Allen Hopper, Ashok Tehim, Hans-Jurgen Hess, Axel Unterbeck, Erik Kuester, William Brubaker, Robert Dunn
  • Phosphodiesterase 4 inhibitors
    Publication number: 20050026913
    Abstract: Selective PDE4 inhibition is achieved by 4-(substituted-phenyl)-2-pyrrolidinone compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds like rolipram and show selectivity with regard to inhibition of other classes of PDEs. The compounds of the present invention are of formula I: wherein R1, R2, and R3 are as defined herein.
    Type: Application
    Filed: April 16, 2004
    Publication date: February 3, 2005
    Inventors: Ashok Tehim, Allen Hopper, Ruiping Liu, Erik Kuester, Robert Dunn, Thomas Renau
  • Phosphodiesterase 4 inhibitors
    Publication number: 20040229918
    Abstract: Selective PDE4 inhibition is achieved by aryl and heteroaryl pyrazole compounds. The compounds exhibit improved PDE4 inhibition as compared to compounds such as rolipram and show selectivity with regard to inhibition of other classes of PDEs.
    Type: Application
    Filed: April 16, 2004
    Publication date: November 18, 2004
    Inventors: Allen Hopper, Erik Kuester, Robert Dunn, Richard Conticello