Patents by Inventor Erik M. Shapiro

Erik M. Shapiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tantalum Oxide Nanoparticle Contrast Agents
    Publication number: 20220048788
    Abstract: A nanoparticle composition is provided. The nanoparticle composition includes a plurality of nanoparticles, each nanoparticle of the plurality having a core including tantalum oxide, and a covalent coating covalently bound to the core. The covalent coating includes a surface modifier selected from the group consisting of (3-aminopropyl)trimethoxy silane (APTMS), (3-aminopropyl)triethoxy silane (APTES), APTMS-methoxy-poly(ethylene-glycol)-succinimidyl glutarate (APTMS-m-PEG-glutarate), APTES-methoxy-poly(ethylene-glycol)-succinimidyl glutarate (APTES-m-PEG-glutarate), 2-[methoxy (polyethyleneoxy)-9-12-propyl] trimethoxysilane (PEG-Silane), hexadecyltriethoxy silane, and combinations thereof. Methods of synthesizing and using the nanoparticle composition are also provided.
    Type: Application
    Filed: July 6, 2021
    Publication date: February 17, 2022
    Applicant: Board of Trustees of Michigan State University
    Inventors: Shatadru CHAKRAVARTY, Erik M. SHAPIRO
  • Affinity Magnetic Particles For Imaging System
    Publication number: 20210228746
    Abstract: A nanoparticle construct is provided. The nanoparticle construct includes a nanoparticle defining an outer surface, a magnetic nanocrystal carried by the nanoparticle, and a coupling agent extending from the outer surface of the nanoparticle. The coupling agent is configured to couple the nanoparticle construct to a cell.
    Type: Application
    Filed: January 26, 2021
    Publication date: July 29, 2021
    Applicant: Board of Trustees of Michigan State University
    Inventors: Erik M. SHAPIRO, Shatadru CHAKRAVARTY
  • Pulse imaging sequences and methods for T1p-weighted MRI
    Patent number: 6836114
    Abstract: Provided are pulse imaging sequences and methods for 2D multi-slice T1&rgr;-weighted and 3D T1&rgr;-weighted magnetic resonance imaging (MRI). Further provided is a self-compensating spin-locking sequence for correcting and reducing artifacts in T1&rgr;-weighted imaging. Also provided is a sequence combining 3D T1&rgr;-weighted MRI with a self-compensating spin-locking pulse for facilitating T1&rgr;-weighted imaging with surface coils.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: December 28, 2004
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Ravinder Reddy, Sridhar R. Charagundla, Ari Borthakur, Erik M. Shapiro
  • Pulse imaging sequences and methods for T1p-weighted MRI
    Publication number: 20030218459
    Abstract: Provided are pulse imaging sequences and methods for 2D multi-slice T1&rgr;-weighted and 3D T1&rgr;-weighted magnetic resonance imaging (MRI). Further provided is a self-compensating spin-locking sequence for correcting and reducing artifacts in T1&rgr;-weighted imaging. Also provided is a sequence combining 3D T1&rgr;-weighted MRI with a self-compensating spin-locking pulse for facilitating T1&rgr;-weighted imaging with surface coils.
    Type: Application
    Filed: March 14, 2003
    Publication date: November 27, 2003
    Inventors: Ravinder Reddy, Sridhar R. Charagundla, Ari Borthakur, Erik M. Shapiro